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Denali Therapeutics
DNLI

Overview Fund Activity

227 hedge funds and large institutions have $1.92B invested in Denali Therapeutics in 2025 Q2 according to their latest regulatory filings, with 45 funds opening new positions, 82 increasing their positions, 63 reducing their positions, and 36 closing their positions.

Holders
227
Holders Change
+6
Holders Change %
+2.71%
% of All Funds
3.05%
Holding in Top 10
1
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.01%
New
45
Increased
82
Reduced
63
Closed
36
Calls
$1.54M
Puts
$630K
Net Calls
+$911K
Net Calls Change
+$578K

Top Buyers

1
Norges Bank
1
Norges Bank
Norway
$55.2M
2
T. Rowe Price Investment Management
2
T. Rowe Price Investment Management
Maryland
$45.4M
3
T. Rowe Price Associates
3
T. Rowe Price Associates
Maryland
$92.1M
4
Point72 Asset Management
4
Point72 Asset Management
Connecticut
$31M
5
MCM
5
Masters Capital Management
Georgia
$8.39M

Top Sellers

1
Wellington Management Group
1
Wellington Management Group
Massachusetts
$79.2M
2
BlackRock
2
BlackRock
New York
$169M
3
CCM
3
Camber Capital Management
Massachusetts
$5.6M
4
Marshall Wace
4
Marshall Wace
United Kingdom
$19.7M
5
Squarepoint
5
Squarepoint
New York
$0
Name Market Value Shares Shares
Change 		Shares
Change %
Rafferty Asset Management
76
Rafferty Asset Management
New York
$1.71M 122,262 -6,873 -5%
California State Teachers Retirement System (CalSTRS)
77
California State Teachers Retirement System (CalSTRS)
California
$1.67M 119,327 +1,792 +2%
EGM
78
Engineers Gate Manager
New York
$1.62M 116,101 +98,903 +575%
WP
79
Woodline Partners
California
$1.59M 113,517 – –
TI
80
Trexquant Investment
Connecticut
$1.53M 109,242 -3,982 -4%
Ameriprise
81
Ameriprise
Minnesota
$1.43M 102,033 +102,033 New
RPAM
82
Rhenman & Partners Asset Management
Sweden
$1.4M 100,000 – –
SAI
83
Savvy Advisors Inc
New York
$1.37M 97,793 +97,793 New
IWC
84
Integrated Wealth Concepts
Massachusetts
$1.34M 96,046 +96,046 New
PAMP
85
Polar Asset Management Partners
Ontario, Canada
$1.28M 91,600 +70,648 +337%
Wells Fargo
86
Wells Fargo
California
$1.25M 89,639 +12,357 +16%
AG
87
Algert Global
California
$1.2M 85,840 +85,840 New
Jane Street
88
Jane Street
New York
$1.19M 85,332 -128,341 -60%
State of Wisconsin Investment Board
89
State of Wisconsin Investment Board
Wisconsin
$1.11M 79,627 -264 -0.3%
MIM
90
MetLife Investment Management
New Jersey
$1.11M 79,075 +4,310 +6%
AA
91
ALPS Advisors
Colorado
$1.1M 78,356 -33,019 -30%
Citigroup
92
Citigroup
New York
$1.07M 76,315 -117,689 -61%
IIM
93
INTECH Investment Management
Florida
$1.01M 71,866 -5,724 -7%
Man Group
94
Man Group
United Kingdom
$980K 70,028 -99,357 -59%
Thrivent Financial for Lutherans
95
Thrivent Financial for Lutherans
Minnesota
$950K 67,917 – –
TIAM
96
TT International Asset Management
United Kingdom
$909K 65,000 +65,000 New
GCM
97
Graham Capital Management
Connecticut
$907K 64,799 +21,794 +51%
Franklin Resources
98
Franklin Resources
California
$903K 64,525 -18,723 -22%
DekaBank Deutsche Girozentrale
99
DekaBank Deutsche Girozentrale
Germany
$841K 59,800 -4,410 -7%
Janus Henderson Group
100
Janus Henderson Group
United Kingdom
$839K 60,028 – –
2 3
4
5 6