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C4 Therapeutics
CCCC

Name Holding Trade Value Shares
Change 		Change in
Stake
WA
1
Wasatch Advisors
Utah
$40.3M +$2.03M +891,808 +14%
RCM
2
RA Capital Management
Massachusetts
$27.6M +$11.1M +4,878,000 New
CC
3
Commodore Capital
New York
$21.5M +$8.66M +3,800,000 New
LCM
4
Lynx1 Capital Management
Puerto Rico
$17.7M +$4.82M +2,115,166 +208%
T. Rowe Price Associates
5
T. Rowe Price Associates
Maryland
$14.5M +$848K +372,021 +17%
ACH
6
ArrowMark Colorado Holdings
Colorado
$12.1M -$546K -239,425 -10%
Vanguard Group
7
Vanguard Group
Pennsylvania
$11.3M +$170K +74,545 +4%
Point72 Asset Management
8
Point72 Asset Management
Connecticut
$11.1M +$4.44M +1,945,338 +12,142%
SCM
9
Soleus Capital Management
Connecticut
$10.4M -$1.95M -856,024 -32%
BlackRock
10
BlackRock
New York
$10.2M -$666K -291,905 -14%
Balyasny Asset Management
11
Balyasny Asset Management
Illinois
$9.63M +$3.89M +1,704,269 New
Bank of America
12
Bank of America
North Carolina
$9.46M +$3.72M +1,629,756 +3,594%
BCLSI
13
Bain Capital Life Sciences Investors
Massachusetts
$9.28M – – –
TCM
14
TCG Crossover Management
California
$7.21M – – –
Marshall Wace
15
Marshall Wace
United Kingdom
$6.35M +$2.56M +1,123,061 New
Susquehanna International Group
16
Susquehanna International Group
Pennsylvania
$5.66M +$1.92M +840,650 +519%
Millennium Management
17
Millennium Management
New York
$4.14M -$992K -435,227 -37%
Invesco
18
Invesco
Georgia
$3.91M +$1.45M +635,691 +1,127%
Geode Capital Management
19
Geode Capital Management
Massachusetts
$2.73M +$60.3K +26,444 +6%
Renaissance Technologies
20
Renaissance Technologies
New York
$2.4M +$152K +66,712 +19%
Morgan Stanley
21
Morgan Stanley
New York
$2.32M +$223K +97,605 +31%
CSS
22
Cubist Systematic Strategies
Connecticut
$1.76M +$555K +243,230 +357%
UBS Group
23
UBS Group
Switzerland
$1.57M -$98.6K -43,234 -13%
Charles Schwab
24
Charles Schwab
California
$1.43M +$10.2K +4,458 +2%
D.E. Shaw & Co
25
D.E. Shaw & Co
New York
$1.38M -$434K -190,472 -44%
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