|
1
|
Franklin Resources
San Mateo,
California
|
$143M
|
+$32.6M
|
+1,653,008
|
+28%
|
|
|
2
|
Fidelity Investments
Boston,
Massachusetts
|
$103M
|
+$773K
|
+39,154
|
+0.7%
|
|
|
3
|
Tang Capital Management
San Diego,
California
|
$98.6M
|
–
|
–
|
–
|
|
|
4
|
Janus Henderson Investors US
Denver,
Colorado
|
$66.4M
|
+$7.23M
|
+366,408
|
+12%
|
|
|
5
|
|
$59.7M
|
-$3.28M
|
-166,177
|
-5%
|
|
|
6
|
PFM Health Sciences
San Francisco,
California
|
$58.4M
|
+$5.84M
|
+296,006
|
+11%
|
|
|
7
|
Baker Bros. Advisors
New York
|
$55.2M
|
–
|
–
|
–
|
|
|
8
|
Cormorant Asset Management
Boston,
Massachusetts
|
$33.2M
|
+$1.27M
|
+64,281
|
+4%
|
|
|
9
|
Broadfin Capital
New York
|
$27.8M
|
-$15.1M
|
-766,526
|
-34%
|
|
|
10
|
State Street
Boston,
Massachusetts
|
$22.9M
|
-$4.26M
|
-215,739
|
-15%
|
|
|
11
|
Vanguard Group
Malvern,
Pennsylvania
|
$22M
|
+$1.08M
|
+54,940
|
+5%
|
|
|
12
|
|
$20.8M
|
–
|
–
|
–
|
|
|
13
|
BlackRock Fund Advisors
San Francisco,
California
|
$14.4M
|
-$712K
|
-36,101
|
-5%
|
|
|
14
|
BlackRock Institutional Trust
San Francisco,
California
|
$13.6M
|
+$197K
|
+9,979
|
+1%
|
|
|
15
|
Allianz Asset Management
Munich,
Germany
|
$8.98M
|
+$509K
|
+25,787
|
+6%
|
|
|
16
|
Kingdon Capital Management
New York
|
$8.22M
|
-$8.6M
|
-435,945
|
-50%
|
|
|
17
|
VHCP Management II
New York
|
$7.71M
|
+$8.01M
|
+405,901
|
New
|
|
|
18
|
|
$6.62M
|
+$389K
|
+19,737
|
+6%
|
|
|
19
|
Northern Trust
Chicago,
Illinois
|
$6.49M
|
-$16.4K
|
-832
|
-0.2%
|
|
|
20
|
Brown Advisory
Baltimore,
Maryland
|
$5.63M
|
-$90.5K
|
-4,585
|
-2%
|
|
|
21
|
Asset Management One
Tokyo,
Japan
|
$5.4M
|
+$568K
|
+28,799
|
+12%
|
|
|
22
|
Panagora Asset Management
Boston,
Massachusetts
|
$4.66M
|
+$2.3M
|
+116,461
|
+90%
|
|
|
23
|
Tekla Capital Management
Boston,
Massachusetts
|
$4.16M
|
–
|
–
|
–
|
|
|
24
|
Fred Alger Management
New York
|
$3.25M
|
-$1.45M
|
-73,407
|
-30%
|
|
|
25
|
Susquehanna International Group
Bala Cynwyd,
Pennsylvania
|
$3.23M
|
-$628K
|
-31,838
|
-16%
|
|
