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Fulcrum Therapeutics
FULC

Overview Fund Activity

117 hedge funds and large institutions have $148M invested in Fulcrum Therapeutics in 2025 Q1 according to their latest regulatory filings, with 18 funds opening new positions, 31 increasing their positions, 43 reducing their positions, and 19 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
117
Holders Change
-2
Holders Change %
-1.68%
% of All Funds
1.59%
Holding in Top 10
–
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
–
New
18
Increased
31
Reduced
43
Closed
19
Calls
$148K
Puts
$40K
Net Calls
+$108K
Net Calls Change
-$5.12M

Top Buyers

1
SCM
Suvretta Capital Management
New York
+$4.98M
2
EAM
Exome Asset Management
New York
+$1.17M
3
Renaissance Technologies
Renaissance Technologies
New York
+$1.16M
4
Acadian Asset Management
Acadian Asset Management
Massachusetts
+$887K
5
ACM
ADAR1 Capital Management
Texas
+$848K

Top Sellers

1
Morgan Stanley
Morgan Stanley
New York
-$3.59M
2
WP
Woodline Partners
California
-$1.48M
3
BlackRock
BlackRock
New York
-$1.32M
4
PA
Perceptive Advisors
New York
-$1.12M
5
Wellington Management Group
Wellington Management Group
Massachusetts
-$809K
Name Holding Trade Value Shares
Change 		Shares
Change %
RCM
1
RA Capital Management
Massachusetts
$29.5M – – –
TCM
2
TCG Crossover Management
California
$15.1M – – –
SCM
3
Suvretta Capital Management
New York
$14.6M +$4.98M +1,728,928 +52%
NCM
4
Nantahala Capital Management
Connecticut
$13.9M +$124K +42,985 +0.9%
BlackRock
5
BlackRock
New York
$13.6M -$1.32M -458,732 -9%
Vanguard Group
6
Vanguard Group
Pennsylvania
$9.27M -$84.2K -29,229 -0.9%
Adage Capital Partners
7
Adage Capital Partners
Massachusetts
$8.64M – – –
Dimensional Fund Advisors
8
Dimensional Fund Advisors
Texas
$4.05M -$33.5K -11,641 -0.8%
State Street
9
State Street
Massachusetts
$3.61M +$20.5K +7,121 +0.6%
Geode Capital Management
10
Geode Capital Management
Massachusetts
$3.55M -$182K -63,140 -5%
WP
11
Woodline Partners
California
$2.59M -$1.48M -512,903 -36%
EAM
12
Exome Asset Management
New York
$1.98M +$1.17M +405,538 +143%
Northern Trust
13
Northern Trust
Illinois
$1.85M -$200K -69,374 -10%
D.E. Shaw & Co
14
D.E. Shaw & Co
New York
$1.67M -$7.32K -2,542 -0.4%
ACM
15
ADAR1 Capital Management
Texas
$1.41M +$848K +294,284 +150%
Goldman Sachs
16
Goldman Sachs
New York
$1.16M -$402K -139,658 -26%
Renaissance Technologies
17
Renaissance Technologies
New York
$1.16M +$1.16M +401,100 New
Charles Schwab
18
Charles Schwab
California
$1.1M -$417K -144,686 -28%
Citadel Advisors
19
Citadel Advisors
Florida
$1.08M +$118K +40,933 +12%
Acadian Asset Management
20
Acadian Asset Management
Massachusetts
$989K +$887K +308,854 +865%
Bessemer Group
21
Bessemer Group
New Jersey
$827K – – –
Morgan Stanley
22
Morgan Stanley
New York
$823K -$3.59M -1,246,133 -81%
Deutsche Bank
23
Deutsche Bank
Germany
$806K -$16.4K -5,679 -2%
Two Sigma Advisers
24
Two Sigma Advisers
New York
$800K -$190K -65,800 -19%
SC
25
Shay Capital
New York
$646K -$222K -77,159 -26%
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