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Denali Therapeutics

216 hedge funds and large institutions have $4.59B invested in Denali Therapeutics in 2021 Q1 according to their latest regulatory filings, with 41 funds opening new positions, 78 increasing their positions, 69 reducing their positions, and 26 closing their positions.

New
Increased
Maintained
Reduced
Closed

77% more call options, than puts

Call options by funds: $8.56M | Put options by funds: $4.85M

58% more first-time investments, than exits

New positions opened: 41 | Existing positions closed: 26

13% more repeat investments, than reductions

Existing positions increased: 78 | Existing positions reduced: 69

6% more funds holding

Funds holding: 204216 (+12)

0% more funds holding in top 10

Funds holding in top 10: 55 (0)

7.4% less ownership

Funds ownership: 73.91%66.51% (-7.4%)

25% less capital invested

Capital invested by funds: $6.13B → $4.59B (-$1.53B)

Holders
216
Holders Change
+12
Holders Change %
+5.88%
% of All Funds
3.79%
Holding in Top 10
5
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.09%
New
41
Increased
78
Reduced
69
Closed
26
Calls
$8.56M
Puts
$4.85M
Net Calls
+$3.71M
Net Calls Change
-$19.8M
Name Holding Trade Value Shares
Change
Change in
Stake
Dimensional Fund Advisors
26
Dimensional Fund Advisors
Texas
$24M -$2.11M -31,578 -7%
Jennison Associates
27
Jennison Associates
New York
$21.4M -$201K -3,000 -0.8%
Mitsubishi UFJ Trust & Banking
28
Mitsubishi UFJ Trust & Banking
Japan
$20.9M -$240K -3,590 -1%
Principal Financial Group
29
Principal Financial Group
Iowa
$19.3M +$8.71M +130,063 +63%
EC
30
Euclidean Capital
New York
$18.5M
EAM
31
Eagle Asset Management
Florida
$17.8M +$1.25M +18,676 +6%
UBS AM
32
UBS AM
Illinois
$17M -$7.46M -111,399 -27%
American Century Companies
33
American Century Companies
Missouri
$16.6M -$2.25M -33,646 -10%
N
34
Nuveen
North Carolina
$15.9M -$953K -14,241 -5%
MWNA
35
Marshall Wace North America
New York
$15.8M +$15.1M +225,720 +450%
Renaissance Technologies
36
Renaissance Technologies
New York
$15.2M +$17.8M +265,900 New
Bank of New York Mellon
37
Bank of New York Mellon
New York
$14.9M -$11.9M -178,006 -41%
Citadel Advisors
38
Citadel Advisors
Florida
$13.7M +$15.8M +235,671 +4,609%
CCM
39
CAAS Capital Management
New York
$13.3M +$3.5M +52,333 +29%
D.E. Shaw & Co
40
D.E. Shaw & Co
New York
$11.8M +$8.49M +126,802 +160%
Prudential Financial
41
Prudential Financial
New Jersey
$10.7M +$6.58M +98,225 +109%
Swiss National Bank
42
Swiss National Bank
Switzerland
$10.2M +$221K +3,300 +2%
Axa
43
Axa
France
$10.1M +$1.26M +18,788 +12%
California Public Employees Retirement System
44
California Public Employees Retirement System
California
$9.33M +$632K +9,434 +6%
TCM
45
Tekla Capital Management
Massachusetts
$8.57M +$5.2M +77,753 +107%
New York State Common Retirement Fund
46
New York State Common Retirement Fund
New York
$8.39M +$643K +9,605 +7%
TD Asset Management
47
TD Asset Management
Ontario, Canada
$8.04M +$469K +7,013 +5%
N
48
Natixis
France
$7.98M -$10.1M -151,000 -52%
TRSOTSOK
49
Teachers Retirement System of the State of Kentucky
Kentucky
$7.9M +$475K +7,100 +5%
Federated Hermes
50
Federated Hermes
Pennsylvania
$7.42M -$6.98M -104,240 -45%

DNLI Hedge Fund Activity: Q1 2021 in Review

216 of the 5,695 institutional investors tracked by Wall St. Rank reported a position in Denali Therapeutics (DNLI) for Q1 2021, worth a combined $4.59B — down 25% from $6.13B a quarter earlier.

Buyers outnumbered sellers: 41 funds opened new DNLI positions and 26 closed out — a net gain of 15 holders — while 78 added to existing stakes and 69 trimmed.

The largest buyer was Baillie Gifford & Co, adding an estimated $53.9M. The largest seller was Crestline Management, cutting an estimated $634M.

  • 216 institutional investors held Denali Therapeutics (DNLI) as of Q1 2021, up from 204 in Q4 2020.
  • Funds reported $4.59B of Denali Therapeutics stock for Q1 2021, down 25% quarter-over-quarter.
  • 41 funds opened new Denali Therapeutics positions in Q1 2021 and 26 closed out, a net change of +15 holders.
  • The largest Denali Therapeutics buyer in Q1 2021 was Baillie Gifford & Co, an estimated $53.9M added.
  • The largest Denali Therapeutics seller in Q1 2021 was Crestline Management, an estimated $634M sold.

Based on aggregated 13F filings for Q1 2021.