Two Sigma Advisers
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Two Sigma Advisers’s C4 Therapeutics CCCC Stock Holding History

Two Sigma Advisers’s Portfolio CCCC Stock Details CCCC Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		– Sell
-1,068,200
Closed -$2.04M – 383
2025
Q4 		$2.04M Buy
1,068,200
+305,100
+40% +$723K ﹤0.01% 1180
2025
Q3 		$1.69M Sell
763,100
-48,300
-6% -$116K ﹤0.01% 1205
2025
Q2 		$1.16M Buy
811,400
+10,800
+1% +$15.7K ﹤0.01% 1368
2025
Q1 		$1.28M Sell
800,600
-83,700
-9% -$250K ﹤0.01% 1353
2024
Q4 		$3.18M Sell
884,300
-181,200
-17% -$901K 0.01% 902
2024
Q3 		$6.07M Sell
1,065,500
-326,400
-23% -$1.96M 0.01% 646
2024
Q2 		$6.43M Buy
1,391,900
+79,700
+6% +$475K 0.01% 677
2024
Q1 		$10.7M Buy
1,312,200
+1,239,500
+1,705% +$9.61M 0.02% 516
2023
Q4 		$411K Sell
72,700
-633,400
-90% -$1.44M ﹤0.01% 1993
2023
Q3 		$1.31M Sell
706,100
-300
-0% -$915 ﹤0.01% 1411
2023
Q2 		$1.94M Buy
706,400
+306,100
+76% +$984K ﹤0.01% 1215
2023
Q1 		$1.26M Buy
400,300
+138,800
+53% +$817K ﹤0.01% 1515
2022
Q4 		$1.54M Sell
261,500
-10,100
-4% -$83.7K ﹤0.01% 1372
2022
Q3 		$2.38M Sell
271,600
-77,900
-22% -$809K 0.01% 1079
2022
Q2 		$2.63M Buy
349,500
+307,300
+728% +$2.7M 0.01% 1075
2022
Q1 		$1.02M Buy
+42,200
New +$1.02M ﹤0.01% 1626

Other funds holding CCCC

Morgan Stanley
Morgan Stanley New York $1.66T AUM 25.57% 1-Year Est. Return
RCM
RA Capital Management Boston, Massachusetts $9.44B AUM 157.3% 1-Year Est. Return
BCLSI
Bain Capital Life Sciences Investors Boston, Massachusetts $1.11B AUM 171.34% 1-Year Est. Return
LCM
Lynx1 Capital Management San Juan, Puerto Rico $633M AUM 173.22% 1-Year Est. Return
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
SCM
Soleus Capital Management Greenwich, Connecticut $2.47B AUM 115.63% 1-Year Est. Return
Two Sigma Investments
Two Sigma Investments New York $124B AUM 33.93% 1-Year Est. Return
WA
Wasatch Advisors Salt Lake City, Utah $15.3B AUM 25.06% 1-Year Est. Return
JP Morgan Chase
JP Morgan Chase New York $1.56T AUM 27.86% 1-Year Est. Return
Citadel Advisors
Citadel Advisors Miami, Florida $618B AUM 30.34% 1-Year Est. Return

Two Sigma Advisers's CCCC Position: Q1 2026 in Review

Two Sigma Advisers sold out of C4 Therapeutics (CCCC) in Q1 2026, closing a stake of 1,068,200 shares — an estimated $2.04M sold.

Two Sigma Advisers first reported a position in CCCC in Q1 2022 and held it in 16 quarters. The position peaked at $10.7M in Q1 2024. 123 funds tracked by Wall St. Rank hold CCCC as of Q1 2026.

  • Two Sigma Advisers reported no remaining C4 Therapeutics position as of Q1 2026 after selling out during the quarter.
  • Two Sigma Advisers sold 1,068,200 C4 Therapeutics shares in Q1 2026, an estimated $2.04M.
  • Two Sigma Advisers first reported a position in C4 Therapeutics in Q1 2022 and held it in 16 quarters.
  • Two Sigma Advisers's C4 Therapeutics position peaked at $10.7M in Q1 2024.
  • 123 funds tracked by Wall St. Rank held C4 Therapeutics as of Q1 2026.

Based on Two Sigma Advisers's 13F filing for Q1 2026.