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Denali Therapeutics

222 hedge funds and large institutions have $1.85B invested in Denali Therapeutics in 2025 Q1 according to their latest regulatory filings, with 35 funds opening new positions, 74 increasing their positions, 81 reducing their positions, and 34 closing their positions.

New
Increased
Maintained
Reduced
Closed

more call options, than puts

Call options by funds: $ | Put options by funds: $

more ownership

Funds ownership:

more first-time investments, than exits

New positions opened: | Existing positions closed:

less funds holding

Funds holding:

9% less repeat investments, than reductions

Existing positions increased: 74 | Existing positions reduced: 81

29% less capital invested

Capital invested by funds: $2.61B → $1.85B (-$758M)

50% less funds holding in top 10

Funds holding in top 10: 21 (-1)

Holders
222
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
1
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$848K
Puts
$515K
Net Calls
Net Calls Change
Name Holding Trade Value Shares
Change
Change in
Stake
126
$375K
127
$360K
128
$355K
129
$353K
130
$341K
131
$324K
132
$321K
133
$285K
134
$281K
135
$272K
136
$254K
137
$235K
138
$234K
139
$226K
140
$206K
141
$206K
142
$204K
143
$196K
144
$194K
145
$189K
146
$187K
147
$183K
148
$183K
149
$178K
150
$171K