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C4 Therapeutics
CCCC

Name Holding Trade Value Shares
Change 		Change in
Stake
Morgan Stanley
1
Morgan Stanley
New York
$41.4M -$701K -205,062 -2%
RCM
2
RA Capital Management
Massachusetts
$37.4M – – –
BlackRock
3
BlackRock
New York
$36.9M +$20M +5,848,192 +285%
LCM
4
Lynx1 Capital Management
Puerto Rico
$34.2M +$1.12M +327,789 +5%
SCM
5
Squadron Capital Management
Illinois
$33.6M +$16.9M +4,950,000 +220%
BCLSI
6
Bain Capital Life Sciences Investors
Massachusetts
$33.5M – – –
JP Morgan Chase
7
JP Morgan Chase
New York
$20.7M +$5.21M +1,524,370 +47%
Vanguard Capital Management
8
Vanguard Capital Management
Pennsylvania
$20.6M +$1.9M +555,879 +14%
Citadel Advisors
9
Citadel Advisors
Florida
$19.6M +$5.73M +1,676,565 +67%
Goldman Sachs
10
Goldman Sachs
New York
$16.5M +$3.91M +1,143,613 +48%
WA
11
Wasatch Advisors
Utah
$16.5M +$1.92M +560,883 +19%
Two Sigma Investments
12
Two Sigma Investments
New York
$16.2M +$1.48M +434,073 +14%
SCM
13
Soleus Capital Management
Connecticut
$15.8M -$1.46M -425,961 -11%
SCM
14
Silverarc Capital Management
Massachusetts
$14.2M +$3.83M +1,120,275 +59%
Bank of America
15
Bank of America
North Carolina
$12.4M +$1.02M +297,118 +13%
Geode Capital Management
16
Geode Capital Management
Massachusetts
$11.8M +$5.37M +1,571,120 +165%
IC
17
Ikarian Capital
Texas
$11.4M +$8.32M +2,433,000 New
State Street
18
State Street
Massachusetts
$9.88M +$5.93M +1,732,648 +452%
Acadian Asset Management
19
Acadian Asset Management
Massachusetts
$8.43M -$290K -84,715 -4%
CS
20
Candriam SCA
Luxembourg
$8.38M +$6.15M +1,796,937 New
D.E. Shaw & Co
21
D.E. Shaw & Co
New York
$8.13M +$2.33M +680,658 +64%
Susquehanna International Group
22
Susquehanna International Group
Pennsylvania
$8.09M +$1.52M +445,370 +35%
PSC
23
Patient Square Capital
California
$7.51M +$5.5M +1,608,815 New
HS
24
HighVista Strategies
Massachusetts
$6.3M +$4.61M +1,348,136 New
Renaissance Technologies
25
Renaissance Technologies
New York
$5.56M -$4.35M -1,271,987 -52%
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