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Fulcrum Therapeutics

122 hedge funds and large institutions have $374M invested in Fulcrum Therapeutics in 2025 Q2 according to their latest regulatory filings, with 24 funds opening new positions, 34 increasing their positions, 46 reducing their positions, and 19 closing their positions.

New
Increased
Maintained
Reduced
Closed

874% more call options, than puts

Call options by funds: $6.27M | Put options by funds: $643K

152% more capital invested

Capital invested by funds: $148M → $374M (+$226M)

26% more first-time investments, than exits

New positions opened: 24 | Existing positions closed: 19

5.62% more ownership

Funds ownership: 95.16%100.78% (+5.6%)

4% more funds holding

Funds holding: 117122 (+5)

26% less repeat investments, than reductions

Existing positions increased: 34 | Existing positions reduced: 46

Holders
122
Holders Change
+5
Holders Change %
+4.27%
% of All Funds
1.61%
Holding in Top 10
2
Holding in Top 10 Change
+2
Holding in Top 10 Change %
% of All Funds
0.03%
New
24
Increased
34
Reduced
46
Closed
19
Calls
$6.27M
Puts
$643K
Net Calls
+$5.62M
Net Calls Change
+$5.51M
Name Holding Trade Value Shares
Change
Change in
Stake
MC
76
Matisse Capital
Oregon
$180K -$378K -70,617 -73%
Citigroup
77
Citigroup
New York
$145K -$89.9K -16,813 -44%
Manulife (Manufacturers Life Insurance)
78
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$137K -$13.5K -2,524 -11%
AQR Capital Management
79
AQR Capital Management
Connecticut
$124K +$2.38K +445 +3%
Legal & General Group
80
Legal & General Group
United Kingdom
$120K +$65.1K +12,173 +230%
Jane Street
81
Jane Street
New York
$120K -$537K -100,389 -85%
Creative Planning
82
Creative Planning
Kansas
$117K +$90.6K +16,939 New
ECM
83
Evergreen Capital Management
Washington
$114K +$88.3K +16,502 New
VOYA Investment Management
84
VOYA Investment Management
Georgia
$106K -$16.8K -3,137 -17%
Prudential Financial
85
Prudential Financial
New Jersey
$100K -$43.8K -8,185 -36%
AI
86
Alphabet Inc
California
$98.1K
Squarepoint
87
Squarepoint
New York
$94.1K +$73.1K +13,675 New
Los Angeles Capital Management
88
Los Angeles Capital Management
California
$92.6K +$72K +13,465 New
New York State Common Retirement Fund
89
New York State Common Retirement Fund
New York
$90.1K
VPIM
90
Vanguard Personalized Indexing Management
California
$89K +$14.3K +2,677 +26%
PFSRSONJ
91
Police & Firemen's Retirement System of New Jersey
New Jersey
$85.8K
GCM
92
Graham Capital Management
Connecticut
$82.9K -$825K -154,191 -93%
ProShare Advisors
93
ProShare Advisors
Maryland
$75.3K -$3.78K -706 -6%
Russell Investments Group
94
Russell Investments Group
United Kingdom
$64K +$48.6K +9,092 +4,209%
Fidelity Investments
95
Fidelity Investments
Massachusetts
$47.9K +$14.2K +2,649 +61%
TRCT
96
Tower Research Capital (TRC)
New York
$43.9K -$10.5K -1,955 -23%
BIG
97
Brooklyn Investment Group
New York
$43.2K -$31.6K -5,909 -48%
AIP
98
Ameritas Investment Partners
Nebraska
$41.8K
BNP Paribas Financial Markets
99
BNP Paribas Financial Markets
France
$41.3K -$51.3K -9,587 -62%
Group One Trading
100
Group One Trading
Illinois
$38.7K -$6.27K -1,173 -17%

FULC Hedge Fund Activity: Q2 2025 in Review

122 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Fulcrum Therapeutics (FULC) for Q2 2025, worth a combined $374M — up 152% from $148M a quarter earlier.

Buyers outnumbered sellers: 24 funds opened new FULC positions and 19 closed out — a net gain of 5 holders — while 34 added to existing stakes and 46 trimmed.

The largest buyer was Adage Capital Partners, adding an estimated $8.5M. The largest seller was Nantahala Capital Management, cutting an estimated $2.86M.

  • 122 institutional investors held Fulcrum Therapeutics (FULC) as of Q2 2025, up from 117 in Q1 2025.
  • Funds reported $374M of Fulcrum Therapeutics stock for Q2 2025, up 152% quarter-over-quarter.
  • 24 funds opened new Fulcrum Therapeutics positions in Q2 2025 and 19 closed out, a net change of +5 holders.
  • The largest Fulcrum Therapeutics buyer in Q2 2025 was Adage Capital Partners, an estimated $8.5M added.
  • The largest Fulcrum Therapeutics seller in Q2 2025 was Nantahala Capital Management, an estimated $2.86M sold.

Based on aggregated 13F filings for Q2 2025.