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C4 Therapeutics

102 hedge funds and large institutions have $78.2M invested in C4 Therapeutics in 2025 Q2 according to their latest regulatory filings, with 27 funds opening new positions, 32 increasing their positions, 32 reducing their positions, and 39 closing their positions.

New
Increased
Maintained
Reduced
Closed

693% more call options, than puts

Call options by funds: $111K | Put options by funds: $14K

0% more funds holding in top 10

Funds holding in top 10: 11 (0)

0% more repeat investments, than reductions

Existing positions increased: 32 | Existing positions reduced: 32

11% less funds holding

Funds holding: 114102 (-12)

13.28% less ownership

Funds ownership: 90.3%77.02% (-13%)

24% less capital invested

Capital invested by funds: $103M → $78.2M (-$24.4M)

31% less first-time investments, than exits

New positions opened: 27 | Existing positions closed: 39

Holders
102
Holders Change
-12
Holders Change %
-10.53%
% of All Funds
1.34%
Holding in Top 10
1
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.01%
New
27
Increased
32
Reduced
32
Closed
39
Calls
$111K
Puts
$14K
Net Calls
+$97K
Net Calls Change
-$26K
Name Holding Trade Value Shares
Change
Change in
Stake
WA
1
Wasatch Advisors
Utah
$10.6M +$1.02M +700,253 +10%
LCM
2
Lynx1 Capital Management
Puerto Rico
$10.2M
SCM
3
Soleus Capital Management
Connecticut
$9.98M
O
4
OrbiMed
New York
$9.77M
Morgan Stanley
5
Morgan Stanley
New York
$6.8M +$1.03M +708,859 +18%
Vanguard Group
6
Vanguard Group
Pennsylvania
$4.32M -$513K -352,858 -10%
Bank of America
7
Bank of America
North Carolina
$2.87M +$25K +17,180 +0.9%
BlackRock
8
BlackRock
New York
$2.61M -$5.03M -3,455,799 -65%
BCLSI
9
Bain Capital Life Sciences Investors
Massachusetts
$1.59M
Millennium Management
10
Millennium Management
New York
$1.57M +$1.51M +1,035,445 +1,571%
Renaissance Technologies
11
Renaissance Technologies
New York
$1.56M +$1.28M +878,688 +410%
TCM
12
Tang Capital Management
California
$1.29M
Goldman Sachs
13
Goldman Sachs
New York
$1.26M +$375K +257,538 +41%
Two Sigma Advisers
14
Two Sigma Advisers
New York
$1.16M +$15.7K +10,800 +1%
Geode Capital Management
15
Geode Capital Management
Massachusetts
$1.07M -$997K -685,235 -48%
Two Sigma Investments
16
Two Sigma Investments
New York
$978K +$246K +168,996 +33%
UBS Group
17
UBS Group
Switzerland
$818K -$437K -300,744 -34%
Jane Street
18
Jane Street
New York
$704K +$698K +480,035 +3,817%
Jacobs Levy Equity Management
19
Jacobs Levy Equity Management
New Jersey
$632K -$372K -255,918 -37%
Dimensional Fund Advisors
20
Dimensional Fund Advisors
Texas
$617K -$120K -82,267 -16%
AQR Capital Management
21
AQR Capital Management
Connecticut
$549K +$354K +243,257 +173%
Charles Schwab
22
Charles Schwab
California
$475K -$208K -142,946 -30%
State Street
23
State Street
Massachusetts
$411K -$1.36M -937,045 -77%
CSS
24
Cubist Systematic Strategies
Connecticut
$343K +$349K +239,959 New
Royal Bank of Canada
25
Royal Bank of Canada
Ontario, Canada
$342K +$339K +233,392 +4,194%

CCCC Hedge Fund Activity: Q2 2025 in Review

102 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in C4 Therapeutics (CCCC) for Q2 2025, worth a combined $78.2M — down 24% from $103M a quarter earlier.

Sellers outnumbered buyers: 39 funds closed out of CCCC and 27 opened new positions — a net loss of 12 holders — while 32 trimmed existing stakes and 32 added.

The largest buyer was Millennium Management, adding an estimated $1.51M. The largest seller was BlackRock, cutting an estimated $5.03M.

  • 102 institutional investors held C4 Therapeutics (CCCC) as of Q2 2025, down from 114 in Q1 2025.
  • Funds reported $78.2M of C4 Therapeutics stock for Q2 2025, down 24% quarter-over-quarter.
  • 27 funds opened new C4 Therapeutics positions in Q2 2025 and 39 closed out, a net change of -12 holders.
  • The largest C4 Therapeutics buyer in Q2 2025 was Millennium Management, an estimated $1.51M added.
  • The largest C4 Therapeutics seller in Q2 2025 was BlackRock, an estimated $5.03M sold.

Based on aggregated 13F filings for Q2 2025.