We are live on ! Find out more
ETNB

89bio

Delisted

ETNB was delisted on the 29th of October, 2025.

153 hedge funds and large institutions have $1.07B invested in 89bio in 2023 Q4 according to their latest regulatory filings, with 33 funds opening new positions, 70 increasing their positions, 41 reducing their positions, and 40 closing their positions.

New
Increased
Maintained
Reduced
Closed

71% more repeat investments, than reductions

Existing positions increased: 70 | Existing positions reduced: 41

10.04% more ownership

Funds ownership: 95.34%105.38% (+10%)

4% less capital invested

Capital invested by funds: $1.11B → $1.07B (-$42.6M)

4% less funds holding

Funds holding: 160153 (-7)

18% less first-time investments, than exits

New positions opened: 33 | Existing positions closed: 40

49% less call options, than puts

Call options by funds: $8.29M | Put options by funds: $16.2M

50% less funds holding in top 10

Funds holding in top 10: 42 (-2)

Holders
153
Holders Change
-7
Holders Change %
-4.38%
% of All Funds
2.23%
Holding in Top 10
2
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-50%
% of All Funds
0.03%
New
33
Increased
70
Reduced
41
Closed
40
Calls
$8.29M
Puts
$16.2M
Net Calls
-$7.89M
Net Calls Change
-$35.4M
Name Holding Trade Value Shares
Change
Change in
Stake
RCM
1
RA Capital Management
Massachusetts
$128M
Janus Henderson Group
2
Janus Henderson Group
United Kingdom
$99.6M +$44.9M +4,885,938 +121%
RI
3
RTW Investments
New York
$62.3M +$51.3M +5,578,931 New
BlackRock
4
BlackRock
New York
$60.9M +$4.49M +487,956 +10%
State Street
5
State Street
Massachusetts
$60.3M +$10M +1,092,718 +25%
SCM
6
Suvretta Capital Management
New York
$54.6M +$20.2M +2,194,030 +81%
Pictet Asset Management
7
Pictet Asset Management
Switzerland
$50.9M +$6.16M +669,726 +17%
Vanguard Group
8
Vanguard Group
Pennsylvania
$48.1M +$7.19M +781,803 +22%
BI
9
BVF Inc
California
$45.2M +$20.2M +2,201,200 +119%
Holocene Advisors
10
Holocene Advisors
New York
$39M +$11.5M +1,254,823 +56%
Adage Capital Partners
11
Adage Capital Partners
Massachusetts
$34.9M +$13.1M +1,426,583 +84%
Morgan Stanley
12
Morgan Stanley
New York
$33.3M +$21.9M +2,378,766 +397%
LCM
13
Laurion Capital Management
New York
$30.2M +$13.8M +1,498,564 +124%
Citadel Advisors
14
Citadel Advisors
Florida
$24.3M +$6.2M +674,330 +45%
FLSM
15
Frazier Life Sciences Management
California
$22.3M +$18.4M +2,000,000 New
RG
16
Redmile Group
California
$22M +$11.1M +1,207,447 +158%
Federated Hermes
17
Federated Hermes
Pennsylvania
$21.9M -$1.54M -167,035 -8%
Westfield Capital Management
18
Westfield Capital Management
Massachusetts
$19.7M +$4.13M +449,262 +34%
Geode Capital Management
19
Geode Capital Management
Massachusetts
$15.4M +$770K +83,722 +6%
SCM
20
Superstring Capital Management
New York
$11.4M +$9.39M +1,021,477 New
Franklin Resources
21
Franklin Resources
California
$9.25M +$2.94K +320 +0%
OCM
22
Orchard Capital Management
Illinois
$8.26M +$1.8M +196,329 +36%
EAM
23
Eagle Asset Management
Florida
$7.84M -$99.3K -10,803 -2%
Goldman Sachs
24
Goldman Sachs
New York
$7.05M +$1.03M +112,438 +22%
Northern Trust
25
Northern Trust
Illinois
$6.9M +$343K +37,339 +6%

ETNB Hedge Fund Activity: Q4 2023 in Review

153 of the 6,860 institutional investors tracked by Wall St. Rank reported a position in 89bio (ETNB) for Q4 2023, worth a combined $1.07B — down 3.8% from $1.11B a quarter earlier.

Sellers outnumbered buyers: 40 funds closed out of ETNB and 33 opened new positions — a net loss of 7 holders — while 41 trimmed existing stakes and 70 added.

The largest buyer was RTW Investments, opening a new position worth an estimated $51.3M. The largest seller was Braidwell, exiting entirely with an estimated $24.6M sold.

  • 153 institutional investors held 89bio (ETNB) as of Q4 2023, down from 160 in Q3 2023.
  • Funds reported $1.07B of 89bio stock for Q4 2023, down 3.8% quarter-over-quarter.
  • 33 funds opened new 89bio positions in Q4 2023 and 40 closed out, a net change of -7 holders.
  • The largest 89bio buyer in Q4 2023 was RTW Investments, an estimated $51.3M added.
  • The largest 89bio seller in Q4 2023 was Braidwell, an estimated $24.6M sold.

Based on aggregated 13F filings for Q4 2023.