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Denali Therapeutics
DNLI

Overview Fund Activity

230 hedge funds and large institutions have $1.93B invested in Denali Therapeutics in 2025 Q2 according to their latest regulatory filings, with 46 funds opening new positions, 83 increasing their positions, 64 reducing their positions, and 36 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
230
Holders Change
+9
Holders Change %
+4.07%
% of All Funds
3.08%
Holding in Top 10
1
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.01%
New
46
Increased
83
Reduced
64
Closed
36
Calls
$2.08M
Puts
$630K
Net Calls
+$1.45M
Net Calls Change
+$1.12M

Top Buyers

1
T. Rowe Price Investment Management
T. Rowe Price Investment Management
Maryland
+$45.4M
2
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
+$31M
3
Point72 Asset Management
Point72 Asset Management
Connecticut
+$31M
4
MCM
Masters Capital Management
Georgia
+$8.39M
5
Voloridge Investment Management
Voloridge Investment Management
Florida
+$6.56M

Top Sellers

1
Wellington Management Group
Wellington Management Group
Massachusetts
-$80.4M
2
BlackRock
BlackRock
New York
-$24.9M
3
CCM
Camber Capital Management
Massachusetts
-$11.9M
4
Marshall Wace
Marshall Wace
United Kingdom
-$11M
5
Squarepoint
Squarepoint
New York
-$9.34M
Name Holding Trade Value Shares
Change 		Shares
Change %
Charles Schwab
26
Charles Schwab
California
$14.8M +$645K +46,123 +5%
UBS Group
27
UBS Group
Switzerland
$13.3M +$2.27M +162,335 +21%
Aberdeen Group
28
Aberdeen Group
United Kingdom
$12.6M +$2M +142,936 +19%
Millennium Management
29
Millennium Management
New York
$12.6M -$8.29M -592,567 -40%
CC
30
Casdin Capital
New York
$12.5M -$1.4M -100,000 -10%
CS
31
Candriam SCA
Luxembourg
$11.8M -$195K -13,913 -2%
SL
32
Siren LLC
Connecticut
$11.5M – – –
Bank of New York Mellon
33
Bank of New York Mellon
New York
$11.1M -$4.38M -313,136 -28%
Voloridge Investment Management
34
Voloridge Investment Management
Florida
$10.8M +$6.56M +468,554 +155%
SC
35
Stempoint Capital
New York
$9.9M +$571K +40,837 +6%
Bank of America
36
Bank of America
North Carolina
$9.1M +$2.83M +202,465 +45%
CM
37
Cercano Management
Washington
$8.74M – – –
MCM
38
Masters Capital Management
Georgia
$8.39M +$8.39M +600,000 New
NL
39
Nuveen LLC
North Carolina
$8.33M +$3.81M +272,272 +84%
SBH
40
Segall Bryant & Hamill
Illinois
$7M +$3.07M +219,420 +78%
TD Asset Management
41
TD Asset Management
Ontario, Canada
$6.94M +$2.63M +187,710 +61%
Ensign Peak Advisors
42
Ensign Peak Advisors
Utah
$6.63M -$1.6M -114,090 -19%
YCM
43
Yiheng Capital Management
California
$6.58M – – –
Barclays
44
Barclays
United Kingdom
$5.96M +$2.59M +185,333 +77%
Pictet Asset Management
45
Pictet Asset Management
Switzerland
$5.85M +$1M +71,153 +21%
Holocene Advisors
46
Holocene Advisors
New York
$5.64M +$5.64M +403,172 New
CCM
47
Camber Capital Management
Massachusetts
$5.6M -$11.9M -850,000 -68%
CSS
48
Cubist Systematic Strategies
Connecticut
$5.55M +$5.55M +396,586 New
Royal Bank of Canada
49
Royal Bank of Canada
Ontario, Canada
$5.46M +$5.26M +375,719 +2,603%
Schroder Investment Management Group
50
Schroder Investment Management Group
United Kingdom
$5.41M +$1.33M +94,744 +32%
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