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CRISPR Therapeutics

479 hedge funds and large institutions have $4.03B invested in CRISPR Therapeutics in 2025 Q4 according to their latest regulatory filings, with 95 funds opening new positions, 151 increasing their positions, 127 reducing their positions, and 52 closing their positions.

New
Increased
Maintained
Reduced
Closed

83% more first-time investments, than exits

New positions opened: 95 | Existing positions closed: 52

35% more call options, than puts

Call options by funds: $233M | Put options by funds: $172M

19% more repeat investments, than reductions

Existing positions increased: 151 | Existing positions reduced: 127

9% more funds holding

Funds holding: 440479 (+39)

0.82% more ownership

Funds ownership: 79.43%80.26% (+0.82%)

14% less capital invested

Capital invested by funds: $4.68B → $4.03B (-$657M)

14% less funds holding in top 10

Funds holding in top 10: 76 (-1)

Holders
479
Holders Change
+39
Holders Change %
+8.86%
% of All Funds
5.83%
Holding in Top 10
6
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-14.29%
% of All Funds
0.07%
New
95
Increased
151
Reduced
127
Closed
52
Calls
$233M
Puts
$172M
Net Calls
+$61M
Net Calls Change
+$25M
Name Holding Trade Value Shares
Change
Change in
Stake
AIM
1
ARK Investment Management
Florida
$552M +$44M +735,084 +8%
BlackRock
2
BlackRock
New York
$394M +$27.4M +458,033 +6%
OAG
3
Orbis Allan Gray
Bermuda
$312M +$58M +968,060 +19%
Capital International Investors
4
Capital International Investors
California
$309M +$14.6M +243,487 +4%
State Street
5
State Street
Massachusetts
$197M -$15.2M -253,793 -6%
T. Rowe Price Investment Management
6
T. Rowe Price Investment Management
Maryland
$169M -$3.35M -55,989 -2%
GP
7
GSK plc
$169M +$193M +3,220,627 New
UBS Group
8
UBS Group
Switzerland
$132M +$11.1M +185,088 +8%
Vanguard Group
9
Vanguard Group
Pennsylvania
$119M -$5.76M -96,251 -4%
Geode Capital Management
10
Geode Capital Management
Massachusetts
$118M +$6.47M +108,053 +5%
SOCM
11
SR One Capital Management
Pennsylvania
$107M
Sumitomo Mitsui Trust Group
12
Sumitomo Mitsui Trust Group
Japan
$103M -$12.3M -205,564 -10%
NAMA
13
Nikko Asset Management Americas
New York
$103M -$12.3M -205,564 -10%
Fidelity Investments
14
Fidelity Investments
Massachusetts
$102M +$4.09M +68,294 +4%
EC
15
EcoR1 Capital
California
$72.9M
Bank of America
16
Bank of America
North Carolina
$57.5M -$1.63M -27,232 -2%
NMC
17
NEA Management Company
Maryland
$55.5M
Charles Schwab
18
Charles Schwab
California
$54M +$2.66M +44,412 +5%
Dimensional Fund Advisors
19
Dimensional Fund Advisors
Texas
$47.6M +$1.8M +30,078 +3%
Loomis, Sayles & Company
20
Loomis, Sayles & Company
Massachusetts
$47.2M -$622K -10,383 -1%
Susquehanna International Group
21
Susquehanna International Group
Pennsylvania
$44.8M +$2.37M +39,647 +5%
Northern Trust
22
Northern Trust
Illinois
$39.6M -$1.49M -24,825 -3%
Morgan Stanley
23
Morgan Stanley
New York
$35M -$43.8M -730,799 -52%
Squarepoint
24
Squarepoint
New York
$30.5M +$34.8M +581,108 New
JP Morgan Chase
25
JP Morgan Chase
New York
$28.5M -$3.02M -50,462 -9%