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Fulcrum Therapeutics

117 hedge funds and large institutions have $148M invested in Fulcrum Therapeutics in 2025 Q1 according to their latest regulatory filings, with 17 funds opening new positions, 31 increasing their positions, 44 reducing their positions, and 19 closing their positions.

New
Increased
Maintained
Reduced
Closed

270% more call options, than puts

Call options by funds: $148K | Put options by funds: $40K

0.74% less ownership

Funds ownership: 95.9% β†’ 95.16% (-0.74%)

2% less funds holding

Funds holding: 119 β†’ 117 (-2)

11% less first-time investments, than exits

New positions opened: 17 | Existing positions closed: 19

30% less repeat investments, than reductions

Existing positions increased: 31 | Existing positions reduced: 44

39% less capital invested

Capital invested by funds: $243M β†’ $148M (-$95M)

Holders
117
Holders Change
-2
Holders Change %
-1.68%
% of All Funds
1.57%
Holding in Top 10
–
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
–
New
17
Increased
31
Reduced
44
Closed
19
Calls
$148K
Puts
$40K
Net Calls
+$108K
Net Calls Change
-$5.12M
Name Holding Trade Value Shares
Change
Change in
Stake
Connor, Clark & Lunn Investment Management (CC&L)
26
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$627K -$550K -149,845 -41%
JP Morgan Chase
27
JP Morgan Chase
New York
$604K +$480K +130,773 +165%
CCM
28
Catalio Capital Management
New York
$582K +$742K +202,139 New
IC
29
Ikarian Capital
Texas
$576K – – –
DekaBank Deutsche Girozentrale
30
DekaBank Deutsche Girozentrale
Germany
$568K – – –
PCM
31
Prelude Capital Management
New York
$554K +$390K +106,122 +123%
GCM
32
Graham Capital Management
Connecticut
$479K +$78.2K +21,301 +15%
N
33
Nuveen
North Carolina
$441K -$60.8K -16,557 -10%
SFI
34
Susquehanna Fundamental Investments
Pennsylvania
$434K -$230K -62,570 -29%
Two Sigma Investments
35
Two Sigma Investments
New York
$433K -$70.8K -19,268 -11%
Jacobs Levy Equity Management
36
Jacobs Levy Equity Management
New Jersey
$425K +$542K +147,654 New
Bank of New York Mellon
37
Bank of New York Mellon
New York
$414K +$6.3K +1,715 +1%
FT
38
Fiduciary Trust
Massachusetts
$393K – – –
American Century Companies
39
American Century Companies
Missouri
$356K +$11.4K +3,100 +3%
Jane Street
40
Jane Street
New York
$339K +$267K +72,657 +161%
BCM
41
Bridgeway Capital Management
Texas
$281K -$156K -42,400 -30%
MC
42
Matisse Capital
Oregon
$279K -$117K -31,728 -25%
SO
43
STRS Ohio
Ohio
$263K – – –
RhumbLine Advisers
44
RhumbLine Advisers
Massachusetts
$256K +$1.42K +386 +0.4%
Invesco
45
Invesco
Georgia
$247K +$205K +55,791 +186%
Commonwealth Equity Services
46
Commonwealth Equity Services
Massachusetts
$240K – – –
Barclays
47
Barclays
United Kingdom
$237K -$146K -39,613 -32%
SAM
48
Simplify Asset Management
Nevada
$234K +$1.54K +420 +0.5%
RC
49
RBF Capital
California
$232K – – –
HSBC Holdings
50
HSBC Holdings
United Kingdom
$219K -$3.67K -998 -1%

FULC Hedge Fund Activity: Q1 2025 in Review

117 of the 7,459 institutional investors tracked by Wall St. Rank reported a position in Fulcrum Therapeutics (FULC) for Q1 2025, worth a combined $148M β€” down 39% from $243M a quarter earlier.

Sellers outnumbered buyers: 19 funds closed out of FULC and 17 opened new positions β€” a net loss of 2 holders β€” while 44 trimmed existing stakes and 31 added.

The largest buyer was Suvretta Capital Management, adding an estimated $6.35M. The largest seller was Morgan Stanley, cutting an estimated $4.58M.

  • 117 institutional investors held Fulcrum Therapeutics (FULC) as of Q1 2025, down from 119 in Q4 2024.
  • Funds reported $148M of Fulcrum Therapeutics stock for Q1 2025, down 39% quarter-over-quarter.
  • 17 funds opened new Fulcrum Therapeutics positions in Q1 2025 and 19 closed out, a net change of -2 holders.
  • The largest Fulcrum Therapeutics buyer in Q1 2025 was Suvretta Capital Management, an estimated $6.35M added.
  • The largest Fulcrum Therapeutics seller in Q1 2025 was Morgan Stanley, an estimated $4.58M sold.

Based on aggregated 13F filings for Q1 2025.