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Fulcrum Therapeutics
FULC

Overview Fund Activity

120 hedge funds and large institutions have $374M invested in Fulcrum Therapeutics in 2025 Q2 according to their latest regulatory filings, with 23 funds opening new positions, 33 increasing their positions, 46 reducing their positions, and 19 closing their positions.

Holders
120
Holders Change
+3
Holders Change %
+2.56%
% of All Funds
1.61%
Holding in Top 10
2
Holding in Top 10 Change
+2
Holding in Top 10 Change %
%
% of All Funds
0.03%
New
23
Increased
33
Reduced
46
Closed
19
Calls
$5.41M
Puts
$466K
Net Calls
+$4.94M
Net Calls Change
+$4.83M

Top Buyers

1
Adage Capital Partners
1
Adage Capital Partners
Massachusetts
$31.6M
2
Balyasny Asset Management
2
Balyasny Asset Management
Illinois
$9.21M
3
Goldman Sachs
3
Goldman Sachs
New York
$7.87M
4
D.E. Shaw & Co
4
D.E. Shaw & Co
New York
$8.1M
5
Point72 Asset Management
5
Point72 Asset Management
Connecticut
$3.43M

Top Sellers

1
NCM
1
Nantahala Capital Management
Connecticut
$29.5M
2
ACM
2
ADAR1 Capital Management
Texas
$367K
3
BlackRock
3
BlackRock
New York
$30.1M
4
Renaissance Technologies
4
Renaissance Technologies
New York
$540K
5
EAM
5
Exome Asset Management
New York
$3.06M
Name Market Value Shares Shares
Change 		Shares
Change %
RCM
1
RA Capital Management
Massachusetts
$70.4M 10,229,099 – –
TCM
2
TCG Crossover Management
California
$36.1M 5,250,000 – –
SCM
3
Suvretta Capital Management
New York
$35M 5,082,900 +15,506 +0.3%
Adage Capital Partners
4
Adage Capital Partners
Massachusetts
$31.6M 4,589,000 +1,589,000 +53%
BlackRock
5
BlackRock
New York
$30.1M 4,379,023 -331,674 -7%
NCM
6
Nantahala Capital Management
Connecticut
$29.5M 4,288,299 -534,394 -11%
Vanguard Group
7
Vanguard Group
Pennsylvania
$21.6M 3,146,443 -73,935 -2%
Dimensional Fund Advisors
8
Dimensional Fund Advisors
Texas
$9.44M 1,372,637 -34,412 -2%
Balyasny Asset Management
9
Balyasny Asset Management
Illinois
$9.21M 1,338,214 +1,338,214 New
State Street
10
State Street
Massachusetts
$8.38M 1,218,366 -34,074 -3%
Geode Capital Management
11
Geode Capital Management
Massachusetts
$8.21M 1,193,138 -38,237 -3%
D.E. Shaw & Co
12
D.E. Shaw & Co
New York
$8.1M 1,176,711 +596,050 +103%
Goldman Sachs
13
Goldman Sachs
New York
$7.87M 1,143,536 +740,936 +184%
WP
14
Woodline Partners
California
$6.18M 897,617 – –
Northern Trust
15
Northern Trust
Illinois
$4.21M 611,536 -29,411 -5%
Acadian Asset Management
16
Acadian Asset Management
Massachusetts
$3.87M 563,380 +218,819 +64%
Point72 Asset Management
17
Point72 Asset Management
Connecticut
$3.43M 498,219 +498,219 New
Invesco
18
Invesco
Georgia
$3.24M 470,333 +384,566 +448%
EAM
19
Exome Asset Management
New York
$3.06M 444,949 -244,188 -35%
IC
20
Ikarian Capital
Texas
$2.95M 428,521 +228,425 +114%
Charles Schwab
21
Charles Schwab
California
$2.67M 387,782 +6,423 +2%
Connor, Clark & Lunn Investment Management (CC&L)
22
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$2.36M 342,547 +124,798 +57%
Morgan Stanley
23
Morgan Stanley
New York
$2.16M 314,410 +28,811 +10%
Bessemer Group
24
Bessemer Group
New Jersey
$1.98M 286,988 – –
Deutsche Bank
25
Deutsche Bank
Germany
$1.92M 279,251 -561 -0.2%
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