|
1
|
T. Rowe Price Investment Management
Baltimore,
Maryland
|
$687M
|
+$2.35M
|
+126,486
|
+0.4%
|
|
|
2
|
|
$276M
|
+$13.1M
|
+704,460
|
+6%
|
|
|
3
|
|
$267M
|
+$223M
|
+11,997,738
|
New
|
|
|
4
|
Fidelity Investments
Boston,
Massachusetts
|
$249M
|
+$42.7M
|
+2,298,020
|
+26%
|
|
|
5
|
State Street
Boston,
Massachusetts
|
$166M
|
+$15M
|
+804,517
|
+12%
|
|
|
6
|
Orbis Allan Gray
Hamilton,
Bermuda
|
$156M
|
+$4.54M
|
+244,311
|
+4%
|
|
|
7
|
Atlas Venture Life Science Advisors
Cambridge,
Massachusetts
|
$151M
|
-$43.3M
|
-2,330,366
|
-26%
|
|
|
8
|
Vanguard Capital Management
Malvern,
Pennsylvania
|
$140M
|
-$1.75M
|
-94,100
|
-1%
|
|
|
9
|
TCG Crossover Management
Palo Alto,
California
|
$103M
|
–
|
–
|
–
|
|
|
10
|
Vanguard Portfolio Management
Malvern,
Pennsylvania
|
$89.9M
|
-$2.11M
|
-113,613
|
-3%
|
|
|
11
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$87.4M
|
+$29.9M
|
+1,608,433
|
+69%
|
|
|
12
|
FCPM III Services
Naarden,
Netherlands
|
$85.5M
|
-$14.8M
|
-796,130
|
-17%
|
|
|
13
|
Geode Capital Management
Boston,
Massachusetts
|
$83.2M
|
+$4.45M
|
+239,313
|
+7%
|
|
|
14
|
Vestal Point Capital
New York
|
$75M
|
-$11.6M
|
-625,000
|
-16%
|
|
|
15
|
|
$71.9M
|
+$5.91M
|
+317,800
|
+11%
|
|
|
16
|
Frazier Life Sciences Management
Palo Alto,
California
|
$70M
|
–
|
–
|
–
|
|
|
17
|
Armistice Capital
New York
|
$68.6M
|
-$1.63M
|
-87,884
|
-3%
|
|
|
18
|
|
$67.2M
|
-$1.89M
|
-101,817
|
-3%
|
|
|
19
|
Perceptive Advisors
New York
|
$59.7M
|
-$36.8M
|
-1,979,604
|
-42%
|
|
|
20
|
Logos Global Management
San Francisco,
California
|
$56.6M
|
+$21.4M
|
+1,150,000
|
+82%
|
|
|
21
|
Bank of America
Charlotte,
North Carolina
|
$49.6M
|
+$14.7M
|
+790,085
|
+55%
|
|
|
22
|
|
$48.3M
|
–
|
–
|
–
|
|
|
23
|
|
$47.9M
|
+$8.07M
|
+434,079
|
+25%
|
|
|
24
|
Siren LLC
Greenwich,
Connecticut
|
$47.3M
|
-$1.86M
|
-100,000
|
-4%
|
|
|
25
|
Franklin Resources
San Mateo,
California
|
$45.1M
|
+$404K
|
+21,737
|
+1%
|
|
