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Denali Therapeutics

222 hedge funds and large institutions have $1.85B invested in Denali Therapeutics in 2025 Q1 according to their latest regulatory filings, with 35 funds opening new positions, 74 increasing their positions, 81 reducing their positions, and 34 closing their positions.

New
Increased
Maintained
Reduced
Closed

65% more call options, than puts

Call options by funds: $848K | Put options by funds: $515K

4.71% more ownership

Funds ownership: 88.89%93.6% (+4.7%)

3% more first-time investments, than exits

New positions opened: 35 | Existing positions closed: 34

0% less funds holding

Funds holding: 223222 (-1)

9% less repeat investments, than reductions

Existing positions increased: 74 | Existing positions reduced: 81

29% less capital invested

Capital invested by funds: $2.61B → $1.85B (-$758M)

50% less funds holding in top 10

Funds holding in top 10: 21 (-1)

Holders
222
Holders Change
-1
Holders Change %
-0.45%
% of All Funds
2.98%
Holding in Top 10
1
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-50%
% of All Funds
0.01%
New
35
Increased
74
Reduced
81
Closed
34
Calls
$848K
Puts
$515K
Net Calls
+$333K
Net Calls Change
-$267K
Name Holding Trade Value Shares
Change
Change in
Stake
SG Americas Securities
101
SG Americas Securities
New York
$658K +$716K +37,362 +340%
MCM
102
MAI Capital Management
Ohio
$633K
P8IP
103
Pier 88 Investment Partners
California
$611K -$9.58K -500 -1%
Walleye Capital
104
Walleye Capital
New York
$600K +$370K +19,318 +78%
ERSOT
105
Employees Retirement System of Texas
Texas
$595K
Skandinaviska Enskilda Banken (SEB)
106
Skandinaviska Enskilda Banken (SEB)
Sweden
$588K
GCM
107
Graham Capital Management
Connecticut
$585K +$427K +22,299 +108%
Victory Capital Management
108
Victory Capital Management
Texas
$566K +$59.8K +3,119 +8%
KOCAA
109
Knights of Columbus Asset Advisors
Connecticut
$548K +$20.3K +1,058 +3%
Zurich Cantonal Bank
110
Zurich Cantonal Bank
Switzerland
$540K
Prudential Financial
111
Prudential Financial
New Jersey
$525K -$1.38M -71,950 -65%
Handelsbanken Fonder
112
Handelsbanken Fonder
Sweden
$521K
Pathstone Holdings
113
Pathstone Holdings
New Jersey
$521K +$327K +17,081 +80%
ASRS
114
Arizona State Retirement System
Arizona
$505K -$5.42K -283 -0.8%
Two Sigma Advisers
115
Two Sigma Advisers
New York
$480K +$387K +20,200 +134%
Teacher Retirement System of Texas
116
Teacher Retirement System of Texas
Texas
$474K -$63.6K -3,321 -9%
State Board of Administration of Florida Retirement System
117
State Board of Administration of Florida Retirement System
Florida
$465K
ProShare Advisors
118
ProShare Advisors
Maryland
$455K -$160K -8,364 -20%
DIA
119
Dana Investment Advisors
Wisconsin
$437K -$41.1K -2,147 -6%
Envestnet Asset Management
120
Envestnet Asset Management
Illinois
$427K -$119K -6,192 -16%
Creative Planning
121
Creative Planning
Kansas
$416K -$333K -17,386 -36%
EAM
122
Erste Asset Management
Austria
$398K
CUAMC
123
China Universal Asset Management Company
China
$396K -$26.6K -1,389 -5%
PA
124
Profund Advisors
Maryland
$379K -$16.6K -866 -3%
VIM
125
VELA Investment Management
Ohio
$378K +$233K +12,136 +78%