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Denali Therapeutics
DNLI

Overview Fund Activity

221 hedge funds and large institutions have $1.81B invested in Denali Therapeutics in 2025 Q1 according to their latest regulatory filings, with 36 funds opening new positions, 73 increasing their positions, 80 reducing their positions, and 35 closing their positions.

Holders
221
Holders Change
-2
Holders Change %
-0.9%
% of All Funds
3%
Holding in Top 10
1
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-50%
% of All Funds
0.01%
New
36
Increased
73
Reduced
80
Closed
35
Calls
$848K
Puts
$515K
Net Calls
+$333K
Net Calls Change
-$267K

Top Buyers

1
UBS AM
1
UBS AM
Illinois
$92M
2
Wellington Management Group
2
Wellington Management Group
Massachusetts
$155M
3
T. Rowe Price Associates
3
T. Rowe Price Associates
Maryland
$59.4M
4
Millennium Management
4
Millennium Management
New York
$20.3M
5
Squarepoint
5
Squarepoint
New York
$9.34M

Top Sellers

1
Norges Bank
1
Norges Bank
Norway
$0
2
CCM
2
Camber Capital Management
Massachusetts
$17M
3
Point72 Asset Management
3
Point72 Asset Management
Connecticut
$0
4
Capital Research Global Investors
4
Capital Research Global Investors
California
$64.8M
5
Fidelity Investments
5
Fidelity Investments
Massachusetts
$101M
Name Market Value Shares Shares
Change 		Shares
Change %
Two Sigma Investments
76
Two Sigma Investments
New York
$1.39M 102,403 -77,481 -43%
RPAM
77
Rhenman & Partners Asset Management
Sweden
$1.36M 100,000 +100,000 New
State of New Jersey Common Pension Fund D
78
State of New Jersey Common Pension Fund D
New Jersey
$1.27M 93,590 +7,347 +9%
Mirae Asset Global ETFs Holdings
79
Mirae Asset Global ETFs Holdings
Hong Kong
$1.21M 88,507 +3,432 +4%
Franklin Resources
80
Franklin Resources
California
$1.13M 83,248 +8,386 +11%
DFCM
81
Dark Forest Capital Management
Puerto Rico
$1.1M 80,820 +67,932 +527%
State of Wisconsin Investment Board
82
State of Wisconsin Investment Board
Wisconsin
$1.09M 79,891 -13,203 -14%
D.E. Shaw & Co
83
D.E. Shaw & Co
New York
$1.06M 78,218 +78,218 New
IIM
84
INTECH Investment Management
Florida
$1.05M 77,590 +30,189 +64%
Wells Fargo
85
Wells Fargo
California
$1.05M 77,282 -11,651 -13%
MIM
86
MetLife Investment Management
New Jersey
$1.02M 74,765 -1,285 -2%
Tudor Investment Corp
87
Tudor Investment Corp
Connecticut
$987K 72,597 +72,597 New
TC
88
TwinBeech Capital
New York
$979K 72,022 -182,564 -72%
New York State Common Retirement Fund
89
New York State Common Retirement Fund
New York
$955K 70,240 -74,484 -51%
DekaBank Deutsche Girozentrale
90
DekaBank Deutsche Girozentrale
Germany
$935K 64,210 +4,410 +7%
CCIA
91
Campbell & Co Investment Adviser
Maryland
$927K 68,185 +30,500 +81%
Thrivent Financial for Lutherans
92
Thrivent Financial for Lutherans
Minnesota
$924K 67,917 -25,055 -27%
Janus Henderson Group
93
Janus Henderson Group
United Kingdom
$888K 60,028 – –
CF
94
Corebridge Financial
Texas
$828K 60,898 -902 -1%
HSBC Holdings
95
HSBC Holdings
United Kingdom
$779K 58,003 +24,613 +74%
GC
96
Guggenheim Capital
Illinois
$762K 56,012 +7,881 +16%
YIH
97
Y-Intercept (HK)
Hong Kong
$745K 54,813 +18,807 +52%
VOYA Investment Management
98
VOYA Investment Management
Georgia
$693K 51,011 -3,802 -7%
IIM
99
Ironwood Investment Management
Massachusetts
$670K 49,305 +12,759 +35%
SG Americas Securities
100
SG Americas Securities
New York
$658K 48,365 +37,362 +340%
2 3
4
5 6