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Denali Therapeutics

222 hedge funds and large institutions have $1.85B invested in Denali Therapeutics in 2025 Q1 according to their latest regulatory filings, with 35 funds opening new positions, 74 increasing their positions, 81 reducing their positions, and 34 closing their positions.

New
Increased
Maintained
Reduced
Closed

65% more call options, than puts

Call options by funds: $848K | Put options by funds: $515K

4.71% more ownership

Funds ownership: 88.89%93.6% (+4.7%)

3% more first-time investments, than exits

New positions opened: 35 | Existing positions closed: 34

0% less funds holding

Funds holding: 223222 (-1)

9% less repeat investments, than reductions

Existing positions increased: 74 | Existing positions reduced: 81

29% less capital invested

Capital invested by funds: $2.61B → $1.85B (-$758M)

50% less funds holding in top 10

Funds holding in top 10: 21 (-1)

Holders
222
Holders Change
-1
Holders Change %
-0.45%
% of All Funds
2.98%
Holding in Top 10
1
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-50%
% of All Funds
0.01%
New
35
Increased
74
Reduced
81
Closed
34
Calls
$848K
Puts
$515K
Net Calls
+$333K
Net Calls Change
-$267K
Name Holding Trade Value Shares
Change
Change in
Stake
AA
76
ALPS Advisors
Colorado
$1.51M -$95.8K -5,002 -4%
Two Sigma Investments
77
Two Sigma Investments
New York
$1.39M -$1.48M -77,481 -43%
RPAM
78
Rhenman & Partners Asset Management
Sweden
$1.36M +$1.92M +100,000 New
State of New Jersey Common Pension Fund D
79
State of New Jersey Common Pension Fund D
New Jersey
$1.27M +$141K +7,347 +9%
Mirae Asset Global ETFs Holdings
80
Mirae Asset Global ETFs Holdings
Hong Kong
$1.21M +$65.8K +3,432 +4%
Franklin Resources
81
Franklin Resources
California
$1.13M +$161K +8,386 +11%
DFCM
82
Dark Forest Capital Management
Puerto Rico
$1.1M +$1.3M +67,932 +527%
State of Wisconsin Investment Board
83
State of Wisconsin Investment Board
Wisconsin
$1.09M -$253K -13,203 -14%
D.E. Shaw & Co
84
D.E. Shaw & Co
New York
$1.06M +$1.5M +78,218 New
IIM
85
INTECH Investment Management
Florida
$1.05M +$578K +30,189 +64%
Wells Fargo
86
Wells Fargo
California
$1.05M -$223K -11,651 -13%
MIM
87
MetLife Investment Management
New Jersey
$1.02M -$24.6K -1,285 -2%
Tudor Investment Corp
88
Tudor Investment Corp
Connecticut
$987K +$1.39M +72,597 New
TC
89
TwinBeech Capital
New York
$979K -$3.5M -182,564 -72%
New York State Common Retirement Fund
90
New York State Common Retirement Fund
New York
$955K -$1.43M -74,484 -51%
DekaBank Deutsche Girozentrale
91
DekaBank Deutsche Girozentrale
Germany
$935K +$84.5K +4,410 +7%
CCIA
92
Campbell & Co Investment Adviser
Maryland
$927K +$584K +30,500 +81%
Thrivent Financial for Lutherans
93
Thrivent Financial for Lutherans
Minnesota
$924K -$480K -25,055 -27%
Janus Henderson Group
94
Janus Henderson Group
United Kingdom
$888K
CF
95
Corebridge Financial
Texas
$828K -$17.3K -902 -1%
HSBC Holdings
96
HSBC Holdings
United Kingdom
$779K +$472K +24,613 +74%
GC
97
Guggenheim Capital
Illinois
$762K +$151K +7,881 +16%
YIH
98
Y-Intercept (HK)
Hong Kong
$745K +$360K +18,807 +52%
VOYA Investment Management
99
VOYA Investment Management
Georgia
$693K -$72.8K -3,802 -7%
IIM
100
Ironwood Investment Management
Massachusetts
$670K +$244K +12,759 +35%