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Denali Therapeutics

221 hedge funds and large institutions have $1.81B invested in Denali Therapeutics in 2025 Q1 according to their latest regulatory filings, with 35 funds opening new positions, 73 increasing their positions, 81 reducing their positions, and 35 closing their positions.

New
Increased
Maintained
Reduced
Closed

more call options, than puts

Call options by funds: $ | Put options by funds: $

more ownership

Funds ownership:

more first-time investments, than exits

New positions opened: | Existing positions closed:

less funds holding

Funds holding:

10% less repeat investments, than reductions

Existing positions increased: 73 | Existing positions reduced: 81

31% less capital invested

Capital invested by funds: $2.61B → $1.81B (-$800M)

50% less funds holding in top 10

Funds holding in top 10: 21 (-1)

Holders
221
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
1
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$848K
Puts
$515K
Net Calls
Net Calls Change

Top Buyers

1 +$43.3M
2 +$21.2M
3 +$17.8M
4
Millennium Management
Millennium Management
New York
+$14.8M
5
Squarepoint
Squarepoint
New York
+$8.68M
Name Holding Trade Value Shares
Change
Change in
Stake
126
$360K
127
$355K
128
$353K
129
$341K
130
$324K
131
$321K
132
$285K
133
$281K
134
$272K
135
$254K
136
$235K
137
$234K
138
$226K
139
$206K
140
$206K
141
$204K
142
$196K
143
$194K
144
$189K
145
$187K
146
$183K
147
$183K
148
$178K
149
$171K
150
$169K