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Denali Therapeutics
DNLI

Overview Fund Activity

221 hedge funds and large institutions have $1.81B invested in Denali Therapeutics in 2025 Q1 according to their latest regulatory filings, with 36 funds opening new positions, 73 increasing their positions, 80 reducing their positions, and 35 closing their positions.

Holders
221
Holders Change
-2
Holders Change %
-0.9%
% of All Funds
3%
Holding in Top 10
1
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-50%
% of All Funds
0.01%
New
36
Increased
73
Reduced
80
Closed
35
Calls
$848K
Puts
$515K
Net Calls
+$333K
Net Calls Change
-$267K

Top Buyers

1
UBS AM
1
UBS AM
Illinois
$92M
2
Wellington Management Group
2
Wellington Management Group
Massachusetts
$155M
3
T. Rowe Price Associates
3
T. Rowe Price Associates
Maryland
$59.4M
4
Millennium Management
4
Millennium Management
New York
$20.3M
5
Squarepoint
5
Squarepoint
New York
$9.34M

Top Sellers

1
Norges Bank
1
Norges Bank
Norway
$0
2
CCM
2
Camber Capital Management
Massachusetts
$17M
3
Point72 Asset Management
3
Point72 Asset Management
Connecticut
$0
4
Capital Research Global Investors
4
Capital Research Global Investors
California
$64.8M
5
Fidelity Investments
5
Fidelity Investments
Massachusetts
$101M
Name Market Value Shares Shares
Change 		Shares
Change %
Swiss National Bank
51
Swiss National Bank
Switzerland
$3.41M 250,900 -2,600 -1%
BCM
52
Boxer Capital Management
California
$3.4M 250,000 +250,000 New
Hudson Bay Capital Management
53
Hudson Bay Capital Management
Connecticut
$3.4M 250,000 +157,500 +170%
Barclays
54
Barclays
United Kingdom
$3.27M 240,648 -37,419 -13%
Jane Street
55
Jane Street
New York
$2.9M 213,673 -15,492 -7%
EDRH
56
Edmond de Rothschild Holding
Switzerland
$2.8M 205,680 – –
SCM
57
SCS Capital Management
Massachusetts
$2.69M 197,998 +197,998 New
Citigroup
58
Citigroup
New York
$2.64M 194,004 +27,298 +16%
RhumbLine Advisers
59
RhumbLine Advisers
Massachusetts
$2.59M 190,256 -134 -0.1%
Invesco
60
Invesco
Georgia
$2.58M 189,427 +67,949 +56%
JPMorgan Chase & Co
61
JPMorgan Chase & Co
New York
$2.56M 188,403 -34,580 -16%
TRSOTSOK
62
Teachers Retirement System of the State of Kentucky
Kentucky
$2.49M 183,392 -23,732 -11%
Renaissance Technologies
63
Renaissance Technologies
New York
$2.35M 173,100 +173,100 New
Man Group
64
Man Group
United Kingdom
$2.3M 169,385 +146,950 +655%
Susquehanna International Group
65
Susquehanna International Group
Pennsylvania
$2.27M 167,197 +95,957 +135%
GAM
66
Groupama Asset Management
France
$2.14M 144,488 +34,281 +31%
Deutsche Bank
67
Deutsche Bank
Germany
$2.13M 156,252 -121,601 -44%
Legal & General Group
68
Legal & General Group
United Kingdom
$2.07M 151,962 +2,449 +2%
SCM
69
Soleus Capital Management
Connecticut
$1.84M 135,000 +135,000 New
Rafferty Asset Management
70
Rafferty Asset Management
New York
$1.76M 129,135 -12,175 -9%
DCM
71
DAFNA Capital Management
California
$1.74M 127,900 +127,900 New
California State Teachers Retirement System (CalSTRS)
72
California State Teachers Retirement System (CalSTRS)
California
$1.6M 117,535 -2,639 -2%
WP
73
Woodline Partners
California
$1.54M 113,517 +13,517 +14%
TI
74
Trexquant Investment
Connecticut
$1.54M 113,224 +52,568 +87%
AA
75
ALPS Advisors
Colorado
$1.51M 111,375 -5,002 -4%
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