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Denali Therapeutics
DNLI

Overview Fund Activity

221 hedge funds and large institutions have $1.81B invested in Denali Therapeutics in 2025 Q1 according to their latest regulatory filings, with 36 funds opening new positions, 73 increasing their positions, 80 reducing their positions, and 35 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
221
Holders Change
-2
Holders Change %
-0.9%
% of All Funds
3%
Holding in Top 10
1
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-50%
% of All Funds
0.01%
New
36
Increased
73
Reduced
80
Closed
35
Calls
$848K
Puts
$515K
Net Calls
+$333K
Net Calls Change
-$267K

Top Buyers

1
UBS AM
UBS AM
Illinois
+$43.3M
2
Wellington Management Group
Wellington Management Group
Massachusetts
+$21.2M
3
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
+$17.8M
4
Millennium Management
Millennium Management
New York
+$14.8M
5
Squarepoint
Squarepoint
New York
+$8.68M

Top Sellers

1
CCM
Camber Capital Management
Massachusetts
-$13.6M
2
Point72 Asset Management
Point72 Asset Management
Connecticut
-$11.2M
3
Capital Research Global Investors
Capital Research Global Investors
California
-$9.68M
4
Fidelity Investments
Fidelity Investments
Massachusetts
-$8.24M
5
PAMP
Polar Asset Management Partners
Ontario, Canada
-$7.21M
Name Holding Trade Value Shares
Change 		Shares
Change %
National Bank of Canada
201
National Bank of Canada
Quebec, Canada
$952 +$857 +63 +900%
SO
202
Sierra Ocean
California
$897 +$897 +66 New
RIL
203
Rothschild Investment LLC
Illinois
$884 -$476 -35 -35%
BIA
204
Bell Investment Advisors
California
$707 – – –
PWAM
205
Private Wealth Asset Management
Iowa
$517 +$517 +38 New
Optiver Holding
206
Optiver Holding
Netherlands
$421 +$421 +31 New
SC
207
Stephens Consulting
Michigan
$408 +$408 +30 New
SC
208
SouthState Corp
Florida
$408 +$408 +30 New
SPIA
209
Steward Partners Investment Advisory
New York
$340 – – –
FHA
210
First Horizon Advisors
Tennessee
$339 – – –
PS
211
Principal Securities
Iowa
$285 – – –
HCP
212
Hexagon Capital Partners
Arkansas
$204 +$41 +3 +25%
SW
213
SVB Wealth
Massachusetts
$150 +$150 +11 New
FFA
214
Farther Finance Advisors
California
$86 -$344 -28 -80%
SS
215
SBI Securities
Japan
$68 – – –
GFPC
216
Global Financial Private Client
Florida
$68 +$41 +3 +150%
SIC
217
SJS Investment Consulting
Ohio
$41 +$41 +3 New
DPW
218
DiNuzzo Private Wealth
Pennsylvania
$28 +$28 +2 New
BHWM
219
Bay Harbor Wealth Management
Maryland
$13 +$13 +1 New
Norges Bank
220
Norges Bank
Norway
– -$21.7M -1,065,608 Closed
Point72 Asset Management
221
Point72 Asset Management
Connecticut
– -$11.2M -548,739 Closed
Holocene Advisors
222
Holocene Advisors
New York
– -$4.06M -199,072 Closed
SFI
223
Susquehanna Fundamental Investments
Pennsylvania
– -$3.92M -192,563 Closed
CCM
224
Cinctive Capital Management
New York
– -$2.66M -130,445 Closed
FAM
225
Fred Alger Management
New York
– -$1.87M -91,807 Closed
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