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Edgewise Therapeutics
EWTX

223 hedge funds and large institutions have $4.82B invested in Edgewise Therapeutics in 2026 Q2 according to their latest regulatory filings, with 41 funds opening new positions, 83 increasing their positions, 72 reducing their positions, and 26 closing their positions.

New
Increased
Maintained
Reduced
Closed

94% more call options, than puts

Call options by funds: $17.6M | Put options by funds: $9.08M

58% more first-time investments, than exits

New positions opened: 41 | Existing positions closed: 26

29% more capital invested

Capital invested by funds: $3.72B → $4.82B (+$1.1B)

18% more funds holding in top 10

Funds holding in top 10: 11 → 13 (+2)

15% more repeat investments, than reductions

Existing positions increased: 83 | Existing positions reduced: 72

4% more funds holding

Funds holding: 214 → 223 (+9)

0.2% more ownership

Funds ownership: 110.5% → 110.7% (+0.2%)

Holders
223
Holders Change
+9
Holders Change %
+4.21%
% of All Funds
2.7%
Holding in Top 10
13
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+18.18%
% of All Funds
0.16%
New
41
Increased
83
Reduced
72
Closed
26
Calls
$17.6M
Puts
$9.08M
Net Calls
+$8.56M
Net Calls Change
+$900K

Top Buyers

Rank Fund Capital Flow
1
Fidelity Investments
Fidelity Investments
Massachusetts
+$154M
2
PBA
Paradigm Biocapital Advisors
New York
+$98.3M
3
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
+$25.8M
4
TCM
Tyro Capital Management
Florida
+$21.1M
5
Adage Capital Partners
Adage Capital Partners
Massachusetts
+$15.9M

Top Sellers

Rank Fund Capital Flow
1
BBA
Baker Bros. Advisors
New York
-$99.1M
2
RCM
RA Capital Management
Massachusetts
-$70.2M
3
BG
Bellevue Group
Switzerland
-$48.1M
4
SL
Siren LLC
Connecticut
-$42.9M
5
UBS Group
UBS Group
Switzerland
-$39.2M
Name Holding Trade Value Shares
Change 		Change in
Stake
Millennium Management
226
Millennium Management
New York
– -$10.8M -342,867 Closed
SC
227
Stempoint Capital
New York
– -$9.16M -290,864 Closed
SCM
228
Sio Capital Management
New York
– -$8.47M -268,986 Closed
Ameriprise
229
Ameriprise
Minnesota
– -$6.32M -200,661 Closed
EAM
230
Eventide Asset Management
Massachusetts
– -$4.72M -149,863 Closed
FGP
231
Freestone Grove Partners
California
– -$4.68M -148,426 Closed
Schroder Investment Management Group
232
Schroder Investment Management Group
United Kingdom
– -$4.4M -145,286 Closed
II
233
Ishara Investments
California
– -$1.55M -49,200 Closed
JG
234
Jain Global
New York
– -$1.46M -46,401 Closed
SCM
235
Silverarc Capital Management
Massachusetts
– -$1.34M -42,615 Closed
CM
236
Caption Management
Oklahoma
– -$1.33M -38,675 Closed
HT
237
Headlands Technologies
Illinois
– -$434K -13,767 Closed
Hudson Bay Capital Management
238
Hudson Bay Capital Management
Connecticut
– -$407K -12,930 Closed
SFCM
239
Seven Fleet Capital Management
California
– -$369K -11,701 Closed
EC
240
Elmind Capital
New York
– -$315K -10,000 Closed
SWA
241
SFMG Wealth Advisors
Texas
– -$315K -10,000 Closed
AI
242
Atom Investors
Texas
– -$313K -9,941 Closed
SG Americas Securities
243
SG Americas Securities
New York
– -$120K -3,804 Closed
Simplex Trading
244
Simplex Trading
Illinois
– -$63.2K -1,832 Closed
WCM
245
Winthrop Capital Management
Indiana
– -$43K -1,377 Closed
SSG
246
Summit Securities Group
New York
– -$21.4K -678 Closed
EB
247
Eastern Bank
Massachusetts
– -$7.03K -223 Closed
MCM
248
MAI Capital Management
Ohio
– -$284 -9 Closed
QCG
249
Quadrant Capital Group
Ohio
– -$189 -6 Closed
6 7 8 9
10

EWTX Hedge Fund Activity: Q2 2026 in Review

223 of the 8,274 institutional investors tracked by Wall St. Rank reported a position in Edgewise Therapeutics (EWTX) for Q2 2026, worth a combined $4.82B — up 29% from $3.72B a quarter earlier.

Buyers outnumbered sellers: 41 funds opened new EWTX positions and 26 closed out — a net gain of 15 holders — while 83 added to existing stakes and 72 trimmed.

The largest buyer was Fidelity Investments, adding an estimated $154M. The largest seller was Baker Bros. Advisors, cutting an estimated $99.1M.

  • 223 institutional investors held Edgewise Therapeutics (EWTX) as of Q2 2026, up from 214 in Q1 2026.
  • Funds reported $4.82B of Edgewise Therapeutics stock for Q2 2026, up 29% quarter-over-quarter.
  • 41 funds opened new Edgewise Therapeutics positions in Q2 2026 and 26 closed out, a net change of +15 holders.
  • The largest Edgewise Therapeutics buyer in Q2 2026 was Fidelity Investments, an estimated $154M added.
  • The largest Edgewise Therapeutics seller in Q2 2026 was Baker Bros. Advisors, an estimated $99.1M sold.

Based on aggregated 13F filings for Q2 2026.