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Amicus Therapeutics
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Overview Fund Activity

268 hedge funds and large institutions have $1.83B invested in Amicus Therapeutics in 2025 Q2 according to their latest regulatory filings, with 35 funds opening new positions, 118 increasing their positions, 81 reducing their positions, and 47 closing their positions.

Holders
268
Holders Change
-13
Holders Change %
-4.63%
% of All Funds
3.6%
Holding in Top 10
4
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-20%
% of All Funds
0.05%
New
35
Increased
118
Reduced
81
Closed
47
Calls
$2.41M
Puts
$1.56M
Net Calls
+$846K
Net Calls Change
+$2.68M

Top Buyers

1
VPC
1
Vestal Point Capital
New York
$68.2M
2
D.E. Shaw & Co
2
D.E. Shaw & Co
New York
$36.5M
3
Millennium Management
3
Millennium Management
New York
$42.5M
4
Assenagon Asset Management
4
Assenagon Asset Management
Luxembourg
$20.2M
5
Qube Research & Technologies (QRT)
5
Qube Research & Technologies (QRT)
United Kingdom
$19.9M

Top Sellers

1
PA
1
Perceptive Advisors
New York
$42.5M
2
RG
2
Redmile Group
California
$6.81M
3
American Century Companies
3
American Century Companies
Missouri
$0
4
NHAS
4
Novo Holdings A/S
Denmark
$0
5
JPMorgan Chase & Co
5
JPMorgan Chase & Co
New York
$12.7M
Name Holding Trade Value Shares
Change 		Shares
Change %
ECM
276
ExodusPoint Capital Management
New York
– -$2.71M -332,207 Closed
Ameriprise
277
Ameriprise
Minnesota
– -$2.33M -285,804 Closed
SC
278
Stempoint Capital
New York
– -$2.19M -268,919 Closed
State of New Jersey Common Pension Fund D
279
State of New Jersey Common Pension Fund D
New Jersey
– -$1.69M -207,121 Closed
BT
280
Banque Transatlantique
France
– -$1.26M -166,491 Closed
CF
281
Corebridge Financial
Texas
– -$1.17M -143,748 Closed
XT
282
XTX Topco
Cayman Islands
– -$871K -106,773 Closed
CAU
283
Caxton Associates (UK)
– -$474K -58,114 Closed
MF
284
Magnetar Financial
Illinois
– -$403K -49,393 Closed
Vontobel Holding
285
Vontobel Holding
Switzerland
– -$397K -48,683 Closed
PA
286
Procyon Advisors
Connecticut
– -$347K -42,576 Closed
ET
287
Entropy Technologies
New York
– -$317K -38,790 Closed
VF
288
Virtu Financial
New York
– -$233K -28,571 Closed
FCM
289
Fieldview Capital Management
Michigan
– -$231K -28,309 Closed
LCGC
290
Legacy Capital Group California
California
– -$220K -26,993 Closed
JG
291
Jain Global
New York
– -$195K -23,910 Closed
Nomura Holdings
292
Nomura Holdings
Japan
– -$181K -22,168 Closed
SCM
293
Semanteon Capital Management
Massachusetts
– -$177K -21,674 Closed
FRM
294
Fox Run Management
Connecticut
– -$175K -21,449 Closed
Los Angeles Capital Management
295
Los Angeles Capital Management
California
– -$167K -20,504 Closed
BCM
296
Bayesian Capital Management
New York
– -$162K -19,900 Closed
SP
297
SIH Partners
Delaware
– -$158K -19,364 Closed
BPC
298
Bryce Point Capital
New York
– -$111K -12,282 Closed
QCM
299
Quantinno Capital Management
New York
– -$95.6K -11,717 Closed
TSS
300
Two Sigma Securities
New York
– -$81.8K -10,021 Closed
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12
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