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Denali Therapeutics

221 hedge funds and large institutions have $1.81B invested in Denali Therapeutics in 2025 Q1 according to their latest regulatory filings, with 35 funds opening new positions, 73 increasing their positions, 81 reducing their positions, and 35 closing their positions.

New
Increased
Maintained
Reduced
Closed

more call options, than puts

Call options by funds: $ | Put options by funds: $

more ownership

Funds ownership:

more first-time investments, than exits

New positions opened: | Existing positions closed:

less funds holding

Funds holding:

10% less repeat investments, than reductions

Existing positions increased: 73 | Existing positions reduced: 81

31% less capital invested

Capital invested by funds: $2.61B → $1.81B (-$800M)

50% less funds holding in top 10

Funds holding in top 10: 21 (-1)

Holders
221
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
1
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$848K
Puts
$515K
Net Calls
Net Calls Change

Top Buyers

1 +$43.3M
2 +$21.2M
3 +$17.8M
4
Millennium Management
Millennium Management
New York
+$14.8M
5
Squarepoint
Squarepoint
New York
+$8.68M
Name Holding Trade Value Shares
Change
Change in
Stake
76
$1.39M
77
$1.36M
78
$1.27M
79
$1.21M
80
$1.13M
81
$1.1M
82
$1.09M
83
$1.06M
84
$1.05M
85
$1.05M
86
$1.02M
87
$987K
88
$979K
89
$955K
90
$935K
91
$927K
92
$924K
93
$888K
94
$828K
95
$779K
96
$762K
97
$745K
98
$693K
99
$670K
100
$658K