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Denali Therapeutics
DNLI

Overview Fund Activity

221 hedge funds and large institutions have $1.81B invested in Denali Therapeutics in 2025 Q1 according to their latest regulatory filings, with 36 funds opening new positions, 73 increasing their positions, 80 reducing their positions, and 35 closing their positions.

Holders
221
Holders Change
-2
Holders Change %
-0.9%
% of All Funds
3%
Holding in Top 10
1
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-50%
% of All Funds
0.01%
New
36
Increased
73
Reduced
80
Closed
35
Calls
$848K
Puts
$515K
Net Calls
+$333K
Net Calls Change
-$267K

Top Buyers

1
UBS AM
1
UBS AM
Illinois
$92M
2
Wellington Management Group
2
Wellington Management Group
Massachusetts
$155M
3
T. Rowe Price Associates
3
T. Rowe Price Associates
Maryland
$59.4M
4
Millennium Management
4
Millennium Management
New York
$20.3M
5
Squarepoint
5
Squarepoint
New York
$9.34M

Top Sellers

1
Norges Bank
1
Norges Bank
Norway
$0
2
CCM
2
Camber Capital Management
Massachusetts
$17M
3
Point72 Asset Management
3
Point72 Asset Management
Connecticut
$0
4
Capital Research Global Investors
4
Capital Research Global Investors
California
$64.8M
5
Fidelity Investments
5
Fidelity Investments
Massachusetts
$101M
Name Market Value Shares Shares
Change 		Shares
Change %
Charles Schwab
26
Charles Schwab
California
$13.7M 1,009,896 -18,566 -2%
CC
27
Casdin Capital
New York
$13.5M 990,000 – –
CS
28
Candriam SCA
Luxembourg
$11.7M 858,162 +25,185 +3%
SL
29
Siren LLC
Connecticut
$11.2M 821,513 -12,515 -2%
UBS Group
30
UBS Group
Switzerland
$10.7M 788,429 -64,432 -8%
Aberdeen Group
31
Aberdeen Group
United Kingdom
$10.3M 759,815 +357,533 +89%
Squarepoint
32
Squarepoint
New York
$9.34M 687,151 +638,532 +1,313%
SC
33
Stempoint Capital
New York
$9.07M 667,078 +82,750 +14%
CM
34
Cercano Management
Washington
$8.5M 625,000 – –
Artisan Partners
35
Artisan Partners
Wisconsin
$8.33M 612,438 -442,085 -42%
Ensign Peak Advisors
36
Ensign Peak Advisors
Utah
$7.99M 587,785 +241,481 +70%
YCM
37
Yiheng Capital Management
California
$6.39M 469,981 -230,117 -33%
Bank of America
38
Bank of America
North Carolina
$6.09M 447,757 +177,424 +66%
Pictet Asset Management
39
Pictet Asset Management
Switzerland
$5.06M 343,959 +324,603 +1,677%
CGL
40
Clarius Group LLC
Washington
$5.02M 368,995 -41,000 -10%
American Century Companies
41
American Century Companies
Missouri
$4.75M 349,420 -131,109 -27%
PC
42
Pier Capital
Connecticut
$4.56M 335,504 +3,185 +1%
NL
43
Nuveen LLC
North Carolina
$4.39M 322,945 +322,945 New
Schroder Investment Management Group
44
Schroder Investment Management Group
United Kingdom
$4.31M 291,795 +43,995 +18%
TD Asset Management
45
TD Asset Management
Ontario, Canada
$4.2M 308,580 +42,828 +16%
Voloridge Investment Management
46
Voloridge Investment Management
Florida
$4.11M 301,973 +301,973 New
Axa
47
Axa
France
$3.99M 293,381 -374 -0.1%
Qube Research & Technologies (QRT)
48
Qube Research & Technologies (QRT)
United Kingdom
$3.92M 288,221 -23,286 -7%
SBH
49
Segall Bryant & Hamill
Illinois
$3.82M 281,139 -7,936 -3%
Manulife (Manufacturers Life Insurance)
50
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$3.51M 258,132 +49,611 +24%
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