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Denali Therapeutics
DNLI

Overview Fund Activity

221 hedge funds and large institutions have $1.81B invested in Denali Therapeutics in 2025 Q1 according to their latest regulatory filings, with 36 funds opening new positions, 73 increasing their positions, 80 reducing their positions, and 35 closing their positions.

Holders
221
Holders Change
-2
Holders Change %
-0.9%
% of All Funds
3%
Holding in Top 10
1
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-50%
% of All Funds
0.01%
New
36
Increased
73
Reduced
80
Closed
35
Calls
$848K
Puts
$515K
Net Calls
+$333K
Net Calls Change
-$267K

Top Buyers

1
UBS AM
1
UBS AM
Illinois
$92M
2
Wellington Management Group
2
Wellington Management Group
Massachusetts
$155M
3
T. Rowe Price Associates
3
T. Rowe Price Associates
Maryland
$59.4M
4
Millennium Management
4
Millennium Management
New York
$20.3M
5
Squarepoint
5
Squarepoint
New York
$9.34M

Top Sellers

1
Norges Bank
1
Norges Bank
Norway
$0
2
CCM
2
Camber Capital Management
Massachusetts
$17M
3
Point72 Asset Management
3
Point72 Asset Management
Connecticut
$0
4
Capital Research Global Investors
4
Capital Research Global Investors
California
$64.8M
5
Fidelity Investments
5
Fidelity Investments
Massachusetts
$101M
Name Market Value Shares Shares
Change 		Shares
Change %
MCM
101
MAI Capital Management
Ohio
$633K 46,526 – –
P8IP
102
Pier 88 Investment Partners
California
$611K 44,910 -500 -1%
Walleye Capital
103
Walleye Capital
New York
$600K 44,138 +19,318 +78%
ERSOT
104
Employees Retirement System of Texas
Texas
$595K 43,769 – –
Skandinaviska Enskilda Banken (SEB)
105
Skandinaviska Enskilda Banken (SEB)
Sweden
$588K 43,245 – –
GCM
106
Graham Capital Management
Connecticut
$585K 43,005 +22,299 +108%
Victory Capital Management
107
Victory Capital Management
Texas
$566K 41,627 +3,119 +8%
KOCAA
108
Knights of Columbus Asset Advisors
Connecticut
$548K 40,275 +1,058 +3%
Zurich Cantonal Bank
109
Zurich Cantonal Bank
Switzerland
$540K 39,757 – –
Prudential Financial
110
Prudential Financial
New Jersey
$525K 38,643 -71,950 -65%
Handelsbanken Fonder
111
Handelsbanken Fonder
Sweden
$521K 38,300 – –
Pathstone Holdings
112
Pathstone Holdings
New Jersey
$521K 38,305 +17,081 +80%
ASRS
113
Arizona State Retirement System
Arizona
$505K 37,112 -283 -0.8%
Two Sigma Advisers
114
Two Sigma Advisers
New York
$480K 35,300 +20,200 +134%
Teacher Retirement System of Texas
115
Teacher Retirement System of Texas
Texas
$474K 34,857 -3,321 -9%
State Board of Administration of Florida Retirement System
116
State Board of Administration of Florida Retirement System
Florida
$465K 34,168 – –
ProShare Advisors
117
ProShare Advisors
Maryland
$455K 33,461 -8,364 -20%
DIA
118
Dana Investment Advisors
Wisconsin
$437K 32,155 -2,147 -6%
Envestnet Asset Management
119
Envestnet Asset Management
Illinois
$427K 31,430 -6,192 -16%
Creative Planning
120
Creative Planning
Kansas
$416K 30,564 -17,386 -36%
EAM
121
Erste Asset Management
Austria
$398K 26,900 – –
CUAMC
122
China Universal Asset Management Company
China
$396K 29,128 -1,389 -5%
PA
123
Profund Advisors
Maryland
$379K 27,869 -866 -3%
VIM
124
VELA Investment Management
Ohio
$378K 27,771 +12,136 +78%
CWM
125
CIBC World Markets
New York
$375K 27,582 +15,949 +137%
3 4
5
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