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Edgewise Therapeutics
EWTX

223 hedge funds and large institutions have $4.82B invested in Edgewise Therapeutics in 2026 Q2 according to their latest regulatory filings, with 41 funds opening new positions, 83 increasing their positions, 72 reducing their positions, and 26 closing their positions.

New
Increased
Maintained
Reduced
Closed

94% more call options, than puts

Call options by funds: $17.6M | Put options by funds: $9.08M

58% more first-time investments, than exits

New positions opened: 41 | Existing positions closed: 26

29% more capital invested

Capital invested by funds: $3.72B → $4.82B (+$1.1B)

18% more funds holding in top 10

Funds holding in top 10: 11 → 13 (+2)

15% more repeat investments, than reductions

Existing positions increased: 83 | Existing positions reduced: 72

4% more funds holding

Funds holding: 214 → 223 (+9)

0.2% more ownership

Funds ownership: 110.5% → 110.7% (+0.2%)

Holders
223
Holders Change
+9
Holders Change %
+4.21%
% of All Funds
2.7%
Holding in Top 10
13
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+18.18%
% of All Funds
0.16%
New
41
Increased
83
Reduced
72
Closed
26
Calls
$17.6M
Puts
$9.08M
Net Calls
+$8.56M
Net Calls Change
+$900K

Top Buyers

Rank Fund Capital Flow
1
Fidelity Investments
Fidelity Investments
Massachusetts
+$154M
2
PBA
Paradigm Biocapital Advisors
New York
+$98.3M
3
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
+$25.8M
4
TCM
Tyro Capital Management
Florida
+$21.1M
5
Adage Capital Partners
Adage Capital Partners
Massachusetts
+$15.9M

Top Sellers

Rank Fund Capital Flow
1
BBA
Baker Bros. Advisors
New York
-$99.1M
2
RCM
RA Capital Management
Massachusetts
-$70.2M
3
BG
Bellevue Group
Switzerland
-$48.1M
4
SL
Siren LLC
Connecticut
-$42.9M
5
UBS Group
UBS Group
Switzerland
-$39.2M
Name Holding Trade Value Shares
Change 		Change in
Stake
SSA
51
Schonfeld Strategic Advisors
New York
$10.4M +$5.38M +156,127 +158%
Deutsche Bank
52
Deutsche Bank
Germany
$9.95M +$797K +23,127 +10%
DCM
53
DAFNA Capital Management
California
$9.22M +$3.95M +114,583 +102%
WP
54
Woodline Partners
California
$9.11M – – –
Bank of New York Mellon
55
Bank of New York Mellon
New York
$8.63M +$686K +19,913 +10%
JP Morgan Chase
56
JP Morgan Chase
New York
$8.48M +$1.92M +55,578 +38%
PCM
57
Peregrine Capital Management
Minnesota
$8.07M -$348K -10,102 -5%
SAM
58
SEB Asset Management
$7.88M -$429K -12,449 -6%
GIM
59
Granahan Investment Management
Massachusetts
$7.87M -$244K -7,065 -4%
Neuberger Berman Group
60
Neuberger Berman Group
New York
$7.77M +$776K +22,517 +13%
Barclays
61
Barclays
United Kingdom
$7.73M +$447K +12,961 +7%
D.E. Shaw & Co
62
D.E. Shaw & Co
New York
$7.68M +$2.9M +84,252 +80%
UBS Group
63
UBS Group
Switzerland
$7.11M -$39.2M -1,136,158 -87%
ACM
64
ADAR1 Capital Management
Texas
$5.82M +$1.81M +52,600 +58%
KCA
65
KVP Capital Advisors
California
$5.4M – – –
Invesco
66
Invesco
Georgia
$4.91M -$602K -17,467 -13%
UBS AM
67
UBS AM
Illinois
$4.8M +$120K +3,489 +3%
Point72 Asset Management
68
Point72 Asset Management
Connecticut
$4.76M +$4.04M +117,262 New
QPW
69
Quantum Private Wealth
Florida
$4.61M -$112K -3,244 -3%
AA
70
ALPS Advisors
Colorado
$4.42M +$740K +21,469 +25%
MAP
71
Moody Aldrich Partners
Massachusetts
$4.26M -$317K -9,189 -8%
AGP
72
Artia Global Partners
Florida
$4.01M +$1.15M +33,300 +51%
Swiss National Bank
73
Swiss National Bank
Switzerland
$3.93M -$245K -7,100 -7%
VOYA Investment Management
74
VOYA Investment Management
Georgia
$3.85M +$1.91M +55,518 +142%
HSBC Holdings
75
HSBC Holdings
United Kingdom
$3.72M +$3.16M +91,638 New
1 2
3
4 5

EWTX Hedge Fund Activity: Q2 2026 in Review

223 of the 8,274 institutional investors tracked by Wall St. Rank reported a position in Edgewise Therapeutics (EWTX) for Q2 2026, worth a combined $4.82B — up 29% from $3.72B a quarter earlier.

Buyers outnumbered sellers: 41 funds opened new EWTX positions and 26 closed out — a net gain of 15 holders — while 83 added to existing stakes and 72 trimmed.

The largest buyer was Fidelity Investments, adding an estimated $154M. The largest seller was Baker Bros. Advisors, cutting an estimated $99.1M.

  • 223 institutional investors held Edgewise Therapeutics (EWTX) as of Q2 2026, up from 214 in Q1 2026.
  • Funds reported $4.82B of Edgewise Therapeutics stock for Q2 2026, up 29% quarter-over-quarter.
  • 41 funds opened new Edgewise Therapeutics positions in Q2 2026 and 26 closed out, a net change of +15 holders.
  • The largest Edgewise Therapeutics buyer in Q2 2026 was Fidelity Investments, an estimated $154M added.
  • The largest Edgewise Therapeutics seller in Q2 2026 was Baker Bros. Advisors, an estimated $99.1M sold.

Based on aggregated 13F filings for Q2 2026.