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Edgewise Therapeutics

223 hedge funds and large institutions have $4.82B invested in Edgewise Therapeutics in 2026 Q2 according to their latest regulatory filings, with 41 funds opening new positions, 83 increasing their positions, 72 reducing their positions, and 26 closing their positions.

New
Increased
Maintained
Reduced
Closed

94% more call options, than puts

Call options by funds: $17.6M | Put options by funds: $9.08M

58% more first-time investments, than exits

New positions opened: 41 | Existing positions closed: 26

29% more capital invested

Capital invested by funds: $3.72B → $4.82B (+$1.1B)

18% more funds holding in top 10

Funds holding in top 10: 1113 (+2)

15% more repeat investments, than reductions

Existing positions increased: 83 | Existing positions reduced: 72

4% more funds holding

Funds holding: 214223 (+9)

0.2% more ownership

Funds ownership: 110.5%110.7% (+0.2%)

Holders
223
Holders Change
+9
Holders Change %
+4.21%
% of All Funds
2.7%
Holding in Top 10
13
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+18.18%
% of All Funds
0.16%
New
41
Increased
83
Reduced
72
Closed
26
Calls
$17.6M
Puts
$9.08M
Net Calls
+$8.56M
Net Calls Change
+$900K
Name Holding Trade Value Shares
Change
Change in
Stake
BCI
151
Brinker Capital Investments
Pennsylvania
$282K +$16.6K +481 +7%
EGM
152
Engineers Gate Manager
New York
$271K +$230K +6,670 New
AIP
153
Ameritas Investment Partners
Nebraska
$264K +$29.4K +853 +15%
Pictet Asset Management
154
Pictet Asset Management
Switzerland
$255K -$46.3K -1,343 -18%
MG
155
Marex Group
$255K +$216K +6,274 New
Marshall Wace
156
Marshall Wace
United Kingdom
$248K -$22.1M -642,293 -99%
Rafferty Asset Management
157
Rafferty Asset Management
New York
$245K +$208K +6,035 New
FRM
158
Fox Run Management
Connecticut
$244K -$67.6K -1,962 -25%
Susquehanna International Group
159
Susquehanna International Group
Pennsylvania
$231K -$723K -20,982 -79%
Squarepoint
160
Squarepoint
New York
$230K +$195K +5,655 New
Teacher Retirement System of Texas
161
Teacher Retirement System of Texas
Texas
$226K -$39.6K -1,150 -17%
AC
162
AXQ Capital
New Jersey
$225K -$137K -3,976 -42%
Principal Financial Group
163
Principal Financial Group
Iowa
$222K +$189K +5,470 New
YIH
164
Y-Intercept (HK)
Hong Kong
$222K +$188K +5,466 New
PR
165
PSP Research
Pennsylvania
$203K -$51.7K -1,500 -23%
Mirae Asset Global Investments
166
Mirae Asset Global Investments
South Korea
$196K -$27K -783 -14%
Group One Trading
167
Group One Trading
Illinois
$182K +$154K +4,477 New
Royal Bank of Canada
168
Royal Bank of Canada
Ontario, Canada
$153K -$72.8K -2,111 -36%
US Bancorp
169
US Bancorp
Minnesota
$138K +$14.2K +413 +14%
Public Employees Retirement Association of Colorado
170
Public Employees Retirement Association of Colorado
Colorado
$116K
TRCT
171
Tower Research Capital (TRC)
New York
$114K -$91.7K -2,661 -49%
GFM
172
GF Fund Management
China
$92.3K -$3.65K -106 -4%
GI
173
GAMMA Investing
California
$85.6K -$6.27K -182 -8%
Acadian Asset Management
174
Acadian Asset Management
Massachusetts
$67K -$36.8K -1,068 -39%
KBC Group
175
KBC Group
Belgium
$63K

EWTX Hedge Fund Activity: Q2 2026 in Review

223 of the 8,274 institutional investors tracked by Wall St. Rank reported a position in Edgewise Therapeutics (EWTX) for Q2 2026, worth a combined $4.82B — up 29% from $3.72B a quarter earlier.

Buyers outnumbered sellers: 41 funds opened new EWTX positions and 26 closed out — a net gain of 15 holders — while 83 added to existing stakes and 72 trimmed.

The largest buyer was Fidelity Investments, adding an estimated $154M. The largest seller was Baker Bros. Advisors, cutting an estimated $99.1M.

  • 223 institutional investors held Edgewise Therapeutics (EWTX) as of Q2 2026, up from 214 in Q1 2026.
  • Funds reported $4.82B of Edgewise Therapeutics stock for Q2 2026, up 29% quarter-over-quarter.
  • 41 funds opened new Edgewise Therapeutics positions in Q2 2026 and 26 closed out, a net change of +15 holders.
  • The largest Edgewise Therapeutics buyer in Q2 2026 was Fidelity Investments, an estimated $154M added.
  • The largest Edgewise Therapeutics seller in Q2 2026 was Baker Bros. Advisors, an estimated $99.1M sold.

Based on aggregated 13F filings for Q2 2026.