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Fulcrum Therapeutics

117 hedge funds and large institutions have $148M invested in Fulcrum Therapeutics in 2025 Q1 according to their latest regulatory filings, with 17 funds opening new positions, 31 increasing their positions, 44 reducing their positions, and 19 closing their positions.

New
Increased
Maintained
Reduced
Closed

270% more call options, than puts

Call options by funds: $148K | Put options by funds: $40K

0.74% less ownership

Funds ownership: 95.9%95.16% (-0.74%)

2% less funds holding

Funds holding: 119117 (-2)

11% less first-time investments, than exits

New positions opened: 17 | Existing positions closed: 19

30% less repeat investments, than reductions

Existing positions increased: 31 | Existing positions reduced: 44

39% less capital invested

Capital invested by funds: $243M → $148M (-$95M)

Holders
117
Holders Change
-2
Holders Change %
-1.68%
% of All Funds
1.57%
Holding in Top 10
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
17
Increased
31
Reduced
44
Closed
19
Calls
$148K
Puts
$40K
Net Calls
+$108K
Net Calls Change
-$5.12M
Name Holding Trade Value Shares
Change
Change in
Stake
RCM
1
RA Capital Management
Massachusetts
$29.5M
TCM
2
TCG Crossover Management
California
$15.1M
SCM
3
Suvretta Capital Management
New York
$14.6M +$6.35M +1,728,928 +52%
NCM
4
Nantahala Capital Management
Connecticut
$13.9M +$158K +42,985 +0.9%
BlackRock
5
BlackRock
New York
$13.6M -$1.69M -458,732 -9%
Vanguard Group
6
Vanguard Group
Pennsylvania
$9.27M -$107K -29,229 -0.9%
Adage Capital Partners
7
Adage Capital Partners
Massachusetts
$8.64M
Dimensional Fund Advisors
8
Dimensional Fund Advisors
Texas
$4.05M -$42.8K -11,641 -0.8%
State Street
9
State Street
Massachusetts
$3.61M +$26.2K +7,121 +0.6%
Geode Capital Management
10
Geode Capital Management
Massachusetts
$3.55M -$232K -63,140 -5%
WP
11
Woodline Partners
California
$2.59M -$1.88M -512,903 -36%
EAM
12
Exome Asset Management
New York
$1.98M +$1.49M +405,538 +143%
Northern Trust
13
Northern Trust
Illinois
$1.85M -$255K -69,374 -10%
D.E. Shaw & Co
14
D.E. Shaw & Co
New York
$1.67M -$9.34K -2,542 -0.4%
ACM
15
ADAR1 Capital Management
Texas
$1.41M +$1.08M +294,284 +150%
Goldman Sachs
16
Goldman Sachs
New York
$1.16M -$513K -139,658 -26%
Renaissance Technologies
17
Renaissance Technologies
New York
$1.16M +$1.47M +401,100 New
Charles Schwab
18
Charles Schwab
California
$1.1M -$531K -144,686 -28%
Citadel Advisors
19
Citadel Advisors
Florida
$1.08M +$150K +40,933 +12%
Acadian Asset Management
20
Acadian Asset Management
Massachusetts
$989K +$1.13M +308,854 +865%
Bessemer Group
21
Bessemer Group
New Jersey
$827K
Morgan Stanley
22
Morgan Stanley
New York
$823K -$4.58M -1,246,133 -81%
Deutsche Bank
23
Deutsche Bank
Germany
$806K -$20.9K -5,679 -2%
Two Sigma Advisers
24
Two Sigma Advisers
New York
$800K -$242K -65,800 -19%
SC
25
Shay Capital
New York
$646K -$283K -77,159 -26%

FULC Hedge Fund Activity: Q1 2025 in Review

117 of the 7,459 institutional investors tracked by Wall St. Rank reported a position in Fulcrum Therapeutics (FULC) for Q1 2025, worth a combined $148M — down 39% from $243M a quarter earlier.

Sellers outnumbered buyers: 19 funds closed out of FULC and 17 opened new positions — a net loss of 2 holders — while 44 trimmed existing stakes and 31 added.

The largest buyer was Suvretta Capital Management, adding an estimated $6.35M. The largest seller was Morgan Stanley, cutting an estimated $4.58M.

  • 117 institutional investors held Fulcrum Therapeutics (FULC) as of Q1 2025, down from 119 in Q4 2024.
  • Funds reported $148M of Fulcrum Therapeutics stock for Q1 2025, down 39% quarter-over-quarter.
  • 17 funds opened new Fulcrum Therapeutics positions in Q1 2025 and 19 closed out, a net change of -2 holders.
  • The largest Fulcrum Therapeutics buyer in Q1 2025 was Suvretta Capital Management, an estimated $6.35M added.
  • The largest Fulcrum Therapeutics seller in Q1 2025 was Morgan Stanley, an estimated $4.58M sold.

Based on aggregated 13F filings for Q1 2025.