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BPMC

Blueprint Medicines

Delisted

BPMC was delisted on the 17th of July, 2025.

280 hedge funds and large institutions have $6.29B invested in Blueprint Medicines in 2021 Q4 according to their latest regulatory filings, with 30 funds opening new positions, 98 increasing their positions, 108 reducing their positions, and 35 closing their positions.

New
Increased
Maintained
Reduced
Closed

3% more capital invested

Capital invested by funds: $6.12B → $6.29B (+$172M)

9% less repeat investments, than reductions

Existing positions increased: 98 | Existing positions reduced: 108

1.45% less ownership

Funds ownership: 101.83%100.38% (-1.5%)

3% less funds holding

Funds holding: 288280 (-8)

14% less first-time investments, than exits

New positions opened: 30 | Existing positions closed: 35

20% less call options, than puts

Call options by funds: $9.29M | Put options by funds: $11.7M

25% less funds holding in top 10

Funds holding in top 10: 86 (-2)

Holders
280
Holders Change
-8
Holders Change %
-2.78%
% of All Funds
4.31%
Holding in Top 10
6
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-25%
% of All Funds
0.09%
New
30
Increased
98
Reduced
108
Closed
35
Calls
$9.29M
Puts
$11.7M
Net Calls
-$2.37M
Net Calls Change
-$20.2M
Name Holding Trade Value Shares
Change
Change in
Stake
Canada Pension Plan Investment Board
176
Canada Pension Plan Investment Board
Ontario, Canada
$662K +$32.6K +312 +5%
EAMA
177
EFG Asset Management (Americas)
Florida
$654K +$12.7K +121 +2%
PNC Financial Services Group
178
PNC Financial Services Group
Pennsylvania
$647K -$12.9K -123 -2%
William Blair & Company
179
William Blair & Company
Illinois
$638K +$41.9K +401 +7%
ZCM
180
Ziegler Capital Management
Illinois
$632K -$268K -2,566 -30%
EF
181
Empirical Finance
Pennsylvania
$611K -$444K -4,243 -43%
ZCM
182
Zebra Capital Management
Connecticut
$596K -$214K -2,048 -27%
VC
183
Veracity Capital
Georgia
$548K -$105K -1,000 -16%
SCA
184
Spearhead Capital Advisors
Florida
$534K +$25.5K +244 +5%
JMPWA
185
JP Morgan Private Wealth Advisors
California
$533K
CAM
186
Cresset Asset Management
Illinois
$529K +$515K +4,926 New
DCM
187
Dupont Capital Management
Delaware
$518K -$853K -8,155 -63%
HC
188
Henshaw Capital
Massachusetts
$515K
AIP
189
Ameritas Investment Partners
Nebraska
$490K
HW
190
Hancock Whitney
Mississippi
$485K -$55K -526 -10%
VVP
191
Venture Visionary Partners
Ohio
$466K
OSAM
192
O'Shaughnessy Asset Management
Connecticut
$453K -$16.6K -159 -4%
P
193
Pitcairn
Pennsylvania
$449K -$131K -1,257 -23%
VEA
194
Virtus ETF Advisers
New York
$403K -$161K -1,540 -29%
ZCA
195
Zeke Capital Advisors
Pennsylvania
$396K -$14.9K -142 -4%
AA
196
ALPS Advisors
Colorado
$394K +$4.6K +44 +1%
HIA
197
Harbor Investment Advisory
Maryland
$373K
IMRF
198
Illinois Municipal Retirement Fund
Illinois
$367K +$359K +3,430 New
Osaic Holdings
199
Osaic Holdings
Arizona
$354K -$21.1K -202 -6%
Mackenzie Financial
200
Mackenzie Financial
Ontario, Canada
$341K -$525K -5,019 -61%

BPMC Hedge Fund Activity: Q4 2021 in Review

280 of the 6,498 institutional investors tracked by Wall St. Rank reported a position in Blueprint Medicines (BPMC) for Q4 2021, worth a combined $6.29B — up 2.8% from $6.12B a quarter earlier.

Sellers outnumbered buyers: 35 funds closed out of BPMC and 30 opened new positions — a net loss of 5 holders — while 108 trimmed existing stakes and 98 added.

The largest buyer was Marshall Wace, adding an estimated $96.6M. The largest seller was Fidelity Investments, cutting an estimated $90.3M.

  • 280 institutional investors held Blueprint Medicines (BPMC) as of Q4 2021, down from 288 in Q3 2021.
  • Funds reported $6.29B of Blueprint Medicines stock for Q4 2021, up 2.8% quarter-over-quarter.
  • 30 funds opened new Blueprint Medicines positions in Q4 2021 and 35 closed out, a net change of -5 holders.
  • The largest Blueprint Medicines buyer in Q4 2021 was Marshall Wace, an estimated $96.6M added.
  • The largest Blueprint Medicines seller in Q4 2021 was Fidelity Investments, an estimated $90.3M sold.

Based on aggregated 13F filings for Q4 2021.