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BPMC

Blueprint Medicines

Delisted

BPMC was delisted on the 17th of July, 2025.

280 hedge funds and large institutions have $6.29B invested in Blueprint Medicines in 2021 Q4 according to their latest regulatory filings, with 30 funds opening new positions, 98 increasing their positions, 108 reducing their positions, and 35 closing their positions.

New
Increased
Maintained
Reduced
Closed

3% more capital invested

Capital invested by funds: $6.12B → $6.29B (+$172M)

9% less repeat investments, than reductions

Existing positions increased: 98 | Existing positions reduced: 108

1.45% less ownership

Funds ownership: 101.83%100.38% (-1.5%)

3% less funds holding

Funds holding: 288280 (-8)

14% less first-time investments, than exits

New positions opened: 30 | Existing positions closed: 35

20% less call options, than puts

Call options by funds: $9.29M | Put options by funds: $11.7M

25% less funds holding in top 10

Funds holding in top 10: 86 (-2)

Holders
280
Holders Change
-8
Holders Change %
-2.78%
% of All Funds
4.31%
Holding in Top 10
6
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-25%
% of All Funds
0.09%
New
30
Increased
98
Reduced
108
Closed
35
Calls
$9.29M
Puts
$11.7M
Net Calls
-$2.37M
Net Calls Change
-$20.2M
Name Holding Trade Value Shares
Change
Change in
Stake
Stifel Financial
126
Stifel Financial
Missouri
$2.15M -$57.6K -551 -3%
IBT
127
International Biotechnology Trust
United Kingdom
$2.09M
WG
128
Winton Group
United Kingdom
$2.03M -$1.15M -10,951 -37%
Royal Bank of Canada
129
Royal Bank of Canada
Ontario, Canada
$1.91M +$920K +8,792 +97%
Principal Financial Group
130
Principal Financial Group
Iowa
$1.79M -$715K -6,836 -29%
MAM
131
Martingale Asset Management
Massachusetts
$1.74M -$1.16M -11,053 -41%
SFI
132
Susquehanna Fundamental Investments
Pennsylvania
$1.71M +$1.67M +15,950 New
CAPTRUST Financial Advisors
133
CAPTRUST Financial Advisors
North Carolina
$1.69M +$101K +964 +6%
Los Angeles Capital Management
134
Los Angeles Capital Management
California
$1.69M -$18.2K -174 -1%
Walleye Capital
135
Walleye Capital
New York
$1.66M +$1.62M +15,461 New
ASRS
136
Arizona State Retirement System
Arizona
$1.6M -$12.6K -120 -0.8%
MLICM
137
Metropolitan Life Insurance Company (MetLife)
New York
$1.6M -$45.4K -434 -3%
ADIM
138
Alpha DNA Investment Management
Maryland
$1.55M +$1.51M +14,459 New
HCA
139
Harbor Capital Advisors
Illinois
$1.53M +$1.5M +14,314 New
Envestnet Asset Management
140
Envestnet Asset Management
Illinois
$1.5M -$335K -3,200 -19%
HS
141
HighVista Strategies
Massachusetts
$1.48M +$118K +1,127 +9%
Squarepoint
142
Squarepoint
New York
$1.43M +$1.4M +13,387 New
AP
143
AtonRa Partners
Switzerland
$1.4M +$91.3K +873 +7%
BNP Paribas Financial Markets
144
BNP Paribas Financial Markets
France
$1.32M +$193K +1,846 +18%
DIA
145
Dana Investment Advisors
Wisconsin
$1.32M -$730K -6,976 -36%
TRSOTSOK
146
Teachers Retirement System of the State of Kentucky
Kentucky
$1.29M
TIP
147
Torray Investment Partners
Maryland
$1.24M -$457K -4,368 -27%
BC
148
Brookfield Corp
Ontario, Canada
$1.22M +$1.19M +11,414 New
Janus Henderson Group
149
Janus Henderson Group
United Kingdom
$1.2M +$590K +5,637 +101%
Teacher Retirement System of Texas
150
Teacher Retirement System of Texas
Texas
$1.13M +$176K +1,687 +19%

BPMC Hedge Fund Activity: Q4 2021 in Review

280 of the 6,498 institutional investors tracked by Wall St. Rank reported a position in Blueprint Medicines (BPMC) for Q4 2021, worth a combined $6.29B — up 2.8% from $6.12B a quarter earlier.

Sellers outnumbered buyers: 35 funds closed out of BPMC and 30 opened new positions — a net loss of 5 holders — while 108 trimmed existing stakes and 98 added.

The largest buyer was Marshall Wace, adding an estimated $96.6M. The largest seller was Fidelity Investments, cutting an estimated $90.3M.

  • 280 institutional investors held Blueprint Medicines (BPMC) as of Q4 2021, down from 288 in Q3 2021.
  • Funds reported $6.29B of Blueprint Medicines stock for Q4 2021, up 2.8% quarter-over-quarter.
  • 30 funds opened new Blueprint Medicines positions in Q4 2021 and 35 closed out, a net change of -5 holders.
  • The largest Blueprint Medicines buyer in Q4 2021 was Marshall Wace, an estimated $96.6M added.
  • The largest Blueprint Medicines seller in Q4 2021 was Fidelity Investments, an estimated $90.3M sold.

Based on aggregated 13F filings for Q4 2021.