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C4 Therapeutics
CCCC

Overview Fund Activity

101 hedge funds and large institutions have $78.2M invested in C4 Therapeutics in 2025 Q2 according to their latest regulatory filings, with 26 funds opening new positions, 32 increasing their positions, 32 reducing their positions, and 39 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
101
Holders Change
-13
Holders Change %
-11.4%
% of All Funds
1.36%
Holding in Top 10
1
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.01%
New
26
Increased
32
Reduced
32
Closed
39
Calls
$111K
Puts
$14K
Net Calls
+$97K
Net Calls Change
-$26K

Top Buyers

1
Millennium Management
1
Millennium Management
New York
$1.57M
2
Renaissance Technologies
2
Renaissance Technologies
New York
$1.56M
3
Morgan Stanley
3
Morgan Stanley
New York
$6.8M
4
WA
4
Wasatch Advisors
Utah
$10.6M
5
Jane Street
5
Jane Street
New York
$704K

Top Sellers

1
BlackRock
1
BlackRock
New York
$2.61M
2
SC
2
Samlyn Capital
New York
$0
3
Adage Capital Partners
3
Adage Capital Partners
Massachusetts
$286K
4
ACH
4
ArrowMark Colorado Holdings
Colorado
$292K
5
SCM
5
Silverarc Capital Management
Massachusetts
$0
Name Holding Trade Value Shares
Change 		Shares
Change %
WA
1
Wasatch Advisors
Utah
$10.6M +$1M +700,253 +10%
LCM
2
Lynx1 Capital Management
Puerto Rico
$10.2M – – –
SCM
3
Soleus Capital Management
Connecticut
$9.98M – – –
O
4
OrbiMed
New York
$9.77M – – –
Morgan Stanley
5
Morgan Stanley
New York
$6.8M +$1.01M +708,859 +18%
Vanguard Group
6
Vanguard Group
Pennsylvania
$4.32M -$505K -352,858 -10%
Bank of America
7
Bank of America
North Carolina
$2.87M +$24.6K +17,180 +0.9%
BlackRock
8
BlackRock
New York
$2.61M -$4.94M -3,455,799 -65%
BCLSI
9
Bain Capital Life Sciences Investors
Massachusetts
$1.59M – – –
Millennium Management
10
Millennium Management
New York
$1.57M +$1.48M +1,035,445 +1,571%
Renaissance Technologies
11
Renaissance Technologies
New York
$1.56M +$1.26M +878,688 +410%
TCM
12
Tang Capital Management
California
$1.29M – – –
Goldman Sachs
13
Goldman Sachs
New York
$1.26M +$368K +257,538 +41%
Two Sigma Advisers
14
Two Sigma Advisers
New York
$1.16M +$15.4K +10,800 +1%
Geode Capital Management
15
Geode Capital Management
Massachusetts
$1.07M -$980K -685,235 -48%
Two Sigma Investments
16
Two Sigma Investments
New York
$978K +$242K +168,996 +33%
UBS Group
17
UBS Group
Switzerland
$818K -$430K -300,744 -34%
Jane Street
18
Jane Street
New York
$704K +$686K +480,035 +3,817%
Jacobs Levy Equity Management
19
Jacobs Levy Equity Management
New Jersey
$632K -$366K -255,918 -37%
Dimensional Fund Advisors
20
Dimensional Fund Advisors
Texas
$617K -$118K -82,267 -16%
AQR Capital Management
21
AQR Capital Management
Connecticut
$549K +$348K +243,257 +173%
Charles Schwab
22
Charles Schwab
California
$475K -$204K -142,946 -30%
State Street
23
State Street
Massachusetts
$411K -$1.34M -937,045 -77%
CSS
24
Cubist Systematic Strategies
Connecticut
$343K +$343K +239,959 New
Royal Bank of Canada
25
Royal Bank of Canada
Ontario, Canada
$342K +$334K +233,392 +4,194%
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