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Denali Therapeutics
DNLI

Overview Fund Activity

221 hedge funds and large institutions have $1.81B invested in Denali Therapeutics in 2025 Q1 according to their latest regulatory filings, with 36 funds opening new positions, 73 increasing their positions, 80 reducing their positions, and 35 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
221
Holders Change
-2
Holders Change %
-0.9%
% of All Funds
3%
Holding in Top 10
1
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-50%
% of All Funds
0.01%
New
36
Increased
73
Reduced
80
Closed
35
Calls
$848K
Puts
$515K
Net Calls
+$333K
Net Calls Change
-$267K

Top Buyers

1
UBS AM
UBS AM
Illinois
$92M
2
Wellington Management Group
Wellington Management Group
Massachusetts
$155M
3
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
$59.4M
4
Millennium Management
Millennium Management
New York
$20.3M
5
Squarepoint
Squarepoint
New York
$9.34M

Top Sellers

1
CCM
Camber Capital Management
Massachusetts
$17M
2
Point72 Asset Management
Point72 Asset Management
Connecticut
$0
3
Capital Research Global Investors
Capital Research Global Investors
California
$64.8M
4
Fidelity Investments
Fidelity Investments
Massachusetts
$101M
5
PAMP
Polar Asset Management Partners
Ontario, Canada
$285K
Name Holding Trade Value Shares
Change 		Shares
Change %
First Trust Advisors
226
First Trust Advisors
Illinois
– -$1.33M -65,442 Closed
DP
227
Diadema Partners
New Jersey
– -$1.22M -60,000 Closed
AG
228
Algert Global
California
– -$795K -39,015 Closed
FRM
229
Fox Run Management
Connecticut
– -$788K -38,668 Closed
Los Angeles Capital Management
230
Los Angeles Capital Management
California
– -$453K -22,222 Closed
UOC
231
UBS O'Connor
Illinois
– -$429K -21,039 Closed
BC
232
BIT Capital
Germany
– -$428K -21,011 Closed
BPC
233
Bryce Point Capital
New York
– -$419K -20,550 Closed
CM
234
Caption Management
Oklahoma
– -$406K -19,900 Closed
BHCM
235
Brevan Howard Capital Management
Jersey
– -$365K -17,917 Closed
Ameriprise
236
Ameriprise
Minnesota
– -$341K -16,743 Closed
BG
237
Bellevue Group
Switzerland
– -$320K -15,700 Closed
ACM
238
Aquatic Capital Management
Illinois
– -$320K -15,694 Closed
VPIM
239
Vanguard Personalized Indexing Management
California
– -$232K -11,377 Closed
PD
240
Point72 (DIFC)
United Arab Emirates
– -$152K -7,438 Closed
PHK
241
Point72 Hong Kong
Hong Kong
– -$64.7K -3,175 Closed
VEA
242
Virtus ETF Advisers
New York
– -$61.7K -3,029 Closed
RS
243
R Squared
Hong Kong
– -$11.8K -580 Closed
OC
244
Oarsman Capital
Wisconsin
– -$10.2K -500 Closed
PWMG
245
Private Wealth Management Group
New Jersey
– -$5.3K -260 Closed
BIG
246
Brooklyn Investment Group
New York
– -$3.51K -172 Closed
MAM
247
Meeder Asset Management
Ohio
– -$3.36K -165 Closed
AWM
248
Activest Wealth Management
Florida
– -$2.67K -131 Closed
AAP
249
Arax Advisory Partners
Colorado
– -$2.39K -117 Closed
Bessemer Group
250
Bessemer Group
New Jersey
– -$2K -110 Closed
7 8 9
10
11