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Fulcrum Therapeutics
FULC

Overview Fund Activity

120 hedge funds and large institutions have $374M invested in Fulcrum Therapeutics in 2025 Q2 according to their latest regulatory filings, with 23 funds opening new positions, 33 increasing their positions, 46 reducing their positions, and 19 closing their positions.

Holders
120
Holders Change
+3
Holders Change %
+2.56%
% of All Funds
1.61%
Holding in Top 10
2
Holding in Top 10 Change
+2
Holding in Top 10 Change %
%
% of All Funds
0.03%
New
23
Increased
33
Reduced
46
Closed
19
Calls
$5.41M
Puts
$466K
Net Calls
+$4.94M
Net Calls Change
+$4.83M

Top Buyers

1
Adage Capital Partners
1
Adage Capital Partners
Massachusetts
$31.6M
2
Balyasny Asset Management
2
Balyasny Asset Management
Illinois
$9.21M
3
Goldman Sachs
3
Goldman Sachs
New York
$7.87M
4
D.E. Shaw & Co
4
D.E. Shaw & Co
New York
$8.1M
5
Point72 Asset Management
5
Point72 Asset Management
Connecticut
$3.43M

Top Sellers

1
NCM
1
Nantahala Capital Management
Connecticut
$29.5M
2
ACM
2
ADAR1 Capital Management
Texas
$367K
3
BlackRock
3
BlackRock
New York
$30.1M
4
Renaissance Technologies
4
Renaissance Technologies
New York
$540K
5
EAM
5
Exome Asset Management
New York
$3.06M
Name Market Value Shares Shares
Change 		Shares
Change %
SSA
26
Schonfeld Strategic Advisors
New York
$1.41M 204,400 +204,400 New
CCM
27
Catalio Capital Management
New York
$1.3M 188,304 -13,835 -7%
Citadel Advisors
28
Citadel Advisors
Florida
$1.14M 166,234 -208,022 -56%
PCM
29
Prelude Capital Management
New York
$985K 143,129 -49,078 -26%
BFM
30
Boothbay Fund Management
New York
$973K 141,378 +81,845 +137%
Bank of New York Mellon
31
Bank of New York Mellon
New York
$943K 137,000 -6,588 -5%
FT
32
Fiduciary Trust
Massachusetts
$939K 136,555 – –
UBS Group
33
UBS Group
Switzerland
$930K 135,205 +63,285 +88%
American Century Companies
34
American Century Companies
Missouri
$911K 132,349 +8,638 +7%
Wellington Management Group
35
Wellington Management Group
Massachusetts
$870K 126,402 +126,402 New
NL
36
Nuveen LLC
North Carolina
$858K 124,723 -28,269 -18%
Barclays
37
Barclays
United Kingdom
$771K 112,063 +29,606 +36%
SFI
38
Susquehanna Fundamental Investments
Pennsylvania
$768K 111,582 -39,061 -26%
Simplex Trading
39
Simplex Trading
Illinois
$752K 109,365 +106,339 +3,514%
Millennium Management
40
Millennium Management
New York
$727K 105,693 +65,001 +160%
Susquehanna International Group
41
Susquehanna International Group
Pennsylvania
$684K 99,490 +34,650 +53%
BCM
42
Bridgeway Capital Management
Texas
$671K 97,600 – –
Jacobs Levy Equity Management
43
Jacobs Levy Equity Management
New Jersey
$636K 92,470 -55,184 -37%
MAM
44
Martingale Asset Management
Massachusetts
$626K 91,015 +91,015 New
DekaBank Deutsche Girozentrale
45
DekaBank Deutsche Girozentrale
Germany
$616K 60,000 – –
Commonwealth Equity Services
46
Commonwealth Equity Services
Massachusetts
$574K 83,428 – –
RhumbLine Advisers
47
RhumbLine Advisers
Massachusetts
$573K 83,250 -5,743 -6%
Two Sigma Advisers
48
Two Sigma Advisers
New York
$565K 82,100 -195,700 -70%
RC
49
RBF Capital
California
$554K 80,506 – –
Renaissance Technologies
50
Renaissance Technologies
New York
$540K 78,500 -322,600 -80%
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