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Denali Therapeutics

221 hedge funds and large institutions have $1.81B invested in Denali Therapeutics in 2025 Q1 according to their latest regulatory filings, with 35 funds opening new positions, 73 increasing their positions, 81 reducing their positions, and 35 closing their positions.

New
Increased
Maintained
Reduced
Closed

more call options, than puts

Call options by funds: $ | Put options by funds: $

more ownership

Funds ownership:

more first-time investments, than exits

New positions opened: | Existing positions closed:

less funds holding

Funds holding:

10% less repeat investments, than reductions

Existing positions increased: 73 | Existing positions reduced: 81

31% less capital invested

Capital invested by funds: $2.61B → $1.81B (-$800M)

50% less funds holding in top 10

Funds holding in top 10: 21 (-1)

Holders
221
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
1
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$848K
Puts
$515K
Net Calls
Net Calls Change

Top Buyers

1 +$43.3M
2 +$21.2M
3 +$17.8M
4
Millennium Management
Millennium Management
New York
+$14.8M
5
Squarepoint
Squarepoint
New York
+$8.68M
Name Holding Trade Value Shares
Change
Change in
Stake
151
$166K
152
$164K
153
$152K
154
$144K
155
$138K
156
$118K
157
$95K
158
$88K
159
$71.8K
160
$61K
161
$59K
162
$50.9K
163
$50.1K
164
$43.7K
165
$43.3K
166
$41K
167
$35.9K
168
$28.7K
169
$28K
170
$20.4K
171
$19.3K
172
$16.1K
173
$15.9K
174
$14.3K
175
$13.6K