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Denali Therapeutics
DNLI

Overview Fund Activity

230 hedge funds and large institutions have $1.93B invested in Denali Therapeutics in 2025 Q2 according to their latest regulatory filings, with 46 funds opening new positions, 83 increasing their positions, 64 reducing their positions, and 36 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
230
Holders Change
+9
Holders Change %
+4.07%
% of All Funds
3.08%
Holding in Top 10
1
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.01%
New
46
Increased
83
Reduced
64
Closed
36
Calls
$2.08M
Puts
$630K
Net Calls
+$1.45M
Net Calls Change
+$1.12M

Top Buyers

1
T. Rowe Price Investment Management
T. Rowe Price Investment Management
Maryland
+$45.4M
2
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
+$31M
3
Point72 Asset Management
Point72 Asset Management
Connecticut
+$31M
4
MCM
Masters Capital Management
Georgia
+$8.39M
5
Voloridge Investment Management
Voloridge Investment Management
Florida
+$6.56M

Top Sellers

1
Wellington Management Group
Wellington Management Group
Massachusetts
-$80.4M
2
BlackRock
BlackRock
New York
-$24.9M
3
CCM
Camber Capital Management
Massachusetts
-$11.9M
4
Marshall Wace
Marshall Wace
United Kingdom
-$11M
5
Squarepoint
Squarepoint
New York
-$9.34M
Name Holding Trade Value Shares
Change 		Shares
Change %
DekaBank Deutsche Girozentrale
101
DekaBank Deutsche Girozentrale
Germany
$841K -$62K -4,410 -7%
Janus Henderson Group
102
Janus Henderson Group
United Kingdom
$839K – – –
Creative Planning
103
Creative Planning
Kansas
$807K +$379K +27,114 +89%
P8IP
104
Pier 88 Investment Partners
California
$800K +$171K +12,240 +27%
Tudor Investment Corp
105
Tudor Investment Corp
Connecticut
$776K -$240K -17,149 -24%
IIM
106
Ironwood Investment Management
Massachusetts
$744K +$54.7K +3,907 +8%
GC
107
Guggenheim Capital
Illinois
$726K -$58.1K -4,152 -7%
Verition Fund Management
108
Verition Fund Management
Connecticut
$711K +$519K +37,080 +270%
MCM
109
MAI Capital Management
Ohio
$651K – – –
Victory Capital Management
110
Victory Capital Management
Texas
$638K +$55.8K +3,989 +10%
Pathstone Holdings
111
Pathstone Holdings
New Jersey
$630K +$94.2K +6,735 +18%
ERSOT
112
Employees Retirement System of Texas
Texas
$612K – – –
Zurich Cantonal Bank
113
Zurich Cantonal Bank
Switzerland
$610K +$53.6K +3,830 +10%
Skandinaviska Enskilda Banken (SEB)
114
Skandinaviska Enskilda Banken (SEB)
Sweden
$605K – – –
KOCAA
115
Knights of Columbus Asset Advisors
Connecticut
$538K -$25.1K -1,796 -4%
New York State Common Retirement Fund
116
New York State Common Retirement Fund
New York
$538K -$444K -31,762 -45%
Handelsbanken Fonder
117
Handelsbanken Fonder
Sweden
$536K – – –
ASRS
118
Arizona State Retirement System
Arizona
$533K +$14K +1,002 +3%
VOYA Investment Management
119
VOYA Investment Management
Georgia
$502K -$211K -15,103 -30%
ACM
120
ADAR1 Capital Management
Texas
$500K +$306K +21,843 +157%
DIA
121
Dana Investment Advisors
Wisconsin
$497K +$47.7K +3,406 +11%
Teacher Retirement System of Texas
122
Teacher Retirement System of Texas
Texas
$493K +$5.09K +364 +1%
State Board of Administration of Florida Retirement System
123
State Board of Administration of Florida Retirement System
Florida
$478K – – –
Envestnet Asset Management
124
Envestnet Asset Management
Illinois
$469K +$29.5K +2,108 +7%
ProShare Advisors
125
ProShare Advisors
Maryland
$456K -$12.3K -879 -3%
3 4
5
6 7