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Denali Therapeutics
DNLI

Overview Fund Activity

230 hedge funds and large institutions have $1.93B invested in Denali Therapeutics in 2025 Q2 according to their latest regulatory filings, with 46 funds opening new positions, 83 increasing their positions, 64 reducing their positions, and 36 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
230
Holders Change
+9
Holders Change %
+4.07%
% of All Funds
3.08%
Holding in Top 10
1
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.01%
New
46
Increased
83
Reduced
64
Closed
36
Calls
$2.08M
Puts
$630K
Net Calls
+$1.45M
Net Calls Change
+$1.12M

Top Buyers

1
T. Rowe Price Investment Management
T. Rowe Price Investment Management
Maryland
+$45.4M
2
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
+$31M
3
Point72 Asset Management
Point72 Asset Management
Connecticut
+$31M
4
MCM
Masters Capital Management
Georgia
+$8.39M
5
Voloridge Investment Management
Voloridge Investment Management
Florida
+$6.56M

Top Sellers

1
Wellington Management Group
Wellington Management Group
Massachusetts
-$80.4M
2
BlackRock
BlackRock
New York
-$24.9M
3
CCM
Camber Capital Management
Massachusetts
-$11.9M
4
Marshall Wace
Marshall Wace
United Kingdom
-$11M
5
Squarepoint
Squarepoint
New York
-$9.34M
Name Holding Trade Value Shares
Change 		Shares
Change %
Mirae Asset Global ETFs Holdings
76
Mirae Asset Global ETFs Holdings
Hong Kong
$1.89M +$647K +46,196 +52%
Legal & General Group
77
Legal & General Group
United Kingdom
$1.84M -$283K -20,207 -13%
Rafferty Asset Management
78
Rafferty Asset Management
New York
$1.71M -$96.2K -6,873 -5%
California State Teachers Retirement System (CalSTRS)
79
California State Teachers Retirement System (CalSTRS)
California
$1.67M +$25.1K +1,792 +2%
EGM
80
Engineers Gate Manager
New York
$1.62M +$1.38M +98,903 +575%
WP
81
Woodline Partners
California
$1.59M – – –
TI
82
Trexquant Investment
Connecticut
$1.53M -$55.7K -3,982 -4%
Ameriprise
83
Ameriprise
Minnesota
$1.43M +$1.43M +102,033 New
RPAM
84
Rhenman & Partners Asset Management
Sweden
$1.4M – – –
SAI
85
Savvy Advisors Inc
New York
$1.37M +$1.37M +97,793 New
IWC
86
Integrated Wealth Concepts
Massachusetts
$1.34M +$1.34M +96,046 New
PAMP
87
Polar Asset Management Partners
Ontario, Canada
$1.28M +$988K +70,648 +337%
Wells Fargo
88
Wells Fargo
California
$1.25M +$173K +12,357 +16%
AG
89
Algert Global
California
$1.2M +$1.2M +85,840 New
Jane Street
90
Jane Street
New York
$1.19M -$1.8M -128,341 -60%
State of Wisconsin Investment Board
91
State of Wisconsin Investment Board
Wisconsin
$1.11M -$3.69K -264 -0.3%
MIM
92
MetLife Investment Management
New Jersey
$1.11M +$60.3K +4,310 +6%
AA
93
ALPS Advisors
Colorado
$1.1M -$462K -33,019 -30%
Citigroup
94
Citigroup
New York
$1.07M -$1.65M -117,689 -61%
IIM
95
INTECH Investment Management
Florida
$1.01M -$80.1K -5,724 -7%
Man Group
96
Man Group
United Kingdom
$980K -$1.39M -99,357 -59%
Thrivent Financial for Lutherans
97
Thrivent Financial for Lutherans
Minnesota
$950K – – –
TIAM
98
TT International Asset Management
United Kingdom
$909K +$909K +65,000 New
GCM
99
Graham Capital Management
Connecticut
$907K +$305K +21,794 +51%
Franklin Resources
100
Franklin Resources
California
$903K -$262K -18,723 -22%
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4
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