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BPMC

Blueprint Medicines

Delisted

BPMC was delisted on the 17th of July, 2025.

281 hedge funds and large institutions have $5.14B invested in Blueprint Medicines in 2021 Q2 according to their latest regulatory filings, with 54 funds opening new positions, 109 increasing their positions, 72 reducing their positions, and 35 closing their positions.

New
Increased
Maintained
Reduced
Closed

54% more first-time investments, than exits

New positions opened: 54 | Existing positions closed: 35

51% more repeat investments, than reductions

Existing positions increased: 109 | Existing positions reduced: 72

7% more funds holding

Funds holding: 263281 (+18)

0.71% less ownership

Funds ownership: 100.96%100.24% (-0.71%)

10% less capital invested

Capital invested by funds: $5.69B → $5.14B (-$550M)

29% less funds holding in top 10

Funds holding in top 10: 75 (-2)

39% less call options, than puts

Call options by funds: $8.99M | Put options by funds: $14.8M

Holders
281
Holders Change
+18
Holders Change %
+6.84%
% of All Funds
4.89%
Holding in Top 10
5
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-28.57%
% of All Funds
0.09%
New
54
Increased
109
Reduced
72
Closed
35
Calls
$8.99M
Puts
$14.8M
Net Calls
-$5.78M
Net Calls Change
+$2.96M
Name Holding Trade Value Shares
Change
Change in
Stake
PNC Financial Services Group
176
PNC Financial Services Group
Pennsylvania
$534K -$71.9K -785 -11%
QSS
177
Quantitative Systematic Strategies
Florida
$527K -$628K -6,853 -53%
VEA
178
Virtus ETF Advisers
New York
$509K +$41.4K +452 +8%
HW
179
Hancock Whitney
Mississippi
$447K +$9.71K +106 +2%
DF
180
Donoghue Forlines
Massachusetts
$443K +$13.8K +151 +3%
SM
181
SG3 Management
Puerto Rico
$440K +$458K +5,000 New
EAMA
182
EFG Asset Management (Americas)
Florida
$438K +$116K +1,271 +34%
JMPWA
183
JP Morgan Private Wealth Advisors
California
$437K +$550 +6 +0.1%
FL
184
Fort LP
Maryland
$433K -$107K -1,166 -19%
HC
185
Henshaw Capital
Massachusetts
$423K +$96.4K +1,052 +28%
US Bancorp
186
US Bancorp
Minnesota
$420K +$19.3K +211 +5%
AIP
187
Ameritas Investment Partners
Nebraska
$407K +$11.5K +125 +3%
SCA
188
Spearhead Capital Advisors
Florida
$396K +$49.9K +545 +14%
VVP
189
Venture Visionary Partners
Ohio
$382K +$399K +4,354 New
BC
190
Bridgefront Capital
Texas
$344K +$359K +3,915 New
ZCA
191
Zeke Capital Advisors
Pennsylvania
$338K +$44.4K +485 +14%
SRAM
192
Spouting Rock Asset Management
Pennsylvania
$337K +$39.9K +435 +13%
CG
193
Cutler Group
California
$320K
OSAM
194
O'Shaughnessy Asset Management
Connecticut
$310K -$3.21K -35 -1%
HIA
195
Harbor Investment Advisory
Maryland
$307K +$17K +186 +6%
ESCM
196
Echo Street Capital Management
New York
$304K -$345K -3,761 -52%
Osaic Holdings
197
Osaic Holdings
Arizona
$303K +$90.5K +988 +40%
NIPH
198
NN Investment Partners Holdings
Netherlands
$290K +$302K +3,300 New
Stifel Financial
199
Stifel Financial
Missouri
$289K +$77.1K +841 +34%
AA
200
ALPS Advisors
Colorado
$288K

BPMC Hedge Fund Activity: Q2 2021 in Review

281 of the 5,745 institutional investors tracked by Wall St. Rank reported a position in Blueprint Medicines (BPMC) for Q2 2021, worth a combined $5.14B — down 9.7% from $5.69B a quarter earlier.

Buyers outnumbered sellers: 54 funds opened new BPMC positions and 35 closed out — a net gain of 19 holders — while 109 added to existing stakes and 72 trimmed.

The largest buyer was Wellington Management Group, adding an estimated $62.4M. The largest seller was Lone Pine Capital, exiting entirely with an estimated $263M sold.

  • 281 institutional investors held Blueprint Medicines (BPMC) as of Q2 2021, up from 263 in Q1 2021.
  • Funds reported $5.14B of Blueprint Medicines stock for Q2 2021, down 9.7% quarter-over-quarter.
  • 54 funds opened new Blueprint Medicines positions in Q2 2021 and 35 closed out, a net change of +19 holders.
  • The largest Blueprint Medicines buyer in Q2 2021 was Wellington Management Group, an estimated $62.4M added.
  • The largest Blueprint Medicines seller in Q2 2021 was Lone Pine Capital, an estimated $263M sold.

Based on aggregated 13F filings for Q2 2021.