|
1
|
T. Rowe Price Investment Management
Baltimore,
Maryland
|
$558M
|
+$228M
|
+13,245,712
|
+76%
|
|
|
2
|
Janus Henderson Group
London,
|
$247M
|
-$4.14M
|
-240,346
|
-2%
|
|
|
3
|
|
$212M
|
+$8.78M
|
+509,032
|
+5%
|
|
|
4
|
Atlas Venture Life Science Advisors
Cambridge,
Massachusetts
|
$166M
|
–
|
–
|
–
|
|
|
5
|
Fidelity Investments
Boston,
Massachusetts
|
$162M
|
+$40.3M
|
+2,339,059
|
+36%
|
|
|
6
|
Orbis Allan Gray
Hamilton,
Bermuda
|
$123M
|
+$33.8M
|
+1,960,303
|
+41%
|
|
|
7
|
State Street
Boston,
Massachusetts
|
$121M
|
-$672K
|
-38,999
|
-0.6%
|
|
|
8
|
Vanguard Capital Management
Malvern,
Pennsylvania
|
$116M
|
+$110M
|
+6,405,069
|
New
|
|
|
9
|
Perceptive Advisors
New York
|
$84.6M
|
+$20.5M
|
+1,189,895
|
+34%
|
|
|
10
|
FCPM III Services
Naarden,
Netherlands
|
$84.2M
|
-$14.1M
|
-818,460
|
-15%
|
|
|
11
|
TCG Crossover Management
Palo Alto,
California
|
$83.7M
|
–
|
–
|
–
|
|
|
12
|
Vanguard Portfolio Management
Malvern,
Pennsylvania
|
$75.5M
|
+$71.8M
|
+4,162,041
|
New
|
|
|
13
|
Vestal Point Capital
New York
|
$72.5M
|
+$66.9M
|
+3,880,000
|
+3,233%
|
|
|
14
|
Geode Capital Management
Boston,
Massachusetts
|
$63.5M
|
+$4.15M
|
+240,685
|
+7%
|
|
|
15
|
Armistice Capital
New York
|
$57.6M
|
-$1.29M
|
-74,598
|
-2%
|
|
|
16
|
Frazier Life Sciences Management
Palo Alto,
California
|
$57.2M
|
–
|
–
|
–
|
|
|
17
|
|
$55.6M
|
-$5.11M
|
-296,436
|
-8%
|
|
|
18
|
|
$52.9M
|
+$12.3M
|
+715,700
|
+32%
|
|
|
19
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$42.2M
|
+$79K
|
+4,584
|
+0.2%
|
|
|
20
|
Siren LLC
Greenwich,
Connecticut
|
$40.4M
|
-$22M
|
-1,273,816
|
-36%
|
|
|
21
|
|
$39.4M
|
–
|
–
|
–
|
|
|
22
|
Franklin Resources
San Mateo,
California
|
$36.4M
|
+$42.1K
|
+2,444
|
+0.1%
|
|
|
23
|
Deep Track Capital
Greenwich,
Connecticut
|
$36.3M
|
-$11.2M
|
-650,000
|
-25%
|
|
|
24
|
|
$34.9M
|
+$7.41M
|
+429,468
|
+29%
|
|
|
25
|
|
$31.2M
|
-$9.66M
|
-560,075
|
-25%
|
|
