GPCR icon

Structure Therapeutics
GPCR

Overview Fund Activity

172 hedge funds and large institutions have $1.13B invested in Structure Therapeutics in 2025 Q2 according to their latest regulatory filings, with 38 funds opening new positions, 62 increasing their positions, 44 reducing their positions, and 17 closing their positions.

Holders
172
Holders Change
+21
Holders Change %
+13.91%
% of All Funds
2.31%
Holding in Top 10
3
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+200%
% of All Funds
0.04%
New
38
Increased
62
Reduced
44
Closed
17
Calls
$12.5M
Puts
$10.5M
Net Calls
+$1.95M
Net Calls Change
+$1.2M

Top Buyers

1
BBA
1
Baker Bros. Advisors
New York
$52M
2
DTC
2
Deep Track Capital
Connecticut
$106M
3
O
3
OrbiMed
New York
$24.9M
4
CC
4
Casdin Capital
New York
$25.4M
5
PHAM
5
Pacific Heights Asset Management
California
$9.54M

Top Sellers

1
Capital Research Global Investors
1
Capital Research Global Investors
California
$0
2
Fidelity Investments
2
Fidelity Investments
Massachusetts
$102M
3
Fidelity International
3
Fidelity International
Bermuda
$0
4
Wellington Management Group
4
Wellington Management Group
Massachusetts
$143M
5
Federated Hermes
5
Federated Hermes
Pennsylvania
$9.71M
Name Holding Trade Value Shares
Change 		Shares
Change %
SC
151
SouthState Corp
Florida
$10.4K +$10.4K +500 New
GI
152
GAMMA Investing
California
$9.98K -$539 -26 -5%
RhumbLine Advisers
153
RhumbLine Advisers
Massachusetts
$9.33K – – –
Carson Wealth (CWM LLC)
154
Carson Wealth (CWM LLC)
Nebraska
$7K +$5.03K +255 +255%
NSIM
155
North Star Investment Management
Illinois
$6.84K – – –
WWM
156
Wolff Wiese Magana
California
$5.93K +$3.15K +152 +113%
Daiwa Securities Group
157
Daiwa Securities Group
Japan
$5K – – –
National Bank of Canada
158
National Bank of Canada
Quebec, Canada
$4.15K -$57.2K -2,757 -93%
PWMG
159
Private Wealth Management Group
New Jersey
$4.07K – – –
EWA
160
EverSource Wealth Advisors
Alabama
$3.53K +$3.53K +170 New
AAS
161
Ameritas Advisory Services
Nebraska
$2.07K +$2.07K +100 New
Northwestern Mutual Wealth Management
162
Northwestern Mutual Wealth Management
Wisconsin
$1.2K +$1.2K +58 New
WTA
163
Washington Trust Advisors
Massachusetts
$850 – – –
CIBC Private Wealth Group
164
CIBC Private Wealth Group
Georgia
$684 +$684 +33 New
BIG
165
Brooklyn Investment Group
New York
$664 +$664 +32 New
FDCDDQ
166
Federation des caisses Desjardins du Quebec
Quebec, Canada
$415 – – –
US Bancorp
167
US Bancorp
Minnesota
$270 – – –
MCM
168
MAI Capital Management
Ohio
$208 – – –
GRP
169
Global Retirement Partners
California
$207 +$207 +10 New
CFB
170
Cullen/Frost Bankers
Texas
$166 – – –
HNB
171
Huntington National Bank
Ohio
$41 – – –
PAS
172
Point72 Asia (Singapore)
Singapore
$21 – – –
Capital Research Global Investors
173
Capital Research Global Investors
California
– -$37.5M -2,164,145 Closed
Fidelity International
174
Fidelity International
Bermuda
– -$19.9M -1,150,440 Closed
CCM
175
Camber Capital Management
Massachusetts
– -$5.19M -300,000 Closed
4 5 6
7
8