|
1
|
Franklin Resources
San Mateo,
California
|
$133M
|
-$308K
|
-16,612
|
-0.2%
|
|
|
2
|
Tang Capital Management
San Diego,
California
|
$107M
|
–
|
–
|
–
|
|
|
3
|
Fidelity Investments
Boston,
Massachusetts
|
$101M
|
+$6.66M
|
+358,874
|
+7%
|
|
|
4
|
Janus Henderson Investors US
Denver,
Colorado
|
$69.5M
|
+$369K
|
+19,879
|
+0.5%
|
|
|
5
|
PFM Health Sciences
San Francisco,
California
|
$58.4M
|
+$726K
|
+39,148
|
+1%
|
|
|
6
|
Baker Bros. Advisors
New York
|
$49.2M
|
–
|
–
|
–
|
|
|
7
|
Broadfin Capital
New York
|
$49.1M
|
+$29.7M
|
+1,599,896
|
+128%
|
|
|
8
|
|
$47.8M
|
-$2.52M
|
-135,935
|
-5%
|
|
|
9
|
Kingdon Capital Management
New York
|
$46.5M
|
+$33.1M
|
+1,784,890
|
+196%
|
|
|
10
|
Cormorant Asset Management
Boston,
Massachusetts
|
$30.5M
|
–
|
–
|
–
|
|
|
11
|
Vanguard Group
Malvern,
Pennsylvania
|
$22.6M
|
+$1.77M
|
+95,637
|
+8%
|
|
|
12
|
State Street
Boston,
Massachusetts
|
$18.9M
|
+$1.92M
|
+103,311
|
+10%
|
|
|
13
|
|
$18.9M
|
–
|
–
|
–
|
|
|
14
|
BlackRock Fund Advisors
San Francisco,
California
|
$15.1M
|
+$944K
|
+50,875
|
+6%
|
|
|
15
|
BlackRock Institutional Trust
San Francisco,
California
|
$14.3M
|
+$1.47M
|
+79,227
|
+11%
|
|
|
16
|
Highland Capital Management (Texas)
Dallas,
Texas
|
$11.2M
|
+$12.1M
|
+650,731
|
New
|
|
|
17
|
Royal Bank of Canada
Toronto,
Ontario, Canada
|
$7.2M
|
+$7.75M
|
+417,900
|
New
|
|
|
18
|
VHCP Management II
New York
|
$6.99M
|
–
|
–
|
–
|
|
|
19
|
|
$6.66M
|
+$7.18M
|
+386,787
|
New
|
|
|
20
|
Northern Trust
Chicago,
Illinois
|
$6.17M
|
+$23.9K
|
+1,286
|
+0.4%
|
|
|
21
|
Asset Management One
Tokyo,
Japan
|
$4.69M
|
-$482K
|
-25,969
|
-9%
|
|
|
22
|
Geode Capital Management
Boston,
Massachusetts
|
$4.39M
|
+$669K
|
+36,050
|
+16%
|
|
|
23
|
Panagora Asset Management
Boston,
Massachusetts
|
$3.48M
|
-$1.11M
|
-59,641
|
-23%
|
|
|
24
|
Boxer Capital
San Diego,
California
|
$3.45M
|
+$3.71M
|
+200,000
|
New
|
|
|
25
|
Alyeska Investment Group
Chicago,
Illinois
|
$3.38M
|
+$3.64M
|
+196,342
|
New
|
|
