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C4 Therapeutics
CCCC

Name Holding Trade Value Shares
Change 		Change in
Stake
State Street
1
State Street
Massachusetts
$58.4M +$54.2M +6,997,907 +4,504%
RCM
2
RA Capital Management
Massachusetts
$39.9M – – –
WA
3
Wasatch Advisors
Utah
$35.4M -$21.8M -2,810,470 -39%
LCM
4
Lynx1 Capital Management
Puerto Rico
$29.7M +$3.88M +500,266 +16%
CC
5
Commodore Capital
New York
$27.9M -$3.02M -389,616 -10%
Vanguard Group
6
Vanguard Group
Pennsylvania
$23.9M +$7.14M +920,627 +46%
SCM
7
Soleus Capital Management
Connecticut
$20.1M +$4.83M +623,000 +34%
Balyasny Asset Management
8
Balyasny Asset Management
Illinois
$19.9M +$5.67M +731,111 +43%
T. Rowe Price Associates
9
T. Rowe Price Associates
Maryland
$17.3M -$3.43M -443,003 -17%
Bank of America
10
Bank of America
North Carolina
$15.2M +$1.4M +180,061 +11%
SCM
11
Silverarc Capital Management
Massachusetts
$11.7M +$11.1M +1,435,931 New
Two Sigma Advisers
12
Two Sigma Advisers
New York
$10.7M +$9.61M +1,239,500 +1,705%
ACH
13
ArrowMark Colorado Holdings
Colorado
$10.6M -$6.55M -845,442 -40%
Goldman Sachs
14
Goldman Sachs
New York
$10.5M +$9.05M +1,167,729 +1,029%
TCM
15
TCG Crossover Management
California
$10.4M – – –
Two Sigma Investments
16
Two Sigma Investments
New York
$9.57M +$9.08M +1,171,840 New
BCLSI
17
Bain Capital Life Sciences Investors
Massachusetts
$9.33M -$3.88M -500,000 -30%
Point72 Asset Management
18
Point72 Asset Management
Connecticut
$7.41M -$8.18M -1,054,887 -54%
BlackRock
19
BlackRock
New York
$7.39M -$6.96M -898,427 -50%
Rafferty Asset Management
20
Rafferty Asset Management
New York
$6.81M +$6.46M +833,681 New
Citigroup
21
Citigroup
New York
$6.3M +$4.92M +635,255 +469%
CSS
22
Cubist Systematic Strategies
Connecticut
$6.25M +$3.51M +453,485 +146%
UBS Group
23
UBS Group
Switzerland
$5.69M +$3.24M +418,302 +150%
Dimensional Fund Advisors
24
Dimensional Fund Advisors
Texas
$5.16M +$4M +516,583 +447%
Millennium Management
25
Millennium Management
New York
$4.7M -$1.22M -157,014 -21%
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