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Denali Therapeutics
DNLI

Overview Fund Activity

230 hedge funds and large institutions have $1.93B invested in Denali Therapeutics in 2025 Q2 according to their latest regulatory filings, with 46 funds opening new positions, 83 increasing their positions, 64 reducing their positions, and 36 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
230
Holders Change
+9
Holders Change %
+4.07%
% of All Funds
3.08%
Holding in Top 10
1
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.01%
New
46
Increased
83
Reduced
64
Closed
36
Calls
$2.08M
Puts
$630K
Net Calls
+$1.45M
Net Calls Change
+$1.12M

Top Buyers

1
T. Rowe Price Investment Management
T. Rowe Price Investment Management
Maryland
+$45.4M
2
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
+$31M
3
Point72 Asset Management
Point72 Asset Management
Connecticut
+$31M
4
MCM
Masters Capital Management
Georgia
+$8.39M
5
Voloridge Investment Management
Voloridge Investment Management
Florida
+$6.56M

Top Sellers

1
Wellington Management Group
Wellington Management Group
Massachusetts
-$80.4M
2
BlackRock
BlackRock
New York
-$24.9M
3
CCM
Camber Capital Management
Massachusetts
-$11.9M
4
Marshall Wace
Marshall Wace
United Kingdom
-$11M
5
Squarepoint
Squarepoint
New York
-$9.34M
Name Holding Trade Value Shares
Change 		Shares
Change %
PFSRSONJ
126
Police & Firemen's Retirement System of New Jersey
New Jersey
$425K +$54.8K +3,915 +15%
CUAMC
127
China Universal Asset Management Company
China
$408K +$699 +50 +0.2%
DFCM
128
Dark Forest Capital Management
Puerto Rico
$398K -$733K -52,387 -65%
Two Sigma Advisers
129
Two Sigma Advisers
New York
$386K -$108K -7,700 -22%
EAM
130
Erste Asset Management
Austria
$379K – – –
PA
131
Profund Advisors
Maryland
$374K -$16K -1,146 -4%
Raymond James Financial
132
Raymond James Financial
Florida
$372K +$9.26K +662 +3%
KK
133
KLP Kapitalforvaltning
Norway
$365K – – –
CCM
134
Cinctive Capital Management
New York
$340K +$340K +24,310 New
A
135
AlphaQuest
New York
$321K -$29.3K -2,096 -8%
HighTower Advisors
136
HighTower Advisors
Illinois
$315K -$15K -1,070 -5%
Capital Fund Management (CFM)
137
Capital Fund Management (CFM)
France
$306K +$306K +21,871 New
Universal-Beteiligungs- und Servicegesellschaft
138
Universal-Beteiligungs- und Servicegesellschaft
Germany
$301K +$39K +2,785 +15%
AQR Capital Management
139
AQR Capital Management
Connecticut
$297K +$297K +21,217 New
Two Sigma Investments
140
Two Sigma Investments
New York
$270K -$1.16M -83,103 -81%
BNP Paribas Financial Markets
141
BNP Paribas Financial Markets
France
$267K +$145K +10,367 +119%
VF
142
Virtu Financial
New York
$258K +$258K +18,438 New
BCG
143
Breakwater Capital Group
New Jersey
$239K +$29.1K +2,081 +14%
Prudential Financial
144
Prudential Financial
New Jersey
$236K -$304K -21,765 -56%
CWM
145
CIBC World Markets
New York
$228K -$158K -11,264 -41%
PCM
146
Prelude Capital Management
New York
$223K +$223K +15,940 New
VPIM
147
Vanguard Personalized Indexing Management
California
$214K +$214K +15,329 New
NIM
148
NEOS Investment Management
Connecticut
$212K – – –
TE
149
Tema ETFs
New York
$212K – – –
EF
150
Empowered Funds
Pennsylvania
$207K -$81.4K -5,819 -28%
4 5
6
7 8