89bio
ETNB
ETNB was delisted on the 29th of October, 2025.
106 hedge funds and large institutions have $589M invested in 89bio in 2022 Q4 according to their latest regulatory filings, with 39 funds opening new positions, 33 increasing their positions, 20 reducing their positions, and 18 closing their positions.
579% more call options, than puts
Call options by funds: $5.79M | Put options by funds: $852K
180% more capital invested
Capital invested by funds: $210M → $589M (+$378M)
117% more first-time investments, than exits
New positions opened: 39 | Existing positions closed: 18
65% more repeat investments, than reductions
Existing positions increased: 33 | Existing positions reduced: 20
23% more funds holding
Funds holding: 86 → 106 (+20)
2.99% less ownership
Funds ownership: 102.48% → 99.5% (-3%)
100% less funds holding in top 10
Funds holding in top 10: 1 → 0 (-1)
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
CAM
Cormorant Asset Management
Boston,
Massachusetts
|
+$22.9M |
| 2 |
Holocene Advisors
New York
|
+$17.1M |
| 3 |
DTC
Deep Track Capital
Greenwich,
Connecticut
|
+$10.9M |
| 4 |
RCM
RA Capital Management
Boston,
Massachusetts
|
+$10.6M |
| 5 |
Marshall Wace
London,
United Kingdom
|
+$9.34M |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
BI
BVF Inc
San Francisco,
California
|
-$18.2M |
| 2 |
RCMNY
Rubric Capital Management (New York)
New York
|
-$5.73M |
| 3 |
GPP
Great Point Partners
Greenwich,
Connecticut
|
-$5.53M |
| 4 |
Janus Henderson Group
London,
United Kingdom
|
-$5.01M |
| 5 |
SFM
Sphera Funds Management
Tel Aviv,
Israel
|
-$4.3M |
ETNB Hedge Fund Activity: Q4 2022 in Review
106 of the 6,222 institutional investors tracked by Wall St. Rank reported a position in 89bio (ETNB) for Q4 2022, worth a combined $589M — up 180% from $210M a quarter earlier.
Buyers outnumbered sellers: 39 funds opened new ETNB positions and 18 closed out — a net gain of 21 holders — while 33 added to existing stakes and 20 trimmed.
The largest buyer was Cormorant Asset Management, opening a new position worth an estimated $22.9M. The largest seller was BVF Inc, exiting entirely with an estimated $18.2M sold.
- 106 institutional investors held 89bio (ETNB) as of Q4 2022, up from 86 in Q3 2022.
- Funds reported $589M of 89bio stock for Q4 2022, up 180% quarter-over-quarter.
- 39 funds opened new 89bio positions in Q4 2022 and 18 closed out, a net change of +21 holders.
- The largest 89bio buyer in Q4 2022 was Cormorant Asset Management, an estimated $22.9M added.
- The largest 89bio seller in Q4 2022 was BVF Inc, an estimated $18.2M sold.
Based on aggregated 13F filings for Q4 2022.