GPCR icon

Structure Therapeutics

196 hedge funds and large institutions have $4.64B invested in Structure Therapeutics in 2025 Q4 according to their latest regulatory filings, with 70 funds opening new positions, 52 increasing their positions, 62 reducing their positions, and 27 closing their positions.

New
Increased
Maintained
Reduced
Closed

more funds holding in top 10

Funds holding in top 10:

more call options, than puts

Call options by funds: $ | Put options by funds: $

more capital invested

Capital invested by funds: $ → $

more first-time investments, than exits

New positions opened: | Existing positions closed:

26% more funds holding

Funds holding: 156196 (+40)

11.44% more ownership

Funds ownership: 98.33%109.77% (+11%)

16% less repeat investments, than reductions

Existing positions increased: 52 | Existing positions reduced: 62

Holders
196
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
16
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$62.6M
Puts
$18.2M
Net Calls
Net Calls Change

Top Sellers

1 -$45.8M
2 -$42.5M
3 -$38.3M
4
Invesco
Invesco
Georgia
-$18M
5
CCM
Catalio Capital Management
New York
-$16.3M
Name Holding Trade Value Shares
Change
Change in
Stake
VPC
101
Vestal Point Capital
New York
$2.43M
TI
102
TrueMark Investments
Illinois
$2.36M
Bank of America
103
Bank of America
North Carolina
$2.2M
DA
104
DCF Advisers
Connecticut
$2.09M
Nomura Asset Management
105
Nomura Asset Management
Japan
$2.03M
Russell Investments Group
106
Russell Investments Group
United Kingdom
$1.83M
ETC
107
Exchange Traded Concepts
Oklahoma
$1.81M
QOP
108
Quinn Opportunity Partners
Virginia
$1.74M
SAM
109
Sectoral Asset Management
Quebec, Canada
$1.66M
MS
110
Maven Securities
Jersey
$1.39M
XT
111
XTX Topco
Cayman Islands
$1.33M
Acadian Asset Management
112
Acadian Asset Management
Massachusetts
$1.22M
TRSOTSOK
113
Teachers Retirement System of the State of Kentucky
Kentucky
$1.2M
SEI Investments
114
SEI Investments
Pennsylvania
$1.04M
WC
115
Wexford Capital
Florida
$1.03M
JGC
116
J. Goldman & Co
New York
$946K
BM
117
Brandywine Managers
Delaware
$929K
JP Morgan Chase
118
JP Morgan Chase
New York
$901K
QC
119
Quadrature Capital
United Kingdom
$888K
DnB Asset Management
120
DnB Asset Management
Norway
$879K
Allianz Asset Management
121
Allianz Asset Management
Germany
$835K
Envestnet Asset Management
122
Envestnet Asset Management
Illinois
$805K
CUAMC
123
China Universal Asset Management Company
China
$757K
Royal Bank of Canada
124
Royal Bank of Canada
Ontario, Canada
$709K
SG Americas Securities
125
SG Americas Securities
New York
$706K