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Denali Therapeutics

190 hedge funds and large institutions have $2.8B invested in Denali Therapeutics in 2022 Q1 according to their latest regulatory filings, with 19 funds opening new positions, 68 increasing their positions, 69 reducing their positions, and 40 closing their positions.

New
Increased
Maintained
Reduced
Closed

0.82% more ownership

Funds ownership: 69.82%70.64% (+0.82%)

0% more funds holding in top 10

Funds holding in top 10: 22 (0)

1% less repeat investments, than reductions

Existing positions increased: 68 | Existing positions reduced: 69

11% less funds holding

Funds holding: 213190 (-23)

26% less capital invested

Capital invested by funds: $3.8B → $2.8B (-$998M)

53% less first-time investments, than exits

New positions opened: 19 | Existing positions closed: 40

55% less call options, than puts

Call options by funds: $818K | Put options by funds: $1.8M

Holders
190
Holders Change
-23
Holders Change %
-10.8%
% of All Funds
3%
Holding in Top 10
2
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.03%
New
19
Increased
68
Reduced
69
Closed
40
Calls
$818K
Puts
$1.8M
Net Calls
-$986K
Net Calls Change
+$7.7M
Name Holding Trade Value Shares
Change
Change in
Stake
American Century Companies
26
American Century Companies
Missouri
$17.3M +$6.5K +189 +0%
Artisan Partners
27
Artisan Partners
Wisconsin
$16.9M +$93.7K +2,723 +0.5%
UBS AM
28
UBS AM
Illinois
$14M -$179K -5,209 -1%
Goldman Sachs
29
Goldman Sachs
New York
$13.1M -$156K -4,536 -1%
N
30
Nuveen
North Carolina
$12.3M -$235K -6,815 -2%
Mitsubishi UFJ Trust & Banking
31
Mitsubishi UFJ Trust & Banking
Japan
$10.1M +$201K +5,850 +2%
Principal Financial Group
32
Principal Financial Group
Iowa
$8.65M -$2.11M -61,271 -19%
WP
33
Woodline Partners
California
$8.26M +$7.03M +204,224 +389%
IBT
34
International Biotechnology Trust
United Kingdom
$8.19M +$413K +12,000 +46%
Bank of America
35
Bank of America
North Carolina
$7.76M +$3.86M +112,287 +87%
WA
36
Wasatch Advisors
Utah
$7.64M +$2.17M +63,181 +36%
N
37
Natixis
France
$7.61M -$1.96M -56,866 -19%
TCM
38
Tekla Capital Management
Massachusetts
$7.16M
SAM
39
Sectoral Asset Management
Quebec, Canada
$6.66M +$602K +17,500 +9%
EAM
40
Eagle Asset Management
Florida
$6.56M +$424K +12,334 +6%
California Public Employees Retirement System
41
California Public Employees Retirement System
California
$6.5M
Axa
42
Axa
France
$6.45M -$671K -19,498 -9%
Swiss National Bank
43
Swiss National Bank
Switzerland
$6.04M +$482K +14,000 +8%
Rafferty Asset Management
44
Rafferty Asset Management
New York
$5.66M +$1.87M +54,207 +45%
Two Sigma Advisers
45
Two Sigma Advisers
New York
$5.54M -$3.35M -97,400 -36%
TRSOTSOK
46
Teachers Retirement System of the State of Kentucky
Kentucky
$5.52M
AllianceBernstein
47
AllianceBernstein
Tennessee
$4.99M +$10.3K +300 +0.2%
Marshall Wace
48
Marshall Wace
United Kingdom
$4.92M -$7.95M -231,089 -60%
CS
49
Candriam SCA
Luxembourg
$4.55M
Skandinaviska Enskilda Banken (SEB)
50
Skandinaviska Enskilda Banken (SEB)
Sweden
$4.46M -$2.2K -64 -0%

DNLI Hedge Fund Activity: Q1 2022 in Review

190 of the 6,340 institutional investors tracked by Wall St. Rank reported a position in Denali Therapeutics (DNLI) for Q1 2022, worth a combined $2.8B — down 26% from $3.8B a quarter earlier.

Sellers outnumbered buyers: 40 funds closed out of DNLI and 19 opened new positions — a net loss of 21 holders — while 69 trimmed existing stakes and 68 added.

The largest buyer was State Street, adding an estimated $27.5M. The largest seller was BAMCO Inc, cutting an estimated $11.7M.

  • 190 institutional investors held Denali Therapeutics (DNLI) as of Q1 2022, down from 213 in Q4 2021.
  • Funds reported $2.8B of Denali Therapeutics stock for Q1 2022, down 26% quarter-over-quarter.
  • 19 funds opened new Denali Therapeutics positions in Q1 2022 and 40 closed out, a net change of -21 holders.
  • The largest Denali Therapeutics buyer in Q1 2022 was State Street, an estimated $27.5M added.
  • The largest Denali Therapeutics seller in Q1 2022 was BAMCO Inc, an estimated $11.7M sold.

Based on aggregated 13F filings for Q1 2022.