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ETNB

89bio

Delisted

ETNB was delisted on the 29th of October, 2025.

186 hedge funds and large institutions have $1.14B invested in 89bio in 2025 Q1 according to their latest regulatory filings, with 53 funds opening new positions, 91 increasing their positions, 33 reducing their positions, and 22 closing their positions.

New
Increased
Maintained
Reduced
Closed

176% more repeat investments, than reductions

Existing positions increased: 91 | Existing positions reduced: 33

141% more first-time investments, than exits

New positions opened: 53 | Existing positions closed: 22

50% more funds holding in top 10

Funds holding in top 10: 23 (+1)

20% more capital invested

Capital invested by funds: $949M → $1.14B (+$190M)

20% more funds holding

Funds holding: 155186 (+31)

2.59% more ownership

Funds ownership: 103.14%105.72% (+2.6%)

60% less call options, than puts

Call options by funds: $3.12M | Put options by funds: $7.7M

Holders
186
Holders Change
+31
Holders Change %
+20%
% of All Funds
2.49%
Holding in Top 10
3
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+50%
% of All Funds
0.04%
New
53
Increased
91
Reduced
33
Closed
22
Calls
$3.12M
Puts
$7.7M
Net Calls
-$4.59M
Net Calls Change
+$2.92M
Name Holding Trade Value Shares
Change
Change in
Stake
Janus Henderson Group
1
Janus Henderson Group
United Kingdom
$165M +$34.5M +3,948,849 +24%
RCM
2
RA Capital Management
Massachusetts
$145M +$50M +5,714,285 +40%
SCM
3
Suvretta Capital Management
New York
$104M +$36.1M +4,132,548 +41%
BlackRock
4
BlackRock
New York
$73.2M +$19.1M +2,185,245 +28%
DTC
5
Deep Track Capital
Connecticut
$67.7M +$24.8M +2,838,084 +44%
Vanguard Group
6
Vanguard Group
Pennsylvania
$52.1M +$12.9M +1,471,278 +26%
ACA
7
Avoro Capital Advisors
New York
$46.2M +$19.7M +2,250,000 +55%
Citadel Advisors
8
Citadel Advisors
Florida
$37M +$3.12M +356,984 +8%
Pictet Asset Management
9
Pictet Asset Management
Switzerland
$30.6M +$10.5M +1,197,853 +40%
State Street
10
State Street
Massachusetts
$29.3M +$9.49M +1,085,075 +37%
Westfield Capital Management
11
Westfield Capital Management
Massachusetts
$28.3M +$69.5K +7,947 +0.2%
Geode Capital Management
12
Geode Capital Management
Massachusetts
$21.1M +$6.04M +690,366 +31%
LGM
13
Logos Global Management
California
$18.2M +$21.9M +2,500,000 New
PCH
14
Polar Capital Holdings
United Kingdom
$18.2M +$21.9M +2,500,000 New
RI
15
RTW Investments
New York
$14.3M -$48.2M -5,510,534 -74%
RG
16
Redmile Group
California
$13.7M -$2.45M -280,732 -13%
BBL
17
Beck Bode LLC
Massachusetts
$13.2M +$15.9M +1,815,524 New
EA
18
Emerald Advisers
Pennsylvania
$11.3M +$13.6M +1,550,671 New
SCM
19
Silverarc Capital Management
Massachusetts
$11M +$12.4M +1,413,987 +1,465%
UOWF
20
University of Wisconsin Foundation
Wisconsin
$8.38M +$2.06M +236,000 +26%
Northern Trust
21
Northern Trust
Illinois
$7.89M +$2.02M +230,677 +27%
EMFAT
22
Emerald Mutual Fund Advisers Trust
Pennsylvania
$7.87M +$9.47M +1,082,973 New
IHAM
23
Integral Health Asset Management
New York
$7.63M +$437K +50,000 +5%
N
24
Nuveen
North Carolina
$7.53M +$6.55M +749,465 +262%
Goldman Sachs
25
Goldman Sachs
New York
$7.24M +$1.65M +188,367 +23%

ETNB Hedge Fund Activity: Q1 2025 in Review

186 of the 7,459 institutional investors tracked by Wall St. Rank reported a position in 89bio (ETNB) for Q1 2025, worth a combined $1.14B — up 20% from $949M a quarter earlier.

Buyers outnumbered sellers: 53 funds opened new ETNB positions and 22 closed out — a net gain of 31 holders — while 91 added to existing stakes and 33 trimmed.

The largest buyer was RA Capital Management, adding an estimated $50M. The largest seller was RTW Investments, cutting an estimated $48.2M.

  • 186 institutional investors held 89bio (ETNB) as of Q1 2025, up from 155 in Q4 2024.
  • Funds reported $1.14B of 89bio stock for Q1 2025, up 20% quarter-over-quarter.
  • 53 funds opened new 89bio positions in Q1 2025 and 22 closed out, a net change of +31 holders.
  • The largest 89bio buyer in Q1 2025 was RA Capital Management, an estimated $50M added.
  • The largest 89bio seller in Q1 2025 was RTW Investments, an estimated $48.2M sold.

Based on aggregated 13F filings for Q1 2025.