Jane Street
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Jane Street’s Fulcrum Therapeutics FULC Stock Holding History

Jane Street’s Portfolio FULC Stock Details FULC Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q3 		$1.93M Sell
522,521
-1,694,977
-76% -$6.36M ﹤0.01% 5224
2026
Q2 		$8.12M Buy
2,217,498
+1,907,081
+614% +$11.6M ﹤0.01% 3090
2026
Q1 		$2.38M Sell
310,417
-183,333
-37% -$1.7M ﹤0.01% 4750
2025
Q4 		$5.58M Buy
493,750
+172,230
+54% +$1.75M ﹤0.01% 3065
2025
Q3 		$2.96M Buy
321,520
+304,093
+1,745% +$2.2M ﹤0.01% 4247
2025
Q2 		$120K Sell
17,427
-100,389
-85% -$537K ﹤0.01% 8873
2025
Q1 		$339K Buy
117,816
+72,657
+161% +$267K ﹤0.01% 7592
2024
Q4 		$212K Sell
45,159
-74,734
-62% -$276K ﹤0.01% 8314
2024
Q3 		$428K Sell
119,893
-48,351
-29% -$359K ﹤0.01% 7468
2024
Q2 		$1.04M Sell
168,244
-366,818
-69% -$2.78M ﹤0.01% 5680
2024
Q1 		$5.05M Buy
535,062
+188,212
+54% +$1.68M ﹤0.01% 2591
2023
Q4 		$2.34M Buy
346,850
+308,349
+801% +$1.37M ﹤0.01% 4053
2023
Q3 		$171K Sell
38,501
-27,792
-42% -$121K ﹤0.01% 7722
2023
Q2 		$219K Buy
66,293
+52,039
+365% +$153K ﹤0.01% 7572
2023
Q1 		$40.6K Buy
14,254
+2,567
+22% +$23K ﹤0.01% 8506
2022
Q4 		$85.1K Buy
+11,687
New +$76.2K ﹤0.01% 8186
2022
Q3 		– Sell
-37,930
Closed -$186K – 9939
2022
Q2 		$186K Buy
37,930
+22,972
+154% +$224K ﹤0.01% 8249
2022
Q1 		$354K Sell
14,958
-16,281
-52% -$230K ﹤0.01% 8112
2021
Q4 		$552K Sell
31,239
-18,703
-37% -$370K ﹤0.01% 7070
2021
Q3 		$1.41M Buy
+49,942
New +$946K ﹤0.01% 5222

Other funds holding FULC

BlackRock
BlackRock New York $6.79T AUM 37.06% 1-Year Est. Return
Nantahala Capital Management
Nantahala Capital Management New Canaan, Connecticut $3.16B AUM 31.44% 1-Year Est. Return
Vanguard Capital Management
Vanguard Capital Management Malvern, Pennsylvania $4.76T AUM
Renaissance Technologies
Renaissance Technologies New York $73.4B AUM 32.8% 1-Year Est. Return
Marshall Wace
Marshall Wace London, United Kingdom $114B AUM 35.47% 1-Year Est. Return
GSK plc
GSK plc London $497M AUM 35.1% 1-Year Est. Return
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.92T AUM 36.1% 1-Year Est. Return
Qube Research & Technologies (QRT)
Qube Research & Technologies (QRT) London, United Kingdom $123B AUM 30.05% 1-Year Est. Return
State Street
State Street Boston, Massachusetts $3.44T AUM 36.12% 1-Year Est. Return
Vanguard Portfolio Management
Vanguard Portfolio Management Malvern, Pennsylvania $2.21T AUM

Jane Street's FULC Position: Q3 2026 in Review

Jane Street reduced its Fulcrum Therapeutics (FULC) stake by 76% in Q3 2026, selling an estimated $6.36M and leaving 522,521 shares worth $1.93M. The position accounts for ﹤0.01% of the portfolio, ranked #5224.

Jane Street first reported a position in FULC in Q3 2021 and has held it in 20 quarters since. The position peaked at $8.12M in Q2 2026. 97 funds tracked by Wall St. Rank hold FULC as of Q3 2026.

  • Jane Street held 522,521 shares of Fulcrum Therapeutics worth $1.93M as of Q3 2026.
  • Jane Street sold 1,694,977 Fulcrum Therapeutics shares in Q3 2026, an estimated $6.36M.
  • Fulcrum Therapeutics made up ﹤0.01% of Jane Street's portfolio in Q3 2026, its #5224 holding.
  • Jane Street first reported a position in Fulcrum Therapeutics in Q3 2021 and has held it in 20 quarters since.
  • Jane Street's Fulcrum Therapeutics position peaked at $8.12M in Q2 2026.
  • 97 funds tracked by Wall St. Rank held Fulcrum Therapeutics as of Q3 2026.

Based on Jane Street's 13F filing for Q3 2026, filed 12 Nov 2026.