|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$324M
|
+$148M
|
+3,707,734
|
+70%
|
|
|
2
|
Atlas Venture Life Science Advisors
Cambridge,
Massachusetts
|
$288M
|
–
|
–
|
–
|
|
|
3
|
|
$280M
|
+$16.2M
|
+407,126
|
+6%
|
|
|
4
|
Vanguard Group
Malvern,
Pennsylvania
|
$247M
|
+$85.4M
|
+2,146,083
|
+45%
|
|
|
5
|
|
$245M
|
+$17.2M
|
+431,503
|
+7%
|
|
|
6
|
Janus Henderson Group
London,
|
$245M
|
+$87.1M
|
+2,189,339
|
+47%
|
|
|
7
|
RA Capital Management
Boston,
Massachusetts
|
$229M
|
+$13.2M
|
+331,940
|
+5%
|
|
|
8
|
FCPM III Services
Naarden,
Netherlands
|
$214M
|
-$75.3M
|
-1,891,295
|
-24%
|
|
|
9
|
State Street
Boston,
Massachusetts
|
$131M
|
+$17.5M
|
+440,890
|
+14%
|
|
|
10
|
Deep Track Capital
Greenwich,
Connecticut
|
$118M
|
-$28.6M
|
-718,000
|
-18%
|
|
|
11
|
Citadel Advisors
Miami,
Florida
|
$106M
|
-$54.8M
|
-1,376,666
|
-32%
|
|
|
12
|
TCG Crossover Management
Palo Alto,
California
|
$95.2M
|
–
|
–
|
–
|
|
|
13
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$94.7M
|
+$10.8M
|
+270,224
|
+11%
|
|
|
14
|
Adage Capital Partners
Boston,
Massachusetts
|
$86.3M
|
-$36.8M
|
-925,028
|
-28%
|
|
|
15
|
|
$78.1M
|
–
|
–
|
–
|
|
|
16
|
Holocene Advisors
New York
|
$71.2M
|
-$3.73M
|
-93,712
|
-5%
|
|
|
17
|
Geode Capital Management
Boston,
Massachusetts
|
$66.8M
|
+$3.37M
|
+84,760
|
+5%
|
|
|
18
|
Jennison Associates
New York
|
$48.4M
|
+$785K
|
+19,730
|
+1%
|
|
|
19
|
First Light Asset Management
Edina,
Minnesota
|
$45.2M
|
+$34.8M
|
+874,852
|
+229%
|
|
|
20
|
Franklin Resources
San Mateo,
California
|
$44.7M
|
-$14.8M
|
-371,996
|
-22%
|
|
|
21
|
Federated Hermes
Pittsburgh,
Pennsylvania
|
$43.7M
|
+$81.9K
|
+2,058
|
+0.2%
|
|
|
22
|
Armistice Capital
New York
|
$41.5M
|
+$7.34M
|
+184,313
|
+19%
|
|
|
23
|
Siren LLC
Greenwich,
Connecticut
|
$40.8M
|
+$45.2M
|
+1,134,664
|
New
|
|
|
24
|
Vivo Capital
Palo Alto,
California
|
$40M
|
-$20.7M
|
-520,176
|
-32%
|
|
|
25
|
|
$37.8M
|
+$19.7M
|
+494,210
|
+88%
|
|
