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C4 Therapeutics

97 hedge funds and large institutions have $117M invested in C4 Therapeutics in 2025 Q3 according to their latest regulatory filings, with 21 funds opening new positions, 26 increasing their positions, 38 reducing their positions, and 26 closing their positions.

New
Increased
Maintained
Reduced
Closed

49% more capital invested

Capital invested by funds: $78.2M → $117M (+$38.4M)

25% more call options, than puts

Call options by funds: $806K | Put options by funds: $645K

0% more funds holding in top 10

Funds holding in top 10: 11 (0)

3.2% less ownership

Funds ownership: 77.02%73.82% (-3.2%)

5% less funds holding

Funds holding: 10297 (-5)

19% less first-time investments, than exits

New positions opened: 21 | Existing positions closed: 26

32% less repeat investments, than reductions

Existing positions increased: 26 | Existing positions reduced: 38

Holders
97
Holders Change
-5
Holders Change %
-4.9%
% of All Funds
1.27%
Holding in Top 10
1
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.01%
New
21
Increased
26
Reduced
38
Closed
26
Calls
$806K
Puts
$645K
Net Calls
+$161K
Net Calls Change
+$64K
Name Holding Trade Value Shares
Change
Change in
Stake
LCM
1
Lynx1 Capital Management
Puerto Rico
$15.8M
SCM
2
Soleus Capital Management
Connecticut
$15.7M +$180K +75,000 +1%
O
3
OrbiMed
New York
$11.6M -$3.83M -1,595,154 -23%
Morgan Stanley
4
Morgan Stanley
New York
$11M +$523K +217,844 +5%
WA
5
Wasatch Advisors
Utah
$10.8M -$6.17M -2,571,921 -35%
Vanguard Group
6
Vanguard Group
Pennsylvania
$7.09M +$417K +173,535 +6%
Bank of America
7
Bank of America
North Carolina
$4.56M +$108K +45,158 +2%
Millennium Management
8
Millennium Management
New York
$4.29M +$2M +832,883 +76%
SCM
9
Silverarc Capital Management
Massachusetts
$4.21M +$4.55M +1,897,383 New
BlackRock
10
BlackRock
New York
$3.54M -$559K -232,975 -13%
BCLSI
11
Bain Capital Life Sciences Investors
Massachusetts
$2.47M
Renaissance Technologies
12
Renaissance Technologies
New York
$2.08M -$375K -156,238 -14%
TCM
13
Tang Capital Management
California
$2M
Two Sigma Investments
14
Two Sigma Investments
New York
$1.85M +$363K +151,127 +22%
Two Sigma Advisers
15
Two Sigma Advisers
New York
$1.69M -$116K -48,300 -6%
Geode Capital Management
16
Geode Capital Management
Massachusetts
$1.61M -$47.4K -19,749 -3%
Susquehanna International Group
17
Susquehanna International Group
Pennsylvania
$1.14M +$899K +374,381 +265%
Jacobs Levy Equity Management
18
Jacobs Levy Equity Management
New Jersey
$1.12M +$147K +61,410 +14%
Citadel Advisors
19
Citadel Advisors
Florida
$1.07M +$1.16M +481,449 New
Goldman Sachs
20
Goldman Sachs
New York
$1.02M -$1.01M -420,365 -48%
SC
21
Shay Capital
New York
$932K +$1.01M +420,000 New
Charles Schwab
22
Charles Schwab
California
$778K +$44.9K +18,709 +6%
Dimensional Fund Advisors
23
Dimensional Fund Advisors
Texas
$775K -$198K -82,599 -19%
State Street
24
State Street
Massachusetts
$638K
SPS
25
Susquehanna Portfolio Strategies
Pennsylvania
$604K +$348K +145,153 +114%

CCCC Hedge Fund Activity: Q3 2025 in Review

97 of the 7,620 institutional investors tracked by Wall St. Rank reported a position in C4 Therapeutics (CCCC) for Q3 2025, worth a combined $117M — up 49% from $78.2M a quarter earlier.

Sellers outnumbered buyers: 26 funds closed out of CCCC and 21 opened new positions — a net loss of 5 holders — while 38 trimmed existing stakes and 26 added.

The largest buyer was Silverarc Capital Management, opening a new position worth an estimated $4.55M. The largest seller was Wasatch Advisors, cutting an estimated $6.17M.

  • 97 institutional investors held C4 Therapeutics (CCCC) as of Q3 2025, down from 102 in Q2 2025.
  • Funds reported $117M of C4 Therapeutics stock for Q3 2025, up 49% quarter-over-quarter.
  • 21 funds opened new C4 Therapeutics positions in Q3 2025 and 26 closed out, a net change of -5 holders.
  • The largest C4 Therapeutics buyer in Q3 2025 was Silverarc Capital Management, an estimated $4.55M added.
  • The largest C4 Therapeutics seller in Q3 2025 was Wasatch Advisors, an estimated $6.17M sold.

Based on aggregated 13F filings for Q3 2025.