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ETNB

89bio

Delisted

ETNB was delisted on the 29th of October, 2025.

198 hedge funds and large institutions have $2.27B invested in 89bio in 2025 Q3 according to their latest regulatory filings, with 57 funds opening new positions, 58 increasing their positions, 63 reducing their positions, and 41 closing their positions.

New
Increased
Maintained
Reduced
Closed

175% more funds holding in top 10

Funds holding in top 10: 411 (+7)

44% more capital invested

Capital invested by funds: $1.58B → $2.27B (+$690M)

39% more first-time investments, than exits

New positions opened: 57 | Existing positions closed: 41

8% more funds holding

Funds holding: 184198 (+14)

8% less repeat investments, than reductions

Existing positions increased: 58 | Existing positions reduced: 63

6.12% less ownership

Funds ownership: 110.42%104.3% (-6.1%)

80% less call options, than puts

Call options by funds: $20.3M | Put options by funds: $101M

Holders
198
Holders Change
+14
Holders Change %
+7.61%
% of All Funds
2.6%
Holding in Top 10
11
Holding in Top 10 Change
+7
Holding in Top 10 Change %
+175%
% of All Funds
0.14%
New
57
Increased
58
Reduced
63
Closed
41
Calls
$20.3M
Puts
$101M
Net Calls
-$80.9M
Net Calls Change
-$67.2M
Name Holding Trade Value Shares
Change
Change in
Stake
RCM
1
RA Capital Management
Massachusetts
$292M
PCM
2
Pentwater Capital Management
Florida
$173M +$120M +11,750,000 New
BlackRock
3
BlackRock
New York
$152M -$2.58M -253,031 -2%
DTC
4
Deep Track Capital
Connecticut
$138M -$1.47M -143,829 -2%
Adage Capital Partners
5
Adage Capital Partners
Massachusetts
$134M +$72.7M +7,128,587 +362%
SCM
6
Suvretta Capital Management
New York
$122M -$60.4M -5,930,000 -42%
Vanguard Group
7
Vanguard Group
Pennsylvania
$118M -$1.92M -188,695 -2%
ACA
8
Avoro Capital Advisors
New York
$93.9M -$3.69M -362,210 -5%
GCL
9
Glazer Capital LLC
New York
$82.9M +$57.5M +5,636,905 New
Janus Henderson Group
10
Janus Henderson Group
United Kingdom
$79.1M -$157M -15,410,178 -74%
State Street
11
State Street
Massachusetts
$77.7M +$10.6M +1,036,351 +24%
Deutsche Bank
12
Deutsche Bank
Germany
$51.4M +$34.8M +3,413,036 +3,942%
Westfield Capital Management
13
Westfield Capital Management
Massachusetts
$48.4M -$810K -79,448 -2%
Geode Capital Management
14
Geode Capital Management
Massachusetts
$45.5M -$193K -18,959 -0.6%
SCS
15
Syquant Capital SAS
France
$38.1M +$26.4M +2,593,694 New
KC
16
Kryger Capital
United Kingdom
$34.5M +$24M +2,350,000 New
TAL
17
TIG Advisors LLC
New York
$32.1M +$22.3M +2,186,648 New
Hudson Bay Capital Management
18
Hudson Bay Capital Management
Connecticut
$31.9M +$19.8M +1,946,300 +862%
ACM
19
ADAR1 Capital Management
Texas
$31.1M +$12.6M +1,237,170 +141%
Goldman Sachs
20
Goldman Sachs
New York
$23.8M +$3.71M +363,700 +29%
Dimensional Fund Advisors
21
Dimensional Fund Advisors
Texas
$23.6M +$4.32M +423,560 +36%
RG
22
Redmile Group
California
$21.7M -$735K -72,072 -5%
Balyasny Asset Management
23
Balyasny Asset Management
Illinois
$21.4M +$14.9M +1,459,055 New
WAM
24
Weiss Asset Management
Massachusetts
$20.6M +$14.3M +1,400,000 New
Northern Trust
25
Northern Trust
Illinois
$16.5M -$67.8K -6,653 -0.6%

ETNB Hedge Fund Activity: Q3 2025 in Review

198 of the 7,621 institutional investors tracked by Wall St. Rank reported a position in 89bio (ETNB) for Q3 2025, worth a combined $2.27B — up 44% from $1.58B a quarter earlier.

Buyers outnumbered sellers: 57 funds opened new ETNB positions and 41 closed out — a net gain of 16 holders — while 58 added to existing stakes and 63 trimmed.

The largest buyer was Pentwater Capital Management, opening a new position worth an estimated $120M. The largest seller was Janus Henderson Group, cutting an estimated $157M.

  • 198 institutional investors held 89bio (ETNB) as of Q3 2025, up from 184 in Q2 2025.
  • Funds reported $2.27B of 89bio stock for Q3 2025, up 44% quarter-over-quarter.
  • 57 funds opened new 89bio positions in Q3 2025 and 41 closed out, a net change of +16 holders.
  • The largest 89bio buyer in Q3 2025 was Pentwater Capital Management, an estimated $120M added.
  • The largest 89bio seller in Q3 2025 was Janus Henderson Group, an estimated $157M sold.

Based on aggregated 13F filings for Q3 2025.