We are live on ! Find out more
ETNB

89bio
ETNB

Delisted

ETNB was delisted on the 29th of October, 2025.

Back to rankings

186 hedge funds and large institutions have $1.14B invested in 89bio in 2025 Q1 according to their latest regulatory filings, with 53 funds opening new positions, 91 increasing their positions, 33 reducing their positions, and 22 closing their positions.

New
Increased
Maintained
Reduced
Closed

176% more repeat investments, than reductions

Existing positions increased: 91 | Existing positions reduced: 33

141% more first-time investments, than exits

New positions opened: 53 | Existing positions closed: 22

50% more funds holding in top 10

Funds holding in top 10: 2 → 3 (+1)

20% more capital invested

Capital invested by funds: $949M → $1.14B (+$190M)

20% more funds holding

Funds holding: 155 → 186 (+31)

2.59% more ownership

Funds ownership: 103.14% → 105.72% (+2.6%)

60% less call options, than puts

Call options by funds: $3.12M | Put options by funds: $7.7M

Holders
186
Holders Change
+31
Holders Change %
+20%
% of All Funds
2.49%
Holding in Top 10
3
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+50%
% of All Funds
0.04%
New
53
Increased
91
Reduced
33
Closed
22
Calls
$3.12M
Puts
$7.7M
Net Calls
-$4.59M
Net Calls Change
+$2.92M

Top Buyers

Rank Fund Capital Flow
1
RCM
RA Capital Management
Massachusetts
+$50M
2
SCM
Suvretta Capital Management
New York
+$36.1M
3
Janus Henderson Group
Janus Henderson Group
United Kingdom
+$34.5M
4
DTC
Deep Track Capital
Connecticut
+$24.8M
5
LGM
Logos Global Management
California
+$21.9M

Top Sellers

Rank Fund Capital Flow
1
RI
RTW Investments
New York
-$48.2M
2
BI
BVF Inc
California
-$33.9M
3
FLSM
Frazier Life Sciences Management
California
-$7.82M
4
AllianceBernstein
AllianceBernstein
Tennessee
-$7.77M
5
Balyasny Asset Management
Balyasny Asset Management
Illinois
-$5.97M
Name Holding Trade Value Shares
Change 		Change in
Stake
Balyasny Asset Management
51
Balyasny Asset Management
Illinois
$2.45M -$5.97M -682,800 -67%
ACA
52
Apis Capital Advisors
New York
$2.29M +$2.75M +315,000 New
HCA
53
Harbor Capital Advisors
Illinois
$2.29M +$550K +62,874 +25%
Bank of New York Mellon
54
Bank of New York Mellon
New York
$2.25M +$540K +61,760 +25%
EP
55
Eversept Partners
New York
$2.21M +$2.66M +303,731 New
LCM
56
Laurion Capital Management
New York
$2.13M -$4.27M -487,806 -63%
UBS AM
57
UBS AM
Illinois
$1.95M +$788K +90,107 +50%
SFI
58
Susquehanna Fundamental Investments
Pennsylvania
$1.94M +$1.8M +205,474 +337%
Comerica Bank
59
Comerica Bank
Texas
$1.88M +$13.5K +1,540 +0.6%
Hudson Bay Capital Management
60
Hudson Bay Capital Management
Connecticut
$1.82M +$2.19M +250,200 New
Wellington Management Group
61
Wellington Management Group
Massachusetts
$1.82M -$740K -84,612 -25%
DP
62
Diadema Partners
New Jersey
$1.68M +$2.02M +231,436 New
RA
63
Royce & Associates
New York
$1.64M +$1.98M +226,050 New
FMI
64
F/M Investments
District of Columbia
$1.56M +$1.88M +214,837 New
Citigroup
65
Citigroup
New York
$1.51M +$829K +94,789 +84%
Swiss National Bank
66
Swiss National Bank
Switzerland
$1.49M +$384K +43,900 +27%
UBS Group
67
UBS Group
Switzerland
$1.48M +$787K +90,022 +80%
NM
68
Newtyn Management
New York
$1.45M -$350K -40,000 -17%
Two Sigma Investments
69
Two Sigma Investments
New York
$1.37M -$429K -49,072 -21%
AG
70
Algert Global
California
$1.36M +$13.8K +1,584 +0.9%
American Century Companies
71
American Century Companies
Missouri
$1.35M +$627K +71,726 +63%
JFG
72
Jefferies Financial Group
New York
$1.32M +$276K +31,604 +21%
CM
73
Caption Management
Oklahoma
$1.31M -$750K -85,762 -32%
Qube Research & Technologies (QRT)
74
Qube Research & Technologies (QRT)
United Kingdom
$1.29M +$1.55M +176,834 New
AAA
75
Affinity Asset Advisors
New York
$1.27M +$1.53M +175,000 New
1 2
3
4 5

ETNB Hedge Fund Activity: Q1 2025 in Review

186 of the 7,459 institutional investors tracked by Wall St. Rank reported a position in 89bio (ETNB) for Q1 2025, worth a combined $1.14B — up 20% from $949M a quarter earlier.

Buyers outnumbered sellers: 53 funds opened new ETNB positions and 22 closed out — a net gain of 31 holders — while 91 added to existing stakes and 33 trimmed.

The largest buyer was RA Capital Management, adding an estimated $50M. The largest seller was RTW Investments, cutting an estimated $48.2M.

  • 186 institutional investors held 89bio (ETNB) as of Q1 2025, up from 155 in Q4 2024.
  • Funds reported $1.14B of 89bio stock for Q1 2025, up 20% quarter-over-quarter.
  • 53 funds opened new 89bio positions in Q1 2025 and 22 closed out, a net change of +31 holders.
  • The largest 89bio buyer in Q1 2025 was RA Capital Management, an estimated $50M added.
  • The largest 89bio seller in Q1 2025 was RTW Investments, an estimated $48.2M sold.

Based on aggregated 13F filings for Q1 2025.