XT
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XTX Topco’s Structure Therapeutics GPCR Stock Holding History

XTX Topco’s Portfolio GPCR Stock Details GPCR Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$1.49M Buy
30,921
+11,728
+61% +$803K 0.03% 1089
2025
Q4 		$1.33M Buy
+19,193
New +$784K 0.04% 824
2024
Q4 		– Sell
-11,938
Closed -$524K – 2525
2024
Q3 		$524K Buy
11,938
+5,997
+101% +$232K 0.04% 783
2024
Q2 		$233K Sell
5,941
-1,034
-15% -$42.5K 0.02% 1127
2024
Q1 		$299K Buy
+6,975
New +$294K 0.04% 862

Other funds holding GPCR

Fidelity Investments
Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return
Wellington Management Group
Wellington Management Group Boston, Massachusetts $535B AUM 26.23% 1-Year Est. Return
ACA
Avoro Capital Advisors New York $10.2B AUM 149.19% 1-Year Est. Return
Janus Henderson Group
Janus Henderson Group London, United Kingdom $209B AUM 37.72% 1-Year Est. Return
DTC
Deep Track Capital Greenwich, Connecticut $6.12B AUM 144% 1-Year Est. Return
BI
BVF Inc San Francisco, California $3.14B AUM 249.53% 1-Year Est. Return
Morgan Stanley
Morgan Stanley New York $1.66T AUM 25.57% 1-Year Est. Return
T. Rowe Price Associates
T. Rowe Price Associates Baltimore, Maryland $865B AUM 30.76% 1-Year Est. Return
Principal Financial Group
Principal Financial Group Des Moines, Iowa $187B AUM 18.48% 1-Year Est. Return
DCM
Driehaus Capital Management Chicago, Illinois $13.6B AUM 173.98% 1-Year Est. Return

XTX Topco's GPCR Position: Q1 2026 in Review

XTX Topco increased its Structure Therapeutics (GPCR) stake by 61% in Q1 2026, buying an estimated $803K and bringing the position to 30,921 shares worth $1.49M. The position accounts for 0.03% of the portfolio, ranked #1089.

XTX Topco first reported a position in GPCR in Q1 2024 and has held it in 5 quarters since. 196 funds tracked by Wall St. Rank hold GPCR as of Q1 2026.

  • XTX Topco held 30,921 shares of Structure Therapeutics worth $1.49M as of Q1 2026.
  • XTX Topco bought 11,728 Structure Therapeutics shares in Q1 2026, an estimated $803K.
  • Structure Therapeutics made up 0.03% of XTX Topco's portfolio in Q1 2026, its #1089 holding.
  • XTX Topco first reported a position in Structure Therapeutics in Q1 2024 and has held it in 5 quarters since.
  • 196 funds tracked by Wall St. Rank held Structure Therapeutics as of Q1 2026.

Based on XTX Topco's 13F filing for Q1 2026, filed 15 May 2026.