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BPMC

Blueprint Medicines

Delisted

BPMC was delisted on the 17th of July, 2025.

280 hedge funds and large institutions have $6.29B invested in Blueprint Medicines in 2021 Q4 according to their latest regulatory filings, with 30 funds opening new positions, 98 increasing their positions, 108 reducing their positions, and 35 closing their positions.

New
Increased
Maintained
Reduced
Closed

3% more capital invested

Capital invested by funds: $6.12B → $6.29B (+$172M)

9% less repeat investments, than reductions

Existing positions increased: 98 | Existing positions reduced: 108

1.45% less ownership

Funds ownership: 101.83%100.38% (-1.5%)

3% less funds holding

Funds holding: 288280 (-8)

14% less first-time investments, than exits

New positions opened: 30 | Existing positions closed: 35

20% less call options, than puts

Call options by funds: $9.29M | Put options by funds: $11.7M

25% less funds holding in top 10

Funds holding in top 10: 86 (-2)

Holders
280
Holders Change
-8
Holders Change %
-2.78%
% of All Funds
4.31%
Holding in Top 10
6
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-25%
% of All Funds
0.09%
New
30
Increased
98
Reduced
108
Closed
35
Calls
$9.29M
Puts
$11.7M
Net Calls
-$2.37M
Net Calls Change
-$20.2M
Name Holding Trade Value Shares
Change
Change in
Stake
Canada Life
201
Canada Life
Manitoba, Canada
$335K +$9.1K +87 +3%
SCA
202
STALEY CAPITAL ADVISERS
Pennsylvania
$321K
LNWWM
203
Laird Norton Wetherby Wealth Management
California
$308K +$2.41K +23 +0.8%
X
204
Xponance
Pennsylvania
$303K +$2.3K +22 +0.8%
FC
205
FORA Capital
Florida
$297K +$290K +2,773 New
TRCT
206
Tower Research Capital (TRC)
New York
$290K +$2.51K +24 +0.9%
CIBC Asset Management
207
CIBC Asset Management
Ontario, Canada
$272K +$17.6K +168 +7%
Nisa Investment Advisors
208
Nisa Investment Advisors
Missouri
$260K +$107K +1,025 +44%
LPL Financial
209
LPL Financial
California
$251K +$1.99K +19 +0.8%
N
210
Natixis
France
$245K -$15.6K -149 -6%
Cerity Partners
211
Cerity Partners
New York
$245K +$9.83K +94 +4%
FRM
212
Fox Run Management
Connecticut
$239K +$233K +2,228 New
FL
213
Fort LP
Maryland
$227K -$162K -1,553 -42%
FCI
214
Financial Counselors Inc
Kansas
$216K +$1.05K +10 +0.5%
CG
215
Cutler Group
California
$214K -$105K -1,000 -33%
IB
216
Intrust Bank
Kansas
$208K -$12.7K -121 -6%
Group One Trading
217
Group One Trading
Illinois
$161K -$418K -4,000 -73%
Amundi
218
Amundi
France
$148K
VanEck Associates
219
VanEck Associates
New York
$143K +$18.4K +176 +15%
Fifth Third Bancorp
220
Fifth Third Bancorp
Ohio
$115K -$7.11K -68 -6%
LC
221
Lindbrook Capital
California
$103K +$100K +956 +95,600%
BFEC
222
Benjamin F. Edwards & Company
Missouri
$97K +$15.7K +150 +20%
TIM
223
Tortoise Investment Management
New York
$93K
ETC
224
Exchange Traded Concepts
Oklahoma
$71K +$23.5K +225 +52%
CT
225
Clearstead Trust
Maine
$55K

BPMC Hedge Fund Activity: Q4 2021 in Review

280 of the 6,498 institutional investors tracked by Wall St. Rank reported a position in Blueprint Medicines (BPMC) for Q4 2021, worth a combined $6.29B — up 2.8% from $6.12B a quarter earlier.

Sellers outnumbered buyers: 35 funds closed out of BPMC and 30 opened new positions — a net loss of 5 holders — while 108 trimmed existing stakes and 98 added.

The largest buyer was Marshall Wace, adding an estimated $96.6M. The largest seller was Fidelity Investments, cutting an estimated $90.3M.

  • 280 institutional investors held Blueprint Medicines (BPMC) as of Q4 2021, down from 288 in Q3 2021.
  • Funds reported $6.29B of Blueprint Medicines stock for Q4 2021, up 2.8% quarter-over-quarter.
  • 30 funds opened new Blueprint Medicines positions in Q4 2021 and 35 closed out, a net change of -5 holders.
  • The largest Blueprint Medicines buyer in Q4 2021 was Marshall Wace, an estimated $96.6M added.
  • The largest Blueprint Medicines seller in Q4 2021 was Fidelity Investments, an estimated $90.3M sold.

Based on aggregated 13F filings for Q4 2021.