Two Sigma Investments
ETNB

Two Sigma Investments’s 89bio ETNB Stock Holding History

Two Sigma Investments’s Portfolio ETNB Stock Details ETNB Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2025
Q3 		– Sell
-254,109
Closed -$2.5M – 3715
2025
Q2 		$2.5M Buy
254,109
+65,660
+35% +$544K ﹤0.01% 1678
2025
Q1 		$1.37M Sell
188,449
-49,072
-21% -$429K ﹤0.01% 1985
2024
Q4 		$1.86M Sell
237,521
-131,167
-36% -$1.08M ﹤0.01% 1770
2024
Q3 		$2.73M Sell
368,688
-165,029
-31% -$1.39M 0.01% 1484
2024
Q2 		$4.28M Buy
533,717
+287,617
+117% +$2.57M 0.01% 1079
2024
Q1 		$2.86M Buy
246,100
+117,342
+91% +$1.3M 0.01% 1255
2023
Q4 		$1.44M Sell
128,758
-83,019
-39% -$763K ﹤0.01% 1848
2023
Q3 		$3.27M Sell
211,777
-420,908
-67% -$7.07M 0.01% 1108
2023
Q2 		$12M Sell
632,685
-235,276
-27% -$4.13M 0.03% 568
2023
Q1 		$13.2M Buy
867,961
+153,796
+22% +$2.01M 0.04% 489
2022
Q4 		$9.09M Buy
714,165
+224,641
+46% +$2.02M 0.03% 597
2022
Q3 		$2.83M Buy
489,524
+332,610
+212% +$1.46M 0.01% 995
2022
Q2 		$505K Sell
156,914
-63,504
-29% -$192K ﹤0.01% 1823
2022
Q1 		$831K Buy
220,418
+162,763
+282% +$1.05M ﹤0.01% 1794
2021
Q4 		$754K Sell
57,655
-19,401
-25% -$307K ﹤0.01% 2822
2021
Q3 		$1.51M Sell
77,056
-24,227
-24% -$443K ﹤0.01% 2236
2021
Q2 		$1.89M Sell
101,283
-56,893
-36% -$1.27M ﹤0.01% 1915
2021
Q1 		$3.75M Sell
158,176
-10,205
-6% -$236K 0.01% 1253
2020
Q4 		$4.1M Buy
168,381
+111,821
+198% +$2.86M 0.01% 1045
2020
Q3 		$1.45M Buy
+56,560
New +$1.79M 0.01% 1514

Other funds holding ETNB

RCM
RA Capital Management Boston, Massachusetts $9.44B AUM 157.3% 1-Year Est. Return
PCM
Pentwater Capital Management Naples, Florida $19.3B AUM 58.13% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
DTC
Deep Track Capital Greenwich, Connecticut $6.12B AUM 144% 1-Year Est. Return
Adage Capital Partners
Adage Capital Partners Boston, Massachusetts $64.8B AUM 42.7% 1-Year Est. Return
SCM
Suvretta Capital Management New York $3.92B AUM 86.67% 1-Year Est. Return
Vanguard Group
Vanguard Group Malvern, Pennsylvania $6.9T AUM 27.45% 1-Year Est. Return
ACA
Avoro Capital Advisors New York $10.2B AUM 149.19% 1-Year Est. Return
GCL
Glazer Capital LLC New York $4.71B AUM 81.93% 1-Year Est. Return
Janus Henderson Group
Janus Henderson Group London, United Kingdom $209B AUM 37.72% 1-Year Est. Return

Two Sigma Investments's ETNB Position: Q3 2025 in Review

Two Sigma Investments sold out of 89bio (ETNB) in Q3 2025, closing a stake of 254,109 shares — an estimated $2.5M sold.

Two Sigma Investments first reported a position in ETNB in Q3 2020 and held it in 20 quarters. The position peaked at $13.2M in Q1 2023. 198 funds tracked by Wall St. Rank hold ETNB as of Q3 2025.

  • Two Sigma Investments reported no remaining 89bio position as of Q3 2025 after selling out during the quarter.
  • Two Sigma Investments sold 254,109 89bio shares in Q3 2025, an estimated $2.5M.
  • Two Sigma Investments first reported a position in 89bio in Q3 2020 and held it in 20 quarters.
  • Two Sigma Investments's 89bio position peaked at $13.2M in Q1 2023.
  • 198 funds tracked by Wall St. Rank held 89bio as of Q3 2025.

Based on Two Sigma Investments's 13F filing for Q3 2025, filed 14 Nov 2025.